Live data from Hacker News

Autism's social deficits in animal model are reversed by an anti-cancer drug

sciencedaily.com

71–80 of 105 posts

Re: Autism's social deficits in animal model are reversed by an anti-cancer drug

#72
My child is on the spectrum, but I love him as he is and he is happy as he is. He is funny and quirky, my mother says I was similar as a child.

Plus, he just won his school prize for Year 9 EMITS (STEM) so not sure why I would want to mess with what might make him like that.

Re: Autism's social deficits in animal model are reversed by an anti-cancer drug

#73
post #67

Mostly parents will be into this. No one would do this to themselves as they will have similar feelings as most (they don't want to give up who they are). Wether being on the spectrum has been good or bad for you; it is you. However parents are really great here; they really don't give a crap about their kids feelings they just want the _best_ for him. > What I mean is they don't want to be embarrassed by their child…

I have ADD with autistic traits, and let me tell you from the bottom of my heart that you are wrong that nobody would like to change themselves.

While I love some parts of my personality, I would have happily given some of that up if it meant I could function socially and not get burnt out by trying to simply work a regular job, cook a meal most days, and keep up with the most basic chores.

But yeah, I definitely don't think parents should have any say when it comes to these kinds of medication. As all medication they should only be given to people who suffer.

If you didn't, and don't suffer, you should not have been medicated. I did suffer, I do suffer, and so does my daughter. I would like to have the choice for myself, and her for herself. We waited until she herself recognised that she didn't want the suffering her traits caused her with how the world currently works. Ideally, I would have changed the world for her to not need, or want to change. However, changing the world is rarely a choice we get to make.

Re: Autism's social deficits in animal model are reversed by an anti-cancer drug

#74
post #18

Whoa. Though I often question if society should treat social deficits of autism even if such a treatment is effective without side-effects. Another solution would be for society to be generally more neuro-inclusive. I can't help but wonder if there are synergistic benefits from being able to have different ways of experiencing the world. (I don't have ASD; my step-daughter is on the spectrum).

Treatments should only be administered if the patient suffers themselves, if the patient actually suffers can however be hard to know at times. This can be a tricky balancing act, but one that I think we can figure out.

I would however like to see medications that treats, or are otherwise reversible. Especially for children we should not induce irreversible behavioural changes except possibly if absolutely required, or as a side effect of treating a dire life threatening condition.

Re: Autism's social deficits in animal model are reversed by an anti-cancer drug

#75
post #66

Earlier quoted context omitted.

I think the experience of being a person goes a lot deeper than having any specific personality, if it didn't we wouldn't be sorting traits into good and bad. If not having learned to read has kept someone away from the influences of literature, we could say that it has impacted their personality, but would that be an excuse to never teach them? Some behaviors associated with autism are really results of having less…

I think it depends on the person; but I personally see a lot of people I would identify as high-functioning people on the ASD spectrum working in senior management positions. We are able to be successful exactly because we have learned to expertly regulate our public and private behaviors to be acceptable to the audience. We’re really deliberate about the soft skills stuff because it doesn’t come naturally. We do tha…

> Your image is everything and you have no friends

Don't assume just because that's there and because some people go for it that it's not pathological. Being "good" at that is an oxymoron to me.

Re: Autism's social deficits in animal model are reversed by an anti-cancer drug

#76

Earlier quoted context omitted.

Honest question, what make you think we are still evolving?

Why would you believe otherwise?

There is no evolutionary pressure.

Evolution is not an endless race to a superior form: mother nature is content with "good enough". Many modern sharks arrived 100 million years ago while modern humans are believed to be 70,000 years old. Why? Sharks were good enough.

Humans are good enough now. Even weak people can survive just fine - even people with defective genes that would not survive enough to reproduce a century ago. Not only dumb people can survive but there are evidence they procreate a lot more than smart people.

I'm just playing the devil's advocate.

Re: Autism's social deficits in animal model are reversed by an anti-cancer drug

#77
post #54

Earlier quoted context omitted.

I have ADHD. Drugs like ritalin never "fixed" me. They basically allowed me an exchange: give up the charisma, personality, sociability, and appetite for 8 hours of being able to focus on something. I won't write an essay here but trust me that the two versions of me were day and night and both had significant benefits and challenges. I really struggled growing up. By the time I got to college I learned to use the dr…

> give up the charisma, personality, sociability, and appetite for 8 hours of being able to focus on something Perhaps this autism treating drug is like an anti-Ritalin: give up the intense focus, and in exchange get charisma and sociability.

If I could undo whatever 8 years of concerta did to my brain (and start growing like a kid again where I left off), I would give my life earnings for that.

Re: Autism's social deficits in animal model are reversed by an anti-cancer drug

#78
post #54

Earlier quoted context omitted.

> give up the charisma, personality, sociability, and appetite for 8 hours of being able to focus on something Perhaps this autism treating drug is like an anti-Ritalin: give up the intense focus, and in exchange get charisma and sociability.

If I could undo whatever 8 years of concerta did to my brain (and start growing like a kid again where I left off), I would give my life earnings for that.

Could you elaborate?

Re: Autism's social deficits in animal model are reversed by an anti-cancer drug

#79
post #16

As someone on the spectrum, I don’t necessarily know if this is something I would want. My ASD is a big part of my personality; if these social “difficulties” (which really just mean I click with a different type of person) were “solved” I don’t know I would be the same person. Maybe this can offer some hope for others with more profound issues, but if you’ve found a way to function in society I’m not sure this will…

I have ADHD. Drugs like ritalin never "fixed" me. They basically allowed me an exchange: give up the charisma, personality, sociability, and appetite for 8 hours of being able to focus on something. I won't write an essay here but trust me that the two versions of me were day and night and both had significant benefits and challenges. I really struggled growing up. By the time I got to college I learned to use the dr…

How sporadically did you use ritalin? I think there's a risk of developing dopamine sensitization with infrequent use.

Re: Autism's social deficits in animal model are reversed by an anti-cancer drug

#80
post #16

As someone on the spectrum, I don’t necessarily know if this is something I would want. My ASD is a big part of my personality; if these social “difficulties” (which really just mean I click with a different type of person) were “solved” I don’t know I would be the same person. Maybe this can offer some hope for others with more profound issues, but if you’ve found a way to function in society I’m not sure this will…

I have ADHD. Drugs like ritalin never "fixed" me. They basically allowed me an exchange: give up the charisma, personality, sociability, and appetite for 8 hours of being able to focus on something. I won't write an essay here but trust me that the two versions of me were day and night and both had significant benefits and challenges. I really struggled growing up. By the time I got to college I learned to use the dr…

Side question for my research: Have you tried hiking for more than 10 consecutive days, possibly without carrying tech with you?
Post reply on HN