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Alzheimer's disease mortality among taxi and ambulance drivers (2024)

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Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#91
post #3

Would love to see a study looking at people who spend significant time in video games that require spatial navigation. That could even be a form of therapy after diagnosis (which seems to become easier with biomarkers).

Look at https://seaheroquest.com/papers this is a game I designed and developed that links spatial performance to population scale navigation changes across 4.3m people.

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#92
post #2

The rate of fatality for Alzheimer’s among ambulance and taxi drivers is 3x lower than the general population. This is not observed in other transportation-related careers. The connection is believed to be the spatial reasoning involved in routing. No causative link is suggested.

Will we see a drop in alzheimers when the open world gaming population reaches that age? I mean, I can not just navigate my city, but multiple worlds!

There's a paper on it:

"Video gaming, but not reliance on GPS, is associated with spatial navigation" paper shows there was a significant association between self-reported weekly hours of video gaming and wayfinding performance.

https://www.sciencedirect.com/science/article/pii/S027249442...

Tested with Sea Hero Quest

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#94
post #2

The rate of fatality for Alzheimer’s among ambulance and taxi drivers is 3x lower than the general population. This is not observed in other transportation-related careers. The connection is believed to be the spatial reasoning involved in routing. No causative link is suggested.

What are some possibilities? 1. Those with spatial reasoning are less likely to develop Alzheimers 2. Ambo and Taxi drivers are less likely (for some reason) to develop Alzheimers AND their work leads them to develop good spatial reasoning. Any others? One consideration is that those with jobs requiring long periods of concentration drink less. Among other things.

It's about hippocampal size, so people with a larger hippocampus are less likely to get alzheimers as it's a barrier, lots of studies scanning London cabbies brains and they have enlarged hippocampus - it's believed to give a barrier against alzheimers.

So spatial navigational ability is another risk factor/biomarker (along with blood pressure, smoking etc)

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#95
post #2

The rate of fatality for Alzheimer’s among ambulance and taxi drivers is 3x lower than the general population. This is not observed in other transportation-related careers. The connection is believed to be the spatial reasoning involved in routing. No causative link is suggested.

Will we see a drop in alzheimers when the open world gaming population reaches that age? I mean, I can not just navigate my city, but multiple worlds!

With the open world™ minimap and objective markers on the corner of the screen? I suspect not :)

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#96
post #2

The rate of fatality for Alzheimer’s among ambulance and taxi drivers is 3x lower than the general population. This is not observed in other transportation-related careers. The connection is believed to be the spatial reasoning involved in routing. No causative link is suggested.

> The connection is believed to be the spatial reasoning involved in routing. This is triggering me lol. I was a Paramedic for 10 years and 3 of those years were before GPS existed and we had these awful 900 page 5" thick things we had to wield on the fly called Map Books. It was part of our probation period testing and they would time us to pick out the routes reliably within a certain deadline or not graduate from…

Amazing. Paper-based GPS before actual GPS was a thing.

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#97
If we've got data for 400 occupations, and studying the two obvious outliers (as shown in Fig 1), isn't this p-hacking? Not saying malice is involved, but with so many occupations, the statistical aberration would be not to find outliers that spuriously pass statistical significance testing.

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#98
post #2

The rate of fatality for Alzheimer’s among ambulance and taxi drivers is 3x lower than the general population. This is not observed in other transportation-related careers. The connection is believed to be the spatial reasoning involved in routing. No causative link is suggested.

Will we see a drop in alzheimers when the open world gaming population reaches that age? I mean, I can not just navigate my city, but multiple worlds!

I’m not sure because in many modern open world games you are just like a Uber driver following GPS from checkpoint to checkpoint. It would with old school games that relied on memorizing the world and had minimal or even no map indications.

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#100
post #29
post #24

Earlier quoted context omitted.

The taxi-driving Alz patients may overwhelmingly die of something that leads to physicians not listing Alz as a cause of death. If taxi driving is loaded in such a way that Alz presents significant challenges (eg loss of income), that could be the case.

But that's not a spatial reasoning connection. Also would include all other drivers.

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