I wonder if there is any relation to the odorous biomarker that dogs can sniff out in Parkinson’s patients: https://pubmed.ncbi.nlm.nih.gov/36054272/
Significant breakthrough in search for Parkinson's biomarker
61–70 of 196 posts
Re: Significant breakthrough in search for Parkinson's biomarker
#62Earlier quoted context omitted.
No way. About five years ago there was a quack-y study about reducing death in sepsis which called for high-dose vitamin C, thiamine and steroids. None of these are patent protected. The first study purported to show a 100% reduction in mortality. There were many RCTs done after this which did not bear out the effect, and it has now essentially been proven to be ineffective. it is possible to fund studies without ind…
Who actually thought that steroids help with an infection? Don't those usually make you more susceptible?
"Multiple randomized trials indicate that systemic corticosteroid therapy improves clinical outcomes and reduces mortality in hospitalized patients with COVID-19 who require supplemental oxygen, presumably by mitigating the COVID-19-induced systemic inflammatory response that can lead to lung injury and multisystem organ dysfunction."
https://www.covid19treatmentguidelines.nih.gov/therapies/imm...
But yes, you're also right that it usually makes you more susceptible to infection because your immune system isn't working as hard.
Re: Significant breakthrough in search for Parkinson's biomarker
#63Earlier quoted context omitted.
No way. About five years ago there was a quack-y study about reducing death in sepsis which called for high-dose vitamin C, thiamine and steroids. None of these are patent protected. The first study purported to show a 100% reduction in mortality. There were many RCTs done after this which did not bear out the effect, and it has now essentially been proven to be ineffective. it is possible to fund studies without ind…
Who actually thought that steroids help with an infection? Don't those usually make you more susceptible?
Re: Significant breakthrough in search for Parkinson's biomarker
#64I just found out about Thiamine (vitamin B1) megadose therapy for Parkinson's: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762356/ Another study: https://pubmed.ncbi.nlm.nih.gov/26505466/ > Conclusions: Administration of parenteral high-dose thiamine was effective in reversing PD motor and nonmotor symptoms. The clinical improvement was stable over time in all the patients. From our clinical evidence, we hypothesiz…
Published in the "Journal of Integrative and Complementary Medicine", "The leading peer-reviewed journal providing scientific research for the evaluation and integration of complementary medicine into mainstream medical practice." "Integrative and Complementary Medicine" is a fancy way of saying quackery. Also, the video you linked to is on a channel run by a person describing himself as "a certified functional medic…
Re: Significant breakthrough in search for Parkinson's biomarker
#65I just found out about Thiamine (vitamin B1) megadose therapy for Parkinson's: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762356/ Another study: https://pubmed.ncbi.nlm.nih.gov/26505466/ > Conclusions: Administration of parenteral high-dose thiamine was effective in reversing PD motor and nonmotor symptoms. The clinical improvement was stable over time in all the patients. From our clinical evidence, we hypothesiz…
> 100 mg of thiamine administered intramuscularly twice a week Is it possible to get anywhere near this much with dietary thiamine?
Re: Significant breakthrough in search for Parkinson's biomarker
#66Earlier quoted context omitted.
>This is likely on the same level as horse dewormer for COVID You mean something that's demonstrated to have a statistically significant protective effect in a majority of studies but was attacked mercilessly by the pharma industry and the media they fund because they can't profit from a generic drug like that? https://c19ivm.org/meta.html
Looks great .. dive in (talk to your local professional epidemiologist) and it's a skewed collection of low N studies mixed in with studies in regions with large intestinal parasite issues. Does horse dewormer do anything significant for large populations in first world countries? No. ( Save for regions with a intestinal parasite problem ) Elsewhere it gets rid of a significant number of parasites, making people heal…
Re: Significant breakthrough in search for Parkinson's biomarker
#67I just found out about Thiamine (vitamin B1) megadose therapy for Parkinson's: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762356/ Another study: https://pubmed.ncbi.nlm.nih.gov/26505466/ > Conclusions: Administration of parenteral high-dose thiamine was effective in reversing PD motor and nonmotor symptoms. The clinical improvement was stable over time in all the patients. From our clinical evidence, we hypothesiz…
If this Was discovered 10 years ago, I’m assuming it must be fairly limited in helping, or the results haven’t lasted or something?
Re: Significant breakthrough in search for Parkinson's biomarker
#68Re: Significant breakthrough in search for Parkinson's biomarker
#69Earlier quoted context omitted.
Looks great .. dive in (talk to your local professional epidemiologist) and it's a skewed collection of low N studies mixed in with studies in regions with large intestinal parasite issues. Does horse dewormer do anything significant for large populations in first world countries? No. ( Save for regions with a intestinal parasite problem ) Elsewhere it gets rid of a significant number of parasites, making people heal…
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In the case of COVID in populations sans those conditions .. not so much.
Re: Significant breakthrough in search for Parkinson's biomarker
#70Earlier quoted context omitted.
Looks great .. dive in (talk to your local professional epidemiologist) and it's a skewed collection of low N studies mixed in with studies in regions with large intestinal parasite issues. Does horse dewormer do anything significant for large populations in first world countries? No. ( Save for regions with a intestinal parasite problem ) Elsewhere it gets rid of a significant number of parasites, making people heal…
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