Earlier quoted context omitted.
My wife is 32 and all her friends and relatives have guessed my age at 36.
Good for you! But hasn't this always been the case i.e. looking / 25 when you were 36?
I'm 52, not 36 however.
Scientists identify pathways that extend nematode worm lifespan fivefold
91–100 of 112 posts
Re: Scientists identify pathways that extend nematode worm lifespan fivefold
#92Earlier quoted context omitted.
You can substitute it with over-the-counter Berberine: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839379/
Or take both like I do. Berberine is not as effective as metformin, but every bit helps when lowering blood sugar levels go.
Where do you get metformin from?
Re: Scientists identify pathways that extend nematode worm lifespan fivefold
#93Earlier quoted context omitted.
Does your father looks a lot younger too? My father is in his mid 50s and he looks 40. I am in my mid 30s and I look younger too. This is genetics obviously. I am also doing fasting 16/8 and eat less than most people. It's possible that those supplements have 0 effects and it's all just genetics.
Not really but he smoked for 40 years before quitting around age 55. Or it’s possible the preliminary results are correct.
> Not really but he smoked for 40 years before quitting around age 55.
My father smoked for around 30 years, I've smoked for around 16 years.
> Or it’s possible the preliminary results are correct.
Sure, it's a possibility too, I would like to see more long term studies tough, with enough participants to statistically exclude all environmental noise.
For now we can be sure of one thing, genetics is the main factor in how we age.
Re: Scientists identify pathways that extend nematode worm lifespan fivefold
#94Earlier quoted context omitted.
I'm sorry that you're suffering. No one should discount your experience. Yet even through our cloudy lens we behold a miracle beyond our possession, even beyond our comprehension. We are all transitional forms, even the best of us. We'll all die. It's nature's equalizer, grinding everything to dust and recycling it. We're all made of garbage. Junkyard parts, you and me both, buddy. Isn't it incredible? We're all Wrec…
Miracles do not necessarily have to be positive. Imagine Dante's inferno, where in some sections fire might rain down forever upon the limited sinners. That would also be a miracle. Possession, comprehension of miracles, all irrelevant if it is something to which you are subjected . If you are ill, if you are very ill and occasionally must ingest large quantities of painkillers, marveling at the exquisite engine of t…
I'm not going to negate you here, because you have a lifetime of lived experience and I don't doubt your pain is and has been real. Yet people suffer in many ways and there are some deeply twisted realities that many people have lived. In our darkest moments we all feel we are the tortured one, but that is not the whole truth either. It is tempting to believe that we are at war with an implacable, all-powerful enemy. But truthfully, we are only at war with our own minds.
The mind is ultimately a digging machine. It matters a lot where you point it, more even the lens through which you interpret all that you see. Some very disadvantaged people have put forth some incredible feats of overcoming. They refused to be defined by their disabilities, their pain, their hardship--and refused to rue their existence. This engine grinds us all, but this world is no hell. And that damn octopus, maybe he reaches the height of ecstasy in that moment, an orgasm beyond belief. Wicked is a judgment.
Re: Scientists identify pathways that extend nematode worm lifespan fivefold
#95Earlier quoted context omitted.
Evolution is not always correct. Evolution is correct only for a certain set of circumstances at a certain point in time. Appendixes are an example of legacy evolutionary artifacts. Evolution keeps...evolving. So one could argue that mortality is a legacy evolutionary process and by overcoming it humans are evolving as a species. Think of all one could accomplish if dedicated 1000 years of learning and research to de…
I'm not sure our brains are capable of continuously learning for 1000 years without becoming useless. Also, there is a dystopian version of immortality - a tiny fraction of elites becoming immortal super-tyrants.
If we solve aging we may solve brain aging as well as one is a subset of the other.
Re: Scientists identify pathways that extend nematode worm lifespan fivefold
#96Earlier quoted context omitted.
By the same token, there are animals who have the „live for 400 years“ problem solved so there must be sth left on the table yes? Other animals have the „regenerate this body part“ problem solved, same.
"By the same token, there are animals who have the „live for 400 years“ problem solved so there must be sth left on the table yes?" Note my claim wasn't that optimization isn't possible, just that the impressiveness of the optimization is inversely proportional to the amount of performance left on the table. In terms of that being a promising avenue, I'd observe all the animals with long lifespans I'm aware of seem t…
I don't want my old brain - just the information stored inside.
Re: Scientists identify pathways that extend nematode worm lifespan fivefold
#97Earlier quoted context omitted.
"By the same token, there are animals who have the „live for 400 years“ problem solved so there must be sth left on the table yes?" Note my claim wasn't that optimization isn't possible, just that the impressiveness of the optimization is inversely proportional to the amount of performance left on the table. In terms of that being a promising avenue, I'd observe all the animals with long lifespans I'm aware of seem t…
I don't want my old brain - just the information stored inside.
Then would it still be you?
Re: Scientists identify pathways that extend nematode worm lifespan fivefold
#98Whats interesting is that according to the Bible humans lived from several hundred years to ~1000 years. Now this article is saying "The increase in lifespan would be the equivalent of a human living for 400 or 500 years, according to one of the scientists." Mind blown! Ages of the Patriarchs from Adam to Noah: 1. Adam 930years Genesis 5:4; 2. Seth 912years Genesis 5:8; 3. Enosh 905years Genesis 5:11; 4. Cainan 910ye…
we're trying to have an intelligent discussion here and you bring religious garbage
why was my comment not intelligent? if anything - peoples reaction so far to a simple comment is not tolerant and pure garbage. i simply quoted bible (im not religious) and folks here lost their marbles. says something about these people if you ask me!
Re: Scientists identify pathways that extend nematode worm lifespan fivefold
#99Earlier quoted context omitted.
1 gram of NMN, metformin and resveratrol. Beyond that I take other things including carbon 60. Those are the most exotic items; the rest are your usual items such as fish-oil, krill oil, multi-vitiman most of which I tuned from my Inside-Tracker.com blood results. I also have the right genetics; aka longevity gene(s), Ashkenazi Jew markers, etc and my farther is in his upper 80's; his mother lived to 98. I don't want…
I do all of those things, but I am finding the NMN to be quite costly. I take almost the same amount as Dr. Sinclair, which means going through a bottle of pills every three to five days. I really hope someone makes a less expensive version soon. I do feel the difference and can probably attribute it to higher ATP production. I have no idea if it's helping my cardio vascular system.
How many milligrams of NMN do you take each day?
Re: Scientists identify pathways that extend nematode worm lifespan fivefold
#100Dang, my retirement savings will have to last much longer than I had expected.
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