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Long Covid: major findings, mechanisms and recommendations

nature.com

61–70 of 229 posts

Re: Long Covid: major findings, mechanisms and recommendations

#61

Earlier quoted context omitted.

Significantly worse than the flu - multi systemic organ damage. The narrative that covid is like the flu, is both wildly inaccurate as this paper explains, and also dangerous, leading to a more cavalier attitude towards covid prevention.

There was a flu pandemic 100 years ago which killed 21 million.

The comparison is to current strains of influenza. There could also be a much worse coronavirus 100 years from now.

Re: Long Covid: major findings, mechanisms and recommendations

#62
post #8

Earlier quoted context omitted.

> Can anyone more medically and scientifically literate provide some context to temper my doom and gloom? Most of these issues stem back to endothelium damage. And the good news is that, in addition to taking all the vaccines you're eligible to get, there are a bunch of other things you can do to strengthen and protect your endothelium, e.g. doing HIIT and taking ACE inhibitors. The one risk we (afaik) don't really k…

Except for me and many others long covid symptoms got worse after vaccination. Additionally new research is uncovering serious and significant risks for the vaccine with fairly marginal protection benefits.

I suffered severe depression after getting the J&J vaccine - it wasn't even an mRNA vaccine. It became significantly harder to code and my brain felt like it had been dragged across concrete. Later it'd be stinging and I was dry heaving. Not fun.

I hate to ask - but what sort of research is available so far?

Re: Long Covid: major findings, mechanisms and recommendations

#64
post #15
post #5

As always, it is difficult to assess this sort of thing without a reference to the flu. As far as I can tell, in daily life we are continuously encountering people with various chronic problems and systemically under-calling the impact of them. It is a total coincidence if a body is functioning at full capacity. If COVID increases the hazard ratios there isn't much I can do. As far as I can tell, everyone is going to…

> As far as I can tell, everyone is going to get COVID This is a common feeling, but remember: You can greatly affect the probability of an infection through precautions. And if unlucky, you can greatly affect the number of times you get infected through precautions. Fewer infections, fewer rolls of the dice. As far as I'm aware, I'm still infection free and hope to remain so. I am in a much better situation than mos…

Pre-pandemic, I used to get sick about half the time I traveled. I've flown five or six times in the past couple years, and with proper FFP2 mask usage, I've been completely fine.

Most people here are privileged enough to not work a service job or anything like that, so you do in fact have the opportunity to drastically reduce your likelihood of contracting contagious diseases.

Re: Long Covid: major findings, mechanisms and recommendations

#65
post #2

Interesting that they classify loss of smell as a neurological symptom. I had Covid last January and my sense of smell has never been the same. I used to be able to walk into a room, flair my nostrils, and pick up everything from the couch, carpet, and curtains… to the subtle cool drafts from the windows and fireplace. Now everything has completely dulled out, and I only occasionally pick up those old scents in passi…

I was confused by this, but I think they mean "neurological" as in "relating to the nervous system," specifically to the olfactory sensory neurons that detect smells.

Re: Long Covid: major findings, mechanisms and recommendations

#66

Covid fatigue is no joke. As an Elite Athlete I'm training 20-30 hours a week. I got covid last year (triple vaxed) and it wiped me out for a good 6 months. It took me 3 weeks to be able to walk longer than a minute without needing to lay down for the rest of the day and sleep. I have dealt with fatigue problems for 6 months and only just now, do I feel like I'm getting "back to normal". The most frustrating thing is…

That sucks. My experience was to get back to training fairly soon (2 weeks after fever went away). After that training session I knew I should rest more and took an additional 2 weeks off. Then built back up my regular training starting at 10% volume and increasing at 10% increases each week. After 3 months I was back to regular volume. My suggestion is that everyone take at least two weeks off, and build up volume v…

It's kind if important whether you develop long covid or not. If you don't then you don't need a long break, if you do, you could be out for months or forever.

Re: Long Covid: major findings, mechanisms and recommendations

#67

Earlier quoted context omitted.

Except for me and many others long covid symptoms got worse after vaccination. Additionally new research is uncovering serious and significant risks for the vaccine with fairly marginal protection benefits.

[flagged]

Incorrect, people contracted long covid before vaccines were available.

Re: Long Covid: major findings, mechanisms and recommendations

#68
post #4

Unease and woe are the two feelings I'm left with after my quick layman reading of the article. Think I am most concerned with the reproductive implications, which seem under researched. Coupled with the unrelated decline in sperm count the past decade... I'm hoping my ruminations are just me catastrophizing. Can anyone more medically and scientifically literate provide some context to temper my doom and gloom?

Covid infection outcomes exist on a continuum from death to harmless. There is also "long-flu", and I'm sure there are persistent responses to other respiratory viruses, so long covid isn't totally novel. If you're scared for your health the best thing you can do is be healthy, eat right, exercise, don't smoke, etc.

That’s all good advice in general, but it also doesn’t seem to have much bearing on who gets long covid - plenty of elite athletes have contracted long covid.

Re: Long Covid: major findings, mechanisms and recommendations

#69
post #15
post #5

As always, it is difficult to assess this sort of thing without a reference to the flu. As far as I can tell, in daily life we are continuously encountering people with various chronic problems and systemically under-calling the impact of them. It is a total coincidence if a body is functioning at full capacity. If COVID increases the hazard ratios there isn't much I can do. As far as I can tell, everyone is going to…

> As far as I can tell, everyone is going to get COVID This is a common feeling, but remember: You can greatly affect the probability of an infection through precautions. And if unlucky, you can greatly affect the number of times you get infected through precautions. Fewer infections, fewer rolls of the dice. As far as I'm aware, I'm still infection free and hope to remain so. I am in a much better situation than mos…

[deleted]

Re: Long Covid: major findings, mechanisms and recommendations

#70
post #42

Earlier quoted context omitted.

Except for me and many others long covid symptoms got worse after vaccination. Additionally new research is uncovering serious and significant risks for the vaccine with fairly marginal protection benefits.

> Additionally new research is uncovering serious and significant risks for the vaccine with fairly marginal protection benefits. Could you provide a link to that research ?

https://www.sciencedirect.com/science/article/pii/S0264410X2...

https://jackanapes.substack.com/p/cdc-finally-released-its-v...

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