Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

How long til we're all on Ozempic?

asteriskmag.com

Post reply on HN
Print view View original

721–730 of 1001 posts

Re: How long til we're all on Ozempic?

#721

Post by phil21 »

pedalpete wrote: post #714
robohydrate wrote: post #299

I've been on tirzepatide (Mounjaro) for 4 months now. I'm down 13% of my body weight. I realized that frequent cannabis consumption interferes with the weight loss, so I've kicked the habit from daily to occasionally on weekends. I've started walking 2-3 miles a day, 2-3 days a week regularly, in addition to eating less and being more motivated to calorie count. All this to say, this drug has been life changing for m…

Have you been recommended an exercise regimen, or taken one up yourself? The one the great things about GLP-1s is that with the weight loss, it's easier to be more active once you've lost some of the weight. The negatives is that the current breed promote a loss in muscle mass as well as fat loss, so it is very important to do your best to maintain if not increase muscle while on them. The next generation of drugs ar…

None of the GLP1s cause more muscle loss than simply losing the same amount of weight without it. It’s the rapid weight loss without resistance training that causes it.

If you calorie restricted with the same exercise routine without the drug you’d see the same amount of lean muscle mass loss as you would taking the drug. This spreading of misinformation is actively harming people.

Re: How long til we're all on Ozempic?

#722

Post by Wytwwww »

acabal wrote: post #276
gcr wrote: post #229

Earlier quoted context omitted.

If you have an open mind, I'd like to assign you some homework if you like. Take a look around r/zepbound and count the following: 1. Posts from folks who diet+exercise, or who have tried diet/exercise and nothing's worked so they then turned to Zepbound ("excited to hit the gym," "my diet is finally starting to work with Zepbound" and similar) 2. Posts from folks who haven't tried diet/exercise and turned to Zepboun…

The more important point the comment you're replying to makes is not "what if people could diet and exercise" - i.e. accept the modern American lifestyle as given, plus force yourself to go to the gym and eat chicken and broccoli - but rather that the modern American lifestyle in fundamentally structured to lead to people being overweight. Instead of being forced to drive everywhere for the most basic possible human…

> In old photos you see people in huge crowds in streets as they walked to their everyday errands

Because they were poor and didn't have a choice. Making driving extremely expensive and inconvenient and prohibitively high taxes on processed food etc. might force people to change their lifestyles, I'm just not sure how politically feasible that.

Re: How long til we're all on Ozempic?

#723

Post by asciimov »

0xcde4c3db wrote: post #602

I think we desperately need to answer the question of why GLP-1 agonists are so effective, and particularly whether it's counteracting something in the environment that has been acting to reduce GLP-1 (or other glucagon-related pathway) activity without us realizing it. The obesity data practically screams that something happened in North America ca. 1980 that messed up our metabolisms, and it may have spread to Euro…

Coke and Pepsi started using HFCS in 1980.

I’d be curious about side effects of the Depression and WW2 that took an extra generation to show up.

Re: How long til we're all on Ozempic?

#724

Post by dehugger »

OptionOfT wrote: post #420

As someone who struggled with their weight his whole life, this medication is a god send. My wife and I cook every evening. We never eat food made in a factory. We buy raw products and spend a good amount of time every day cooking them. Every morning I wake up and go on a 5 mile hike. And still weight kept on coming on. Worse yet, I am on ADHD medication, which are amphetamines and actually make you lose weight. Yet.…

Seconding Zepbound, it has been absolutely life changing for me, and not only in terms of weight loss. It's expensive, but I am blessed with a tech salary that can afford it.

Re: How long til we're all on Ozempic?

#725

Post by tightbookkeeper »

phillipcarter wrote: post #694
archsurface wrote: post #601

Earlier quoted context omitted.

You mention types of food but not quantities. A boat load of healthy food is still going to have an effect. Also, I for one don't consider walking to be exercise. It's fake exercise for people who don't like exercise to claim they exercise. My reason is that I cycle for eight months of the year then walk during the rainy months. By the end of the rainy months I get back on the bike and my fitness level is catastrophi…

Can't speak for OP, but generally speaking there's a lot of variability in peoples' perceptions of healthy food and caloric density. For example, a lot of people see nuts as health food, and yet they're some of the most calorically dense foods you can eat! Another example would be to crack open the Ottolenghi cookbook and make the delicious Lamb Siniyah, which among other things calls for a large amount of Tahini mix…

I think healthy/unhealthy food dichotomy is psychologically the same as religious dieting. It fosters feelings of purity, self control, and is a form of in-group signaling.

But our bodies grind down substances to extract calories. It’s a simple mechanism. You can eat McDonalds everyday if you manage intake.

Re: How long til we're all on Ozempic?

#726

Post by Aeglaecia »

gcr wrote: post #229
dfxm12 wrote: post #170

Instead of a system that makes these drug available for purchase, I'd rather live in a system that promotes healthy food and active behavior. Unfortunately, I have to drive everywhere, work too many hours to have free time for recreation and have no idea which government subsidy is going to help big ag likely at the expense of my health. All things being equal, I'd prefer to spend less money on prescriptions and have…

If you have an open mind, I'd like to assign you some homework if you like. Take a look around r/zepbound and count the following: 1. Posts from folks who diet+exercise, or who have tried diet/exercise and nothing's worked so they then turned to Zepbound ("excited to hit the gym," "my diet is finally starting to work with Zepbound" and similar) 2. Posts from folks who haven't tried diet/exercise and turned to Zepboun…

counter hypothesis - the amount of self control exhibited by an average human is insufficient to self regulate when placed into a hyper enriched environment , for example the capitalistic profferings of junk food tv porn etc , we did not evolve around these hyper stimulatory activities, how on earth are we meant to adapt to them? drugs are not an answer, they are another bandaid making someone else money and allowing the underlying wounds to fester, the solution is education and awareness of this fucked up situation

Re: How long til we're all on Ozempic?

#727

Post by tightbookkeeper »

nostromo wrote: post #615
rootusrootus wrote: post #605

Earlier quoted context omitted.

> For the longest time people argued if overweight people ate too much or not. Maybe uneducated people, but when was the last time anyone seriously doubted that excess calories make you fat? For serious people the discussion has always been about how to reduce the calories, because "just eat less" is provably ineffective. Simple minded people continuously suggest otherwise, but data really doesn't support their intui…

It’s never been as black and white as you’re saying. Lot’s of medical practitioners will even advise you that it’s the quality of food you eat, more so than the quantity. Look at all the published research around processed foods and ultra-processed foods. Other nutritionists will advise you that obesity is all about your macros. And that if you want to lose weight you need to increase fat and protein intake and limit…

> it’s the quality of food you eat

What metrics determine quality? How recently were those established?

Re: How long til we're all on Ozempic?

#728

Post by positr0n »

crooked-v wrote: post #195
mritchie712 wrote: post #84

Earlier quoted context omitted.

Has there ever been a case where something like #2 has happened? Don't think you need to worry about that one.

Sure: the popularization of coffee across western Europe in the 1600s and 1700s, and the way it replaced beer as the most common daytime casual drink. Much of the population went from spending all day mildly intoxicated to being mostly sober and with a caffeine pick-me-up.

Do you know if it was really most the population? Or just most of the intellectuals, nobility, bourgeois, etc. Were peasants coffee drinkers?

Re: How long til we're all on Ozempic?

#730

Post by paulryanrogers »

colordrops wrote: post #642
brianmcc wrote: post #610

Earlier quoted context omitted.

>> I scanned, weighed, and measured every single thing I put into my body Not being snarky, but is this truly "better" than a single weekly injection - 10 seconds and done for the week? I do think our wider society sees medications for overeating as "cheating". Perhaps we might benefit from rethinking that.

For preventable diseases in general, prevention and self control should be attempted before medication. There are health benefits besides being skinny, and all medications have side effects. There's nothing inherently wrong with medication, but addressing the root cause should be tried first, and then medication can be introduced if it doesn't work out. It's not an either-or, binary situation.

Self control has gotten harder as the foods on offer have gotten more sugary and dense compared to traditional foods. Produce is also less available and less nutritious than it once was.
Post reply on HN