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Schizophrenia: The new etiological synthesis

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91–100 of 128 posts

Re: Schizophrenia: The new etiological synthesis

#93
I will have to sit down and read this over the weekend.

But I'm a bit put off by its focus on evolutionary origins. It's prevalence is circa 1% (claimed in article at 0.76%), that's too rare to really gun for an evolutionary basis like you do for cystic fibrosis or sickle cell.

Circa 1/30 carries the CF gene which shows Mendelian inheritance and so we week a evolutionary basis.

Re: Schizophrenia: The new etiological synthesis

#94

Earlier quoted context omitted.

What you are describing sounds like a protracted psychotic break. Schizophrenia doesn’t just come one day and disappear 6 months later.

Maybe you are right. I watched a Netflix doc on schizophrenia a few days ago, and it was ‘check, check, check’ for nearly every symptom. I suppose there’s a lot of overlap with the more extreme mental health issues.

[deleted]

Re: Schizophrenia: The new etiological synthesis

#95
post #49

Earlier quoted context omitted.

Not usually, but schizophrenia is a waxing and waning disease like MS - patients tend to get episodes of worsening symptoms then remission (partial) where symptoms get better. Then they’ll get another relapse and often it’s worse, eventually resulting in a state of chronic symptoms. Treatment with antipsychotic medication can actually “pause” the cycles and prevent the disease from getting worse if started early. It’…

Schizophrenia is a degenerative condition where positive symptoms start to be replaced by negative symptoms over the course of years. I've worked in acute adult mental health, and did a few shifts in the long term wards and the difference between people earlier on in the course of their illness versus the end stages are stark.

I'm not fully convinced here, I bet those long term patients were on antipsychotics nearly all of which have extrapyramidal side effects, pretty identical to negative symptoms.

Re: Schizophrenia: The new etiological synthesis

#96

Earlier quoted context omitted.

What you are describing sounds like a protracted psychotic break. Schizophrenia doesn’t just come one day and disappear 6 months later.

Maybe you are right. I watched a Netflix doc on schizophrenia a few days ago, and it was ‘check, check, check’ for nearly every symptom. I suppose there’s a lot of overlap with the more extreme mental health issues.

Having a quick look through this thread just about nothing your describe fits well with traditional psychiatric disorders.

For example panic attacks almost by definition do not last more than 15minutes.

Although self diagnosis is near impossible, I mean how can you expect to be an objective observer of your self when you can barely watch TV? It's possible a trained psychiatrist would be able to make a snap diagnosis for you if they were able to watch and listen to you at the time.

Re: Schizophrenia: The new etiological synthesis

#97

Earlier quoted context omitted.

Maybe you are right. I watched a Netflix doc on schizophrenia a few days ago, and it was ‘check, check, check’ for nearly every symptom. I suppose there’s a lot of overlap with the more extreme mental health issues.

Having a quick look through this thread just about nothing your describe fits well with traditional psychiatric disorders. For example panic attacks almost by definition do not last more than 15minutes. Although self diagnosis is near impossible, I mean how can you expect to be an objective observer of your self when you can barely watch TV? It's possible a trained psychiatrist would be able to make a snap diagnosis…

That was just my very first, introductory panic attack.

I did have another which lasted a very very long time when I was outside, but I was given a shot of adrenaline for that one.

The thousands of others have been under 15mins.

Re: Schizophrenia: The new etiological synthesis

#98

Earlier quoted context omitted.

Schizophrenia is a degenerative condition where positive symptoms start to be replaced by negative symptoms over the course of years. I've worked in acute adult mental health, and did a few shifts in the long term wards and the difference between people earlier on in the course of their illness versus the end stages are stark.

I'm not fully convinced here, I bet those long term patients were on antipsychotics nearly all of which have extrapyramidal side effects, pretty identical to negative symptoms.

It’s worth mentioning here that antipsychotics have come a long way since lithium. (Posting from the US with our unfortunate (relative to the developed world) healthcare system.)

There’s a handful of antipsychotics and mood stabilizers that have been developed in the last couple of decades that have had unprecedented success with Schizophrenia and Bipolar Disorder. They typically cost $20,000.00 per year before insurance (mine is $0.00 per year after insurance and a coupon, and they get cheap when their patent expires (the patent-clock is 20 years and starts when development starts)). I get to lead a normal life thanks to my medication, and I have experienced no side effects besides the typical mild brainwashing (totally worth it when compared to the alternative). I have friends on other similar newfangled medication, and they have similarly wonderful results.

Please forgive the Lisp-ish parentheses. I figure it’s halfway acceptable on HN.

Re: Schizophrenia: The new etiological synthesis

#99

Earlier quoted context omitted.

Having a quick look through this thread just about nothing your describe fits well with traditional psychiatric disorders. For example panic attacks almost by definition do not last more than 15minutes. Although self diagnosis is near impossible, I mean how can you expect to be an objective observer of your self when you can barely watch TV? It's possible a trained psychiatrist would be able to make a snap diagnosis…

That was just my very first, introductory panic attack. I did have another which lasted a very very long time when I was outside, but I was given a shot of adrenaline for that one. The thousands of others have been under 15mins.

You were given a shot of adrenaline for a panic attack?

Re: Schizophrenia: The new etiological synthesis

#100
post #83

Earlier quoted context omitted.

I would so love to chat with someone with your experience. I developed tourettes / ticking a few years ago when I was around 32 and I wonder whether it could be related to the psychosis I once had. When I researched sudden onset ticking I couldn’t really find much about it! There hasn’t been a day in past 4 years I’ve not ticked and it is worse than ever.

Curious if you've heard about socially-induced Tourette-like behaviours? There was a HN post about it not too long ago, one of the signs was sudden onset later in life: https://news.ycombinator.com/item?id=33878155

Funny you mention this, because it was only when that story came out that I could even find info about sudden onset Tourette's in people. Mines is the full vocal and movement ticks. But ticks only happen when I get memory flashbacks, which are approximately 50-100 times a day.
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