91–100 of 172 posts
That doesn't sound like a "cure" to me. Significant progress to be sure, but in my mind to be considered a "cure" the mortality rate would have to drop to near zero.
I really have to apologize if this is not a HN-quality comment, but I initially read this as a startup rebrand announcement. Ebola is now Curable (YC 17)
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Turn off javascript for wired.com and it works well. I use uMatrix to do it. https://imgur.com/dg4MpiY
I use uBlock Origin to do it. It took me years to find it was the small button in the bottom right corner. Don't forget to save the settings for this website afterwards.
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> I want to know how long it will take for Ebola to evolve a resistance to this therapy. Maybe never. A lot of time in any case, probably. Ebola is a plant's virus adapted to trees. Evolved to use bats (and probably arboreal snakes also) but can't survive for a long time in primates, and can't survive in soil at long term. We are a dead end for it. Would need infected humans munching some inedible leaves of a tropica…
> Ebola is a plant's virus adapted to trees. I never heard that and I can't find that in Wikipedia. Do you have a link with more information about that?
Ebolavirus is a genus comprising at least five species that can create similar outbreaks. I don't know if the treatment protects from all of them (Probably not). Is a fast mutating kind of creatures also. I guess that each future outbreak will need to rebuild an specifical treatment. The good news is that we know how to rebuild it fast, there is a new awareness of the problem, and african people are fixing some cultural traditions that helped to spread the virus in the past.
There are also other two genuses closely relative to Ebolavirus: Marburgvirus (produces a similar haemorrhagic fever in humans), and the spanish surprise Lloviu cuevavirus (poorly known but assumed harmless). Treatment designed for Ebola probably will not protect from Marburg disease, but I'm speculating.
WHO: two of the four drugs we thought would work did not work as well as expected. WIRED: EBOLA CURED https://www.niaid.nih.gov/news-events/independent-monitoring...
Off topic, but does this meme/way of writing have a name? It's used a lot in Youtube comments and it weirdly grates me.
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It's only a "great way to create statistical fraud" if you assume that the statisticians, and the FDA, are either stupid or corrupt. And contrary to popular belief, they tend to be competent enough to at least cope with the sort of hair-brained schemes HN believes would fool them.[0] Stopping a trial early and it's statistical implications should, by the way, be somewhat familiar with web developers: it's commonly do…
>> the sort of hair-brained schemes HN believes would fool them Is there much value in an ad-hominem reply? Or in generalizing it to an entire community? The irony seems hard to avoid when such a generalization is made without mentioning any statistical foundation, while pontificating about statistics.
There is no news I enjoy reading more than that a clinical trial had to be ended early because the treatment was so effective that it would be unethical to continue with alternative treatments (or a placebo).
Actually, it's quite terrifying when you remember that stopping a clinical trial early is a great way to create statistical fraud. https://blogs.sciencemag.org/pipeline/archives/2019/08/08/st... cites an example of a drug whose clinical trial was stopped early due to obviously effective success... only to discover later on that the "obviously effective" was a statistically spurious event, and the drug did not confer…
Earlier quoted context omitted.
It's only a "great way to create statistical fraud" if you assume that the statisticians, and the FDA, are either stupid or corrupt. And contrary to popular belief, they tend to be competent enough to at least cope with the sort of hair-brained schemes HN believes would fool them.[0] Stopping a trial early and it's statistical implications should, by the way, be somewhat familiar with web developers: it's commonly do…
>> the sort of hair-brained schemes HN believes would fool them Is there much value in an ad-hominem reply? Or in generalizing it to an entire community? The irony seems hard to avoid when such a generalization is made without mentioning any statistical foundation, while pontificating about statistics.