The Charlie Hebdo attacks show that these days, real satire of Islam can't be done without significant risk of violent reprisal. If you doubt that statement, remember The Book of Mormon. (The play, not the actual book.) Could you imagine Trey Parker and Matt Stone making an equivalent Broadway play about Islam? Could you imagine them calling it The Qur'an to Google-bomb the original? Even if they disregarded their ow…
Abortion is obviously not the same thing as a cartoon, but it is a safe, routine, and legal elective medical procedure in the U.S.
Also realize that the vast (i.e. many orders of magnitude) majority of Muslims, while offended by satirical depictions of Muhammed, do NOT resort to violence.
It is the violence, and threats of violence--not the offense--that is the problem. Plenty of people take strong offense at things that seem silly to other people; for example, over software libraries to initialize Linux-based operating systems (init.d vs systemd). Or mobile device app store rules.
And finally before we all jump on our high horse about religion, remember that there are plenty of examples of violent threats within our own industry--say, for tweeting about a sex joke at a software conference, or complaining about videogame reviews.