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Caffeine use disorder

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Re: Caffeine use disorder

#71

The thing to remember with caffeine is its half-life in non-smokers is 8 hours (it is 3 hours in smokers). I have a rule to never have any drink with caffeine after midday - if I break this rule even by an hour I suffer that night and the next day. Caffine is a morning drug.

There's also a gene that determines if you're a fast or slow metabolizer, I think it affects half life by around a factor of two. 23AndMe checks the associated SNP.

Re: Caffeine use disorder

#72
post #59
post #33

Earlier quoted context omitted.

I tried a couple times to get off caffeine, never worked properly... I don't feel obvious caffeine effects, but I need it to not be a wreck. Later I discovered I was self-medicating my ADHD... Now I am taking proper ADHD meds, and this allowed me to greatly reduce my caffeine use (that was wandering into dangerous and expensive territory, with me needing to drink litres of red-bull clones to work), still need it some…

Do you still live in Brazil? I've read criticisms here on HN, of doctors too eager to diagnose ADHD (specially in children) - did you felt that your doctor was aware of those issues? I ask because I'm not sure if I have ADHD or just regular anxiety/lack of focus that could be fixed by exercising/meditation/finding another job. And I don't want to go to the doctor to get hooked on drugs I don't need...

I am still in Brazil...

And I've been hearing about the ADHD overdiagnosis problem for a while, and I've been staunch that I didn't had ADHD until my life was the shithole that it is now (I am 28, unemployed, don't own any property, have negative net worth, no friends, no romantic partners...)

Then what I found was the opposite, as an adult, seeking for ADHD diagnosis (or diagnosis of whatever I had), led to most doctors spin around in circles trying to find everything that I could have that is NOT ADHD, because they assumed I was just some kind of junkie or someone wanting to cheat tests in university, because here in Brazil all ADHD meds are of highly controlled nature (ie: they are classed the same as Morphine for example).

Eventually I found my current medic... that still is going VEEEERY slow in the dosage, the highest dosage she ever gave me was 1/5 of the maximum, and about 1/3 of what people get on average.

Still, even this low dosage helped, before I had the meds, I reached a point where I was spending more on caffeine than food every day (and this is in a country that exports coffee and erva mate, thus caffeine in general here is really cheap)

Re: Caffeine use disorder

#73

Earlier quoted context omitted.

This is highly personal, and there's no substitute for experiment. My rule is no (caffeinated) soda within an hour of bedtime, and no coffee within 3-4 hours, so the variation is wide. I don't smoke, by the way. As an aside, the whole "8 hour half-life" is astonishingly high, to me. Caffeine is nice, but it doesn't seem to have that strong an effect on me, and certainly nothing I notice 5-8 hours after. I drink quite…

As you say, the variation is wide. I can drink tea up until about 6pm without any problems, but if I have even one coffee after lunchtime I'm going to be up half the night regretting it.

It's the opposite with me. I can have coffee in the late afternoon, in some cases even in the evening, without problems--but if I have a tea after 3 pm or so, I'm sure to have trouble.

Might have something to do with the strength of the tea, though.

Re: Caffeine use disorder

#74
post #39

I discovered that if I only consumed caffeine when I had a Migraine headache, that it was the most effective medicine I could take provided I didn't already have a tolerance built up so I gave up caffeine in my 20s. Frankly, it was a lot harder than I thought it would be. I was plagued with minor but persistent headaches for almost a month and was exhausted most of that time since I was used to grabbing a cup of coff…

I've been fooling around with caffeine medicinally as a decongestant when I have a cold. Psuedoephedrine being strangely hard to acquire in these meth days. I've had excellent results. I believe my tolerance from tea drinking lets my brain sleep but the stimulant effects none the less let my sinuses clear.

Aside from jittery feelings, I am actually physically jittery if I drink too much caffeine so some hobbies involving couple square mm surface mount components have to be scheduled with tea or energy drink consumption. Two cups of nice black tea and I'm not hand soldering 0402 components that day, although its easy when I'm "sober".

Re: Caffeine use disorder

#75
post #66
post #37

I've given up caffeine for Lent[1]. It's been hard. Beforehand, I knew I had a bad coffee habit. In a typical day I'd drink, maybe 6 or 7 mugs of strong coffee. I'd tried to cut down many times, but never succeeded; there just seemed to be too many reasons in my life to have another coffee. So when Ash Wednesday (the start of Lent) came, I thought, "Now's the time to quit." The first day was fine. I didn't notice any…

> I've given up caffeine for Lent I've heard from many people on HN and elsewhere individually choosing something to give up for Lent. In my understanding, the traditional Lenten restrictions in most Christian churches that observe Lent are pre-specified dietary restrictions that are the same for everybody (for example, it was unexpectedly convenient for me as a vegan to visit Eastern Europe because the Eastern Ortho…

I can only really speak from the Roman Catholic perspective, but traditionally there are three pillars of Lent: fasting, prayer, and almsgiving. The requirements for fasting have varied over the centuries. The strictest fast is the Black Fast [1], which was regularly observed (I think) sometime around the Early or High Middle Ages. It's similar to the fast observed by the Orthodox, though it intensifies during Holy Week (only bread, salt, herbs, and water allowed). Up until the early twentieth century or so, Catholics were required to fast every day of Lent except Sundays [2] (i.e., take only one full meal a day with two small meals that cannot, combined, form a full meal).

In the modern Roman Catholic Church the fasting requirements have been substantially relaxed. The only requirements are fasting on Ash Wednesday and Good Friday and abstaining from meat on Fridays. The other days of Lent are still penitential days, but the bishops of the region have the authority to determine the form of the penance. In the United States the bishops have stated that it is acceptable to substitute fasting for some other form of penance determined by the individual.

My impression is that the Eastern Orthodox and Eastern Catholic churches still observe a much more rigorous fast, more like the Roman Catholic Church used to a few centuries ago. As a side note, I've always been the most impressed with the Coptic Christians. They observe, by far, the most rigorous fasting schedule. They fast 210 days out of the year! [3]

[1]: http://www.newadvent.org/cathen/02590c.htm

[2]: Hence Lent is strictly speaking only 40 days (a more biblically significant number) because the Sundays are excluded from the fasting.

[3]: https://en.wikipedia.org/wiki/Fasting_and_abstinence_of_the_...

Re: Caffeine use disorder

#76

Earlier quoted context omitted.

If you want to drink coffee, drink coffee. Using a goofball medieval study (with a sample size of literally 2 people) to justify your personal choice is pretty silly.

Your problem with sample size in this particular case is that you fail to account for its duration. Convert sample size to temporal units and you might draw different conclusions since p-values might not look as bad now. An average FDA trial is 3 years, so assuming the prisoners lived for 40 years on their prescribed caffeine diet, you get sample size of 2*40/3 = 26.7. Not bad for 17th century. Last but not least, tu…

This fallacy is known as "pseudoreplication": the erroneous belief that multiple samples (or a long measurement) of dependent data (i.e. the same person year after year) is equivalent to getting many independent samples.

If you measure the same two people year after year, you just measure their genetic predispositions and personal habits more and more precisely. You cannot distinguish them from the results of your coffee/tea intervention.

http://www.statisticsdonewrong.com/pseudoreplication.html

Re: Caffeine use disorder

#77
post #66
post #37

I've given up caffeine for Lent[1]. It's been hard. Beforehand, I knew I had a bad coffee habit. In a typical day I'd drink, maybe 6 or 7 mugs of strong coffee. I'd tried to cut down many times, but never succeeded; there just seemed to be too many reasons in my life to have another coffee. So when Ash Wednesday (the start of Lent) came, I thought, "Now's the time to quit." The first day was fine. I didn't notice any…

> I've given up caffeine for Lent I've heard from many people on HN and elsewhere individually choosing something to give up for Lent. In my understanding, the traditional Lenten restrictions in most Christian churches that observe Lent are pre-specified dietary restrictions that are the same for everybody (for example, it was unexpectedly convenient for me as a vegan to visit Eastern Europe because the Eastern Ortho…

I can only speak for Roman Catholicism. The only required Lenten restrictions are abstaining from meat on Fridays and fasting on Ash Wednesday and Good Friday. These restrictions are for everyone (apart from age and health exceptions).

Traditionally, Catholics choose to do additional self-discipline during Lent. The big three things that the Catholic Church encourages are increases in prayer, fasting, and almsgiving. The fasting part is where people often give up some type of food or drink, like coffee.

So the practice of giving up a personally-selected thing is not required, but it is encouraged and traditionally done as a way to come closer to God and prepare for Easter.

Re: Caffeine use disorder

#78
post #39

I discovered that if I only consumed caffeine when I had a Migraine headache, that it was the most effective medicine I could take provided I didn't already have a tolerance built up so I gave up caffeine in my 20s. Frankly, it was a lot harder than I thought it would be. I was plagued with minor but persistent headaches for almost a month and was exhausted most of that time since I was used to grabbing a cup of coff…

What was the medicine that ended up helping your migraines? I suffer from migraines semi-regularly and have at separate times taken Maxalt, Imitrex, or generic OTC migraine meds + caffeine.

No the op, but for me 50mg nortriptyline daily is the no-migraine magic. Been thru most of the other available meds and nothing worked, except zomig, which you take after onset and for me, relived the pain, but none of the other symptoms. Nortriptyline is a really old tricyic antidepressant/nerve pain med, with pretty low risk of interaction/bad reaction. Without it I have clusters of 2-6 migraines over 4-5 days every 3-6 weeks. If you don't get them regularly, you may not want to have to take something every day, but if you get them with any frequency, it's a million times worth it. I can miss up to 2 sequential doses without problem but if I miss 3 or 4 I will get a migraine every time.

Best of luck.

Re: Caffeine use disorder

#79

Earlier quoted context omitted.

What was the medicine that ended up helping your migraines? I suffer from migraines semi-regularly and have at separate times taken Maxalt, Imitrex, or generic OTC migraine meds + caffeine.

I think he meant caffeine + no caffeine tolerance.

"until about a year ago when I finally found a medicine that has successfully prevented Migraine (completely)"

Re: Caffeine use disorder

#80
post #37

I've given up caffeine for Lent[1]. It's been hard. Beforehand, I knew I had a bad coffee habit. In a typical day I'd drink, maybe 6 or 7 mugs of strong coffee. I'd tried to cut down many times, but never succeeded; there just seemed to be too many reasons in my life to have another coffee. So when Ash Wednesday (the start of Lent) came, I thought, "Now's the time to quit." The first day was fine. I didn't notice any…

I gave up caffeine for 2 years. Got tired of drinking just water, beer or milk. Sodas and coffee w/milk sugar are too tasty.

All I did to quit was pop advil for a few days. Quitting caffeine wasn't remotely difficult physically. I used to drink 3-4 liters of soda a day, so not some small amount. I quit because I was worried about diabetes even though I was a healthy weight (as per my doctor's instructions).

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