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Alzheimer's disease mortality among taxi and ambulance drivers (2024)

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21–30 of 146 posts

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#21
post #2

The rate of fatality for Alzheimer’s among ambulance and taxi drivers is 3x lower than the general population. This is not observed in other transportation-related careers. The connection is believed to be the spatial reasoning involved in routing. No causative link is suggested.

Except causation, what can the connection be? Some genes causing both spatial reasoning and suppressing Alz?

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#23
post #5

I immediately go to these two thoughts: - Is significant life-long usage of real-time mental spatial navigation protective? - Are those who end up in these positions self-selected for better than average real-time mental spatial navigation and that above average performance correlates with protection against Alzheimer's.

I think your 2nd point is less likely. Anecdotal, but I've spoken with many taxi and ride-share drivers, and my impression is that their decision to seek out and continue that line of work is almost always driven by outside economic considerations. I've never heard someone base their decision on their ability to perform the job.

> I've never heard someone base their decision on their ability to perform the job.

That they’re consciously aware of

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#24
post #21
post #2

The rate of fatality for Alzheimer’s among ambulance and taxi drivers is 3x lower than the general population. This is not observed in other transportation-related careers. The connection is believed to be the spatial reasoning involved in routing. No causative link is suggested.

Except causation, what can the connection be? Some genes causing both spatial reasoning and suppressing Alz?

The taxi-driving Alz patients may overwhelmingly die of something that leads to physicians not listing Alz as a cause of death. If taxi driving is loaded in such a way that Alz presents significant challenges (eg loss of income), that could be the case.

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#25

I was really expecting this to be higher not lower due to factors like particulate inhalation from exhaust/brake dust/tire particles. Also there's a lot of sedentary-type problems you get while taxi driving like bad diet habits that are not conducive to brain health. Dunno, did taxi driving for a few years. Mostly suburban for a small fleet, not gigging. I'm thinking newer drivers that rely on smartphones for navigat…

I was thinking the same thing, about the tire particles and sedentary problems. It's really true the what you do for your daily work over many years shapes your body.

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#26
post #2

The rate of fatality for Alzheimer’s among ambulance and taxi drivers is 3x lower than the general population. This is not observed in other transportation-related careers. The connection is believed to be the spatial reasoning involved in routing. No causative link is suggested.

What are some possibilities?

    1. Those with spatial reasoning are less likely to develop Alzheimers
    2. Ambo and Taxi drivers are less likely (for some reason) to develop Alzheimers AND their work leads them to develop good spatial reasoning.
Any others? One consideration is that those with jobs requiring long periods of concentration drink less. Among other things.

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#29
post #24
post #21

Earlier quoted context omitted.

Except causation, what can the connection be? Some genes causing both spatial reasoning and suppressing Alz?

The taxi-driving Alz patients may overwhelmingly die of something that leads to physicians not listing Alz as a cause of death. If taxi driving is loaded in such a way that Alz presents significant challenges (eg loss of income), that could be the case.

But that's not a spatial reasoning connection. Also would include all other drivers.

Re: Alzheimer's disease mortality among taxi and ambulance drivers (2024)

#30
My first reaction to the title was: "duh, selection/survivorship bias" but their counter is pretty solid:

> Firstly and perhaps most importantly, selection bias is possible because individuals who are at higher risk of developing Alzheimer’s disease may be less likely to enter or remain in memory intensive driving occupations such as taxi and ambulance driving. This could mean that the lower Alzheimer’s disease mortality observed in these occupations is not due to the protective effect of the job itself but rather because those prone to the disease may have self-selected out of such roles. However, Alzheimer’s disease symptoms typically develop after patients’ working years, with only 5-10% of cases occurring in people younger than 65 years (early onset).1114 While subtle symptoms could develop earlier, they would still most likely be after a person had worked long enough to deem the occupation to be a so-called usual occupation, suggesting against substantial attrition from navigational jobs due to development of Alzheimer’s disease. Moreover, even if lifelong taxi driving selects for individuals with strong spatial processing, our findings would still suggest an interesting link between spatial processing skills and risk of Alzheimer’s disease.

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