One of the issues to overcome is the advantage machines can have in individual unit manipulations vs what a human can do in terms of APM https://www.youtube.com/watch?v=SZawUuAccnc
The problem is, as ActionButton argues in this review of Diablo 2 [0], Starcraft is a game that may contain some amount of strategy, but wherein the element of strategy is strongly over-powered by a reflex-based combat system more akin to Street Fighter than anything else. [0] http://www.actionbutton.net/?p=518
This isn't true, in general a bigger army will beat a smaller army every time.
After you can make equal size armies, the next problem is army positioning and when to take engagements.
Finally, after you can do all that, then you can get an extra bonus to your power by microing really well. But not every micro is about speed - most of the time it's about knowing what to do.
And even at the most extreme, it's less about clicking quickly and more about clicking precisely.