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How long til we're all on Ozempic?

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Re: How long til we're all on Ozempic?

#671
post #42

Earlier quoted context omitted.

Yes, because what obese people lack is education.

From my subjective experience in life, what they very often lacked was parents who set the right examples around food. I know that doesn't apply to everyone of course, but I've witnessed it time and time again - an upbringing with deeply disordered routines/practices around food. It's universal among obese people in my life. I speculate that better awareness of diet/nutrition might help to prevent passing on such beh…

> From my subjective experience in life, what they very often lacked was parents who set the right examples around food.

No amount of education will change who your parents were or how you were raised. Have you observed a strong correlation between how well educated someone is vs. obesity?

> I speculate that better awareness of diet/nutrition might help to prevent passing on such behaviours, like not feeding the family exclusively a bucket of KFC or McDonalds, or using food as a reward, etc. etc.

I'd encourage you to talk to any reasonably intelligent obese parent to see if they need better awareness of diet/nutrition. Better still, do a survey of obese and non-obese people to compare awareness of diet/nutrition between the two groups.

> I mean, medication won't actually solve what is caused by behaviour, right?

Saying that obesity is caused by behaviour and therefore can't be solved with medication is a bold statement to make in the context of a story about a drug that has been clinically proven to help obese people to lose weight.

Medication is often prescribed to help people who suffer from behavioural problems with positive results. I wouldn't presume medication can solve all problems caused by behaviour, but there is empirical evidence that for some problems it does help. As near as we can tell, human behaviour is regulated by a electrochemical brain & nervous system. Dumping chemicals into that system can of course change human behaviour. We see evidence of that (for better or for worse) all the time. If you have doubts and you don't even need to get a prescription, try taking a hit of acid/cocaine/alchohol and see if behaviour changes.

> If parents know their habits around food are basically ensuring their kids will struggle with obesity, maybe they'll make the effort to do something different?

The US has had a dramatic increase in obesity within a single generation (as in, people who were not obese for much of their lives have become morbidly obese at a rate far exceeding previous generations), let alone cross generational. While food/nutrition/health habits can certainly have a profound effect on someone's weight, there are clearly other factors at play.

Consider, for a moment, the reality of an obese person living in the US today. You get negative feedback about your weight all the time. You suffer negative social outcomes, let alone all the physical ones, so few, if any, want to be obese. There is no lack of motivation to seek out information on how to avoid being obese. There's a $300+ billion industry diet/health/nutrition industry constantly seeking to inform you about products they offer to help with your diet/health/nutrition... and that's not counting the doctors that you are no doubt interacting with regularly. Of course, that's not counting all the education (solicited or otherwise) you get from friends, family, acquaintances and even random strangers. It's hard to get through a day without being "educated" about diet, nutrition and health.

There's a cultural bias to think the problem is simply about behavioural/willpower/education, much the same way we look at poverty. It demonstrates a profound lack of understanding of and empathy for the plight of people who are suffering from obesity.

Re: How long til we're all on Ozempic?

#672
post #658

Earlier quoted context omitted.

I run three miles a day, never drive anywhere (bike or bus), eat reasonably healthy, and I'm still 20 pounds overweight. And what really scares me is that running is the only exercise I enjoy and if my weight fluctuates up just 5 pounds or so, I start getting hip/knee/foot etc pain. If I gain 10 pounds through some lapse in morality, I won't be able to run anymore and I'm cooked. If that happens, I'm banging down my…

So I'm a distance runner, who is on these drugs.. and yeah, It sucks, I LOVE running.. but running heavy SUCKS. Most people run to lose weight, I lose weight to run.

honest to god i wish i knew what it was like to be like you —i have always hated every step of a run, and im halfway convinced the notion of a runners high is a convenient fiction cooked up by nike.

Re: How long til we're all on Ozempic?

#673
post #643

I think we desperately need to answer the question of why GLP-1 agonists are so effective, and particularly whether it's counteracting something in the environment that has been acting to reduce GLP-1 (or other glucagon-related pathway) activity without us realizing it. The obesity data practically screams that something happened in North America ca. 1980 that messed up our metabolisms, and it may have spread to Euro…

One aspect is that the US food system as a crap ton of UPF.

UPF means "ultra-processed foods", in case anyone else had to look it up like I did.

Re: How long til we're all on Ozempic?

#674

Earlier quoted context omitted.

It’s been studied pretty well. Possible effective solutions to the US obesity epidemic are pretty much limited to: 1) Radically alter aspects of food culture, work culture, social policy, and business regulation. 2) Magic pill (/injection) There appears to be no imminent progress on the many parts of #1 that need serious work, so if we want a big turn-around in the next half-century, #2 has suddenly and surprisingly…

> Possible effective solutions to the US obesity epidemic Just wanted to mention that this is not a US problem, and framing it as such won't help find solutions. Even in southeast Asia the rates over obesity are steadily increasing. Europe is already much fatter than southeast Asia. This is a worldwide phenomenon.

USA is the worst by a long stretch. I believe it's 80% of the USA population that is overweight.

Being fit there is statistically considered an anomaly.

I don't know of any other country where you would be weird because you're fit.

Re: How long til we're all on Ozempic?

#675
post #573

I've been on tirzepatide (Mounjaro) for 4 months now. I'm down 13% of my body weight. I realized that frequent cannabis consumption interferes with the weight loss, so I've kicked the habit from daily to occasionally on weekends. I've started walking 2-3 miles a day, 2-3 days a week regularly, in addition to eating less and being more motivated to calorie count. All this to say, this drug has been life changing for m…

Cut on carbs and you will have all the benefits without the nasty side effects. Check https://metabolicmind.org for details. My own experience with the keto diet - https://www.feelingbuggy.com/p/finding-hope-after-decades-of...

This is true, but fat people have a hell of a time cutting out all carbs. For many of them, they'll eat the "low carb" option, and then have an occasional binge and it negates any benifits of low carb, and doesn't put them in ketosis, etc.

I strictly maintain my weight. If I catch it going over over 155# (I'm a 5'10" 61 year3 old male) I'll do a strict cut. And I know that either strictly counting calores OR going to as close to zero carbs will have the same net effect.

But a person who has obesity or is overweight will not be able to follow a diet. They are just incapable of doing so, or will lie to themselves or others about it and claim it's their "metabolism" or a medical condition, etc.

Re: How long til we're all on Ozempic?

#676

So basically eat shit and then take drugs to lose the weight you accumulated because of your bad diet ?? Am I the only one to realize how this is so wrong? You would think When a pipe leaks, you fix it. You're not going to put a basin under it, empty it every day, pay for a new basin every few week and continue to have your damn pipe leak. Oh man... If only you could teach people how to eat better instead.

> Am I the only one

No, definitely not. There's a few of you in this discussion.

Re: How long til we're all on Ozempic?

#677
post #588
post #381

Earlier quoted context omitted.

My view about obesity has shifted dramatically since Ozempic came out. Before this, I didn't think about it too much (I am not obese myself). I notice now that there is a LOT of judgement, bias(?), around obesity, that people, obese or not, carry with them [1]. I certainly carried that bias, and the reason I noticed it was because Ozempic is literally an external substance that you take that simply makes obesity go a…

Personally, I've never seen obesity as a failure of character or willpower, at least as long as I can remember having any particular views on it at all. I see it as a failure of information and choices. Obesity was rare until the United States officially decided in 1977 that saturated fats were considered harmful. A few years later, it started rising to the current epidemic level. We've come a long way since the Amer…

Do you view a chronic smoker as a failure of character or willpower?

Re: How long til we're all on Ozempic?

#678

Earlier quoted context omitted.

Just eat regular food. Hardly anything in my diet would be mysterious to a time traveler from 100 years ago, or indeed 200 years ago. Occasionally I enjoy chocolate or instant noodles but mostly it's just fruit, veg, meat, dairy, and grains. If you don't know what something is made out of or how, then don't eat it.

Not a panacea. I stay fat no problem without junk food. Processed foods make me ill, so I make almost all my own meals from whole ingredients. Too many calories is too many calories no matter how you get it. I'm a pretty good cook, though.

Obviously one should not eat too much, but I was responding specifically to the comment about the industrial revolution leading to engineered foods full of empty calories in the grandparent comment. I would personally like to see such food regulated mostly out of existence, but in the meantime I just encourage people not to eat it.

Re: How long til we're all on Ozempic?

#679
post #287

Earlier quoted context omitted.

GP isn't talking about self-control, they're talking about the fact we've created a system that requires obscene amounts of self-control if you wish to maintain physical health. People in the 50s weren't slimmer because they had ironclad determination to stay such.

Exactly, good systems do not rely on willpower. They rather make obvious habits effortless. Deviating from the mean is hard. Bad food and sedentarism are the norm.

The amount of food you eat isn't a habit. And I don't know what it is that makes people obese, but I don't think it's simply "bad food" as in the stereotype of bad food.

It seems clear enough to me that there is something - something - in the ecosystem that messes up the body's weight / energy homeostasis and we haven't identified the culprit. It might be a food additive, but it could be something to do with artificial light in the evening or plasticizers in our plastic products or who knows what.

Just my pov as non-overweight person who doesn't exercise (other than flipping my four year old around), doesn't walk or run long distances (but a 5 mile walk every couple of months doesn't phase me), eats very few fruits and vegetables, generally eats mostly meat, pasta, bread, cheese, cream and potatoes, and ends up in a fast food outlet maybe once a week on average.

Re: How long til we're all on Ozempic?

#680

As someone who struggled with their weight his whole life, this medication is a god send. My wife and I cook every evening. We never eat food made in a factory. We buy raw products and spend a good amount of time every day cooking them. Every morning I wake up and go on a 5 mile hike. And still weight kept on coming on. Worse yet, I am on ADHD medication, which are amphetamines and actually make you lose weight. Yet.…

Perhaps the first person on HN who actively and without shame pays attention to the fact that Adderall is a very nice amphet cocktail. Surprising though you don't loose wait with it, sad also given the circumstances. But I envy you a little cause such ADHD boost is only illegal in EU.

Sometimes I wonder if it was a some neat trick by US gov to diagnose and put 1/5 of the population on amphetamines (2024 data +60mil prescriptions of Adderall), so that most everyone who is actually like smart or sensitive or anything of value to the industry, can (almost) freely microdose on it and as a result increase productivity.

Which... means 1/5 of the population suddenly increases output. Perhaps we all'd be on Aderall at some point, dunno bout the Ozempics...

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