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If it a user-driven project, I almost always do a UI layout (which looks amateurish because i suck at UI), then make a database scheme, then write 'glue' to go between the UI and the database, handling any random bits of gathering, massaging, and manipulation of data along the way.

If it's a machine driven project (eg a micro controller talking to another device or whatever) I usually will hardcore/hardwire almost everything and then slowly add support for inputs, interrupts, etc.