81–90 of 114 posts
I still don't have the words to explain how, but I insist that psilocybin played a major role in the most successful period of my life. I am generally a highly skeptical person and remain a little frustrated that I can't articulate better such an impactful correlation.
Assuming that psilocybin is effective at treating depression, I find myself wondering whether actual conscious experience (that is, being high) is an essential part of its effectiveness or not. To put this another way, imagine someone takes whatever dose of psilocybin and then is rendered unconsciousness until the perceptual effects wear off. Will there be any difference in its effectiveness as a treatment for depres…
This is not surprising if you've taken it before. It's the experience itself that's liberating, much in the same way that other profoundly meaningful experiences in life depend on you actually "being there" to have any benefit.
Is Psilocybin and/or Ayahuasaca and/or any other DMT source legal anywhere in the world? I would expect at least _some_ places make it legal, possibly have hundreds/thousands of years of experience that might be interesting to read alongside modern studies.
Earlier quoted context omitted.
I believe the ketamine anti-depressant experiments use a different anesthetic to put subjects under in order to split the trip experience from the lower-level chemical effects, and still find benefits. If the trip itself is not necessary for ketamine, that makes it more plausible that it's not necessary for psilocybin etc. (Of course, this doesn't rule out the possibility that much of the benefit is coming from after…
Ketamine is used as a disassociative, though.
Earlier quoted context omitted.
well, in these studies, we are talking about really low doses. so no, "trip"
The present study focused on changes in brain function before versus after psilocybin in patients with treatment-resistant depression who received two doses of the drug (10 mg followed by 25 mg, one-week apart) as part of an open-label clinical trial. 25mg of pure psilocybin, the equivalent of 3.3 - 5 grams of dried mushrooms (depending on strength), is certainly enough for a trip.
Earlier quoted context omitted.
Being conscious during the trip is an essential part of the healing process. In fact, healing comes from the realization of what consciousness really is, that death is not the end, how my little self is just a stubborn part of a larger infinite consciousness that is the Universe thinking itself into existence, etc. You 'remember' what you really are and that's liberating. One theory that I subscribe to is that the dr…
You speak such obvious bullshit, and yet with such authority. You don't have evidence of any of the things you just said.
Whether or not they're true objectively doesn't really matter if the participants believe them to be true.
If they believe those ideas to be true, and that belief is what causes the improvement (similar to how "finding religion" helps people), is that not enough?
Although I do agree that obviously just because they've internalized this experience, that doesn't make it objectively true.
My girlfriend has treatment resistant depression. Most of her life doctors prescribed SSRI based drugs which didn't really work. A lot of money was also spent on psychiatrist for CBT. Based on a youtube videos and blogpost, read about 5HTP. I think 5htp supplements really works in cases where depression is genetic or the depression exists since childhood, where the cause of depression is not known. You can actually s…
Earlier quoted context omitted.
Being conscious during the trip is an essential part of the healing process. In fact, healing comes from the realization of what consciousness really is, that death is not the end, how my little self is just a stubborn part of a larger infinite consciousness that is the Universe thinking itself into existence, etc. You 'remember' what you really are and that's liberating. One theory that I subscribe to is that the dr…
You speak such obvious bullshit, and yet with such authority. You don't have evidence of any of the things you just said.
Does that make it more palatable?
Assuming that psilocybin is effective at treating depression, I find myself wondering whether actual conscious experience (that is, being high) is an essential part of its effectiveness or not. To put this another way, imagine someone takes whatever dose of psilocybin and then is rendered unconsciousness until the perceptual effects wear off. Will there be any difference in its effectiveness as a treatment for depres…
There's good evidence that the degree to which a person has a "mystical-type experience" is a good predictor of the benefit. This is not surprising if you've taken it before. It's the experience itself that's liberating, much in the same way that other profoundly meaningful experiences in life depend on you actually "being there" to have any benefit.
Earlier quoted context omitted.
You speak such obvious bullshit, and yet with such authority. You don't have evidence of any of the things you just said.
Consider it a neurochemical hack that reliably induces certain perceptual shifts. Those shifts in turn can help stabilize various emotional disequilibria. Does that make it more palatable?