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Trials on veterans suggest ibogaine could provide a new treatment for PTSD

bbc.com

81–90 of 136 posts

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#81

The article acts like ibogaine is a newly discovered drug. This is an old hallucinagenix drug that has helped thousands of people get over ptsd. The only thing holding this back is government bureaucracy and red tape. I’m happy that people will get there chance to benefit from this after decades of stupid government policy.

I have a friend who received ibogaine as a treatment, in mexico, for opiate addiction and it is not at all like your average hallucinogenic drug. for starters, she had to go through cardiac tests before they would even administer the stuff because it can cause serious cardiac symptoms, up to and including death. Somebody in her group was kicked out because they had been using meth the week of the trip (no pun intende…

But did it work?

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#82

Earlier quoted context omitted.

I have a friend who received ibogaine as a treatment, in mexico, for opiate addiction and it is not at all like your average hallucinogenic drug. for starters, she had to go through cardiac tests before they would even administer the stuff because it can cause serious cardiac symptoms, up to and including death. Somebody in her group was kicked out because they had been using meth the week of the trip (no pun intende…

But did it work?

as far as I know. She also had to do serious therapy and addiction recovery stuff, so it wasn't like she was magically cured of being addict simply by using ibogaine, in, case that is how my story came off.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#83
post #54

Earlier quoted context omitted.

What in the world are you talking about? There are 0 requirements for head trauma with PTSD, it's a stress response. Cognitive Behavioral Therapy is the top tier, evidence based treatment for PTSD. 60-80% can actually lose their PTSD diagnosis through CBT in some studies. I'm not saying CBT is the magic cure, but it's very helpful for retraining the body's fight or flight response. For TBI, there is not really any am…

WW1 shellshock was a diagnosis consisting of an undifferentiated mix of concussion and ptsd, the diseases may have been completely untangled by now but it’s not impossible that there is still some blurring

Maybe in 1918 we thought so but we've known better since prior to the DSM-III in 1980. Over 46 years.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#84

Earlier quoted context omitted.

Please provide a source for your claim that deaths have occurred in clinical trials under medical supervision .

https://pubmed.ncbi.nlm.nih.gov/35012793/ I’m sure someone will find some reason to dismiss or excuse these deaths, as anyone who brings up the negatives of psychedelics is usually shouted down on this site. The cardiotoxic effects of ibogaine are well known, though. This is why analogs without the cardiotoxic effect are an active area of study. Of all of the incredible claims about ibogaine in this thread it’s sad t…

To give context to this, the person didn't post a study in which anyone died, instead a study that claims 2 people have died in 2 separate studies. Despite this claim, it actually only references one of these studies, the second one is never referenced.

If you look at, at the one referenced study, there was a coronial inquiry and an investigation by New Zealand's Health and Disability Commissioner that found the doctor who was supervising was in breach of their duty of care.

Yes, there can and have been negative side effects for MANY drugs, but blaming the drug, when a government body has investigated the incident placed the blame elsewhere is an outrageous bad faith claim.

Additionally, that study was for Opioid addiction, and a person also died before even getting into the study (so, iBogain is probably the lesser of two evils).

As for the snarky comment about people finding excuses on this site, no, people actually just read citations on this site, instead of just trust me bro. When your citation claims a doctor is responsible, but you say it was the drug, do you see how one can only assume you are disingenuous?

The full Journal is here: https://www.tandfonline.com/doi/full/10.1080/00952990.2017.1...

Here is a relevant extract:

> A third patient of Provider 1 died during treatment before they were formally enrolled. Of 13 participants enrolled through Provider 2, one voluntarily left the study at eight months and a second was lost to follow up at 11 months post-treatment. The fatality was the subject of two investigations, a coronial inquiry and the second involving New Zealand’s Health and Disability Commissioner (HDC). The latter, completed first, described the treatment provider as being in breach of their duty of care but did not offer a medical explanation for the death.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#85
I’m sorry, but people really need to understand how these drugs “treat addiction“. ibogaine acts on an opioid receptor. So all you’re doing is changing one opiate for another.

It acts on the KOR receptors instead of the MOR receptor, which most openly act on. But it’s not like you’re going to be cured from opioid addiction. You’re just replacing one opioid with another that doesn’t affect the respiratory system.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#86
post #6

Earlier quoted context omitted.

Saliva divinorum is inherently dysphoric due to its agonism of the kappa opiod receptor. For a different cheap legal drug that affects serotonin and the NMDA receptors like ibogaine does, there's always off label use of dextromethorphan (cough medicine)!

Really difficult to find a cough syrup with only high amounts of DXM and nothing else. All the brands changed their recipes in the late 90s.

They just sell DXM in softgels and tablets now

Edit: apparently that’s not true. There’s a brand of DXM-only syrup called Robocough now. What a ridiculous name for a Legitimate Cough Medicine

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#87
post #13

I always wonder why ECT doesn't get more press. It very very often works on depression (and bipolar disorder, catatonia; anything affective-related really), although the effects may wane over time when the treatment is discontinued. Memory loss is one of the side effects, and it could actually be beneficial here.

I had a friend who just went through ECT. It did nothing for their depression and I left them with severe memory loss, and cognitive decline.

You’d be surprised to read the statistics about how poorly ECT works, and how little they understand about how to use it a treatment.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#88
post #13

I always wonder why ECT doesn't get more press. It very very often works on depression (and bipolar disorder, catatonia; anything affective-related really), although the effects may wane over time when the treatment is discontinued. Memory loss is one of the side effects, and it could actually be beneficial here.

It's strange how much attention novel psychedelic treatments get compared with older, less glamorous interventions that already help a lot of people

Yeah, super weird how people want to get away from the "less glamorous" intervention of deliberate brain damage.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#90
post #75
post #70

Earlier quoted context omitted.

What a strange and presumptive thing to say. I'm wondering why not all PTSD cases, why specifically this relatively small group? Like, obviously we should treat veterans with PTSD, but the article is unclear about whether it's just them.

> I'm wondering why not all PTSD cases, why specifically this relatively small group? Because then it’s another variable in the study.

That's a reasonable answer!
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