Sometimes they're smaller impacts - like the ability to only enable GPS when an App is actively being used. Other times they are larger - like the the changes to the Advertising and Device IDs.
I've read here that the loss of the singular, centralized and controlled store could potentially be an issue for things like malware, privacy, and some of the other causes Apple has come out to fight for on behalf of the user. Perhaps Apple forgot to consider its own behavior as a threat to those ideals? Could Apple have avoided all of this if they applied the principles they used in other cases to themselves?
If the store had a 12% rate would Epic have bothered to do this? Other decisions can come into play too, like no ability for upgrade pricing and how subscrption costs are handled. If we really look, the list could get long.
I guess what I'm trying to say is if Apple truly cares about the things that could be lost if the App ecosystem is altered, then perhaps it needs to take the same hit it has doled out to others in the name of that cause?