Earlier quoted context omitted.
Yeah, timezones (and different days) are an issue for regular meetings. At my last job, US east coast to Europe worked pretty well. We'd be reasonable morning time on the east coast and Europe would be reasonable mid to late afternoon time. But the (for me occasional) call to Singapore was always a pain for someone.
I found being in the US east coast in teams spread across Europe and the US to have the advantage of being able to touch base with anyone fairly easily but the disadvantage of never getting that natural quiet period. I don’t see how us east cost apac is really feasible on any kind of regular basis.
Up to 5 or 6 hours is a reasonable range for routine interactions.