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Eating in 10-hour window can override disease-causing genetic defects

salk.edu

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Re: Eating in 10-hour window can override disease-causing genetic defects

#81

Is it possible that with economic affluence of the West, overconsumption is harmful? It used to be that there would be days where our ancestors would not be able to bring home any meat so fasting probably was built in as part of our metabolism process. It was only in the past 100 years that we've seen mass produced sugary food and drinks. Like the diet difference is painfully obvious when you go to Japan's 7-11. Heal…

I live in Vietnam but we have a lot of Koreans in the area I live in and what they eat doesn't seem very healthy. Huge amounts of cheese and grilled meats and very heavy drinking. Is that typical for Koreans in Korea too?

Yes, it's a very unhealthy combo to do frequently. The bovine industry along with a connected global marketplace has made it far more abundant than is healthy.

For example, I heard that samgyupsal is mostly fat that isn't typically consumed for grilling, is really unhealthy as it consists mostly of fat lard with little pork meat. but once you taste it it's hard to put down. Typically, lettuce, garlic, onion, sesame oil and in traditionally green onions shredded with red pepper sprinkled. You take a bit of meat, bathe it in the sesame oil sauce with pepper and salt, wrap it up in lettuce, throw in some fermented bean sauce containing healthy probiotics also found in kimchi, and pop it in your mouth. When you get a bit tired of the grease, you yell "WUN SHUT!" ("one shot") and down what seemingly smells like acetone. There's a euphoria that happens when you combine it with family and friends, it's also a common way to bond with your co-workers and superiors.

Typically a traditional Korean meal consists of rice and banchan, or seasoned side dishes, but most people I know just eat rice and kimchi. Also, Koreans have a huge affinity for Pho and vietnamese cuisine because it feels familiar.

Writing about samgyupsal has gotten me salivating lol....

    "My mind is telling me no, but my body....my body is telling me YES"

     - R. Kelly

Re: Eating in 10-hour window can override disease-causing genetic defects

#82
post #62

Earlier quoted context omitted.

Everything you said sounds like bullshit, do you have any source to back it up?

https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072577/ Through an evolution lense we evolved to not be eating huge meals in the middle of the night. When the liver doesn’t have to work on digestion it can better focus on the myriad of other tasks it’s responsible for. As for mayurasana, I doubt any pharma company is going to drop 500 Gs to perform a double blind random controlled study with >1000 participants , but ju…

Governments would pay for it. As would health insurances. It is in their own benefit that they study this sort of thing. "Big pharma companies" won't because that is honestly outside their field of study, which is the development of pharma products. It seriously isn't worth taking money away from better treatments for malaria or cancer to study it. However, universities and goverments and health insurance companies would be interested. The first is because some universities are research centers and the other two are interested in lowering their costs for health care. Simple solutions are good for these groups.

And about the woman stuff? I don't buy it. Of course they would drop money on it - at the same rate they drop money on menstral studies, anyway (it isn't as much as some other things, but they do study such things). Part of the menstral process is contributed by muscle cramps and gravity. Lying down in general will sometimes make things slow down, especially on the last day or two. Once the person is upright, the person might simply have a heavier flow those days. Without studies, this sort of advice is simply founded in superstition.

Re: Eating in 10-hour window can override disease-causing genetic defects

#83
post #59
post #40

Earlier quoted context omitted.

It sounds like you were just starving yourself. I'm going to guess that you weren't eating 2-5 days worth of food whenever you chose to eat? I'm sorry but going that long without eating just doesn't make any sense. Did you/your family only have the ability to buy/acquire one meal at a time or what?

> I'm sorry but going that long without eating just doesn't make any sense. That would be great news to the lower 1-2 billions in the developing world.

I was saying it doesn't make sense to be eating once every 2-5 days, but eating 2-5 days worth of calories during those meals. Obviously if you are food insecure you don't have a choice - but if you have access to the food, only touching it every couple days doesn't make sense.

Even if you have to survive on little money, I don't understand why you would go that long without food and not at least have some ultra cheap foods like rice and beans in your fridge.

Re: Eating in 10-hour window can override disease-causing genetic defects

#84
post #38

Is it possible that with economic affluence of the West, overconsumption is harmful? It used to be that there would be days where our ancestors would not be able to bring home any meat so fasting probably was built in as part of our metabolism process. It was only in the past 100 years that we've seen mass produced sugary food and drinks. Like the diet difference is painfully obvious when you go to Japan's 7-11. Heal…

> our ancestors have been eating the same stuff for millenias so it's probably "right" for my metabolism. There might be a genetic factor here. The other thing is that the food habits of our ancestors were more thought out than we think. It might be that what they have been eating is not only better because of genetics, but more healthy in general than the terrible foods we can buy everywhere today.

Absolutely. It's fascinating how different dietary cultures develop and adapt to their environment in a surprisingly efficient manner. Nothing is wasted. Need to store meat for long periods of winter? Smoke it. Need it on the go? We'll use the left over bits to make sausages. What? You need side dishes that doesn't go bad for a long time? We'll pickle it, store it under ground to ferment it. Huh, you are throwing away all that extra cabbage roots from making kimchi? Put that in a soup or 시락국 containing high levels of Omega-H3 from the broth containing tiny fishes.

Re: Eating in 10-hour window can override disease-causing genetic defects

#85

Interesting how this time restricted eating seems to differ from perspectives in the intermittent fasting community. Intermittent Fasting folks tend to espouse avoiding caloric intake for long periods of time every day, but they're fine with black coffee/tea (since it doesn't trigger an insulin response). But here Dr. Panda seems to believe that even coffee would compromise the fasting window: https://youtu.be/iywhaz…

I just signed up and installed their iOS app. You are correct: drinking coffee or tea in the morning starts the non-fasting period. This will be rough for me because I usually have coffee at 5:30am, read or study for 90 minutes, then have breakfast and go to work. I will shift my morning coffee to when I have breakfast. I have been non-fasting and fasting with an even split of 12 hours / 12 hours per day, so this wil…

> drinking coffee or tea in the morning starts the non-fasting period

major bummer. I almost entirely rely on caffeine while I'm fasting and it inhibits my appetite.

Re: Eating in 10-hour window can override disease-causing genetic defects

#86
post #75

Earlier quoted context omitted.

It's actually not as hard as you think for experimental design to show strong causitive effects - I think randomized controlled trials (in animal and then human models) and meta-analysis are much more effective than epidemiological studies (which don't have effective controls, often don't appropriately correct for other factors, or are specific enough to target specific lines of inquiry and allow spurious conclusions…

I've been doing this for more than 17 years. Some thoughts: 1. Anything that makes a real change will have side effects. Some of those side effects can be negative. For people not familiar with the concept of a healing crisis, this can be a confusing fact. They can end up temporarily feeling worse and conclude this is a bad thing rather than a temporary stage of a process headed in the right direction. 2. Prescribed…

I agree that it's really complex and not straightforward, especially since there are so many unknowns, confounding factors, and since so much is different from person to person (microbiota, genetic and especially epigenetic factors, the effects of hormesis, etc) but at the same time, just because it's complex doesn't mean that science (or individuals) should throw their hands up and say "well, there are no conclusions that can be made about human diet" as that seems to be patently untrue.

Also, just because people can't read hundreds of studies doesn't mean that they aren't out there, or that haven't been done (tens of thousands of studies, of all kinds, which taken together do point to much more specific things than "eat some nuts"), or that it's excusable when medical professionals make recommendations that are contradicted by the preponderence of scientific evidence.

Re: Eating in 10-hour window can override disease-causing genetic defects

#87
post #86

Earlier quoted context omitted.

I've been doing this for more than 17 years. Some thoughts: 1. Anything that makes a real change will have side effects. Some of those side effects can be negative. For people not familiar with the concept of a healing crisis, this can be a confusing fact. They can end up temporarily feeling worse and conclude this is a bad thing rather than a temporary stage of a process headed in the right direction. 2. Prescribed…

I agree that it's really complex and not straightforward, especially since there are so many unknowns, confounding factors, and since so much is different from person to person (microbiota, genetic and especially epigenetic factors, the effects of hormesis, etc) but at the same time, just because it's complex doesn't mean that science (or individuals) should throw their hands up and say "well, there are no conclusion…

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Re: Eating in 10-hour window can override disease-causing genetic defects

#88

Earlier quoted context omitted.

>Breaks a fast" is meaningless without specifying what we mean by that. If we mean "breaking fast = you eat something with calories" then yes, but then it's a tautology. Yes...that is how definitions work. Consuming calories triggers a metabolic response and breaks a fast. That is the generally accepted definition of breaking a fast. There are types of fasts dry fast, water fast, intermittent fast. But the fast part…

"The idea some religion somewhere ate plants only a called it a fast, doesn’t make it a fast." Yes, it absolutely does, and sometimes comes along with abstaining from food entirely for short times. Not only that, but there are usually exceptions for children, the sick, and the elderly. Medical fasting sometimes means "nothing" and sometimes means "clear liquids" or a combination. It all depends on context. I was rais…

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Re: Eating in 10-hour window can override disease-causing genetic defects

#89
There is more detailed research as to food consumption patterns. Basically fasting for around 16 hours a day is good for health. From the evolutionary perspective--that invested in a human body 200K years--the way we eat today is really broken. And our body can't adapt to a new pattern even during 1000 years. Not to mention like 50. A human body during 200K years was not prepared to eating a lot. It needs to store energy and to use stored energy. That's a natural cycle and different function that our body needs to execute. Nowadays we just store energy 24/7.

"Emerging findings from studies of animal models and human subjects suggest that intermittent energy restriction periods of as little as 16 h can improve health indicators and counteract disease processes. The mechanisms involve a metabolic shift to fat metabolism and ketone production, and stimulation of adaptive cellular stress responses that prevent and repair molecular damage."

Here is the link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250148/

Also here are patterns of daily and weekly food consumption from this research: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250148/figure/...

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