Here are some points about pickups that appeal to me and maybe to others:
(1) Bumpers. Pickup trucks (PUTs) tend to have actual, steel bumpers (often chrome plated which indicates that they are steel), both front and rear. Passenger cars have, instead, plastic over some structures for crumple zones or some such. So, if run into something, say, a deer crossing the road in the middle of the night, then are better off with the bumpers; the plastic and crumple zone is less rugged and more subject to expensive damage. Bumpers can be useful otherwise, say, wrap and hook on with a steel cable and pull or be pulled.
(2) Passenger cars emphasize smooth ride. So, the springs and shocks tend to be soft. On PUTs, the springs and shocks are stiff enough to do well carrying heavy loads over rough ground. So, (i) the springs on both passenger cars and PUTs are usually spring steel with a not very long fatigue life, say, under 100,000 miles. Having the springs suffer from metal fatigue and sag is a bummer. The stiffer springs in a PUT flex less and so fatigue less and even when fatigued still have enough stiffness not to sage. (ii) Over rough surfaces, soft springs and shocks more easily bounce around and bottom out -- not good.
(3) In addition to the springs, PUTs have suspensions better able to take loads and bumps and, thus, last longer. E.g., in the front, passenger cars, again, emphasizing smooth ride, have soft suspension bushings, soft stabilizer bars and mounts for them, soft shocks, and struts instead of just A-frames -- the PUT suspensions last longer. In the rear the PUTs have leaf springs with extra leaves for heavy loads instead of coil springs common in passenger cars -- the stiff leaf springs last longer before sagging or actually breaking than the soft coil springs.
(4) PUTs have more ground clearance. So, e.g., if there is a traffic jam, when in a PUT might just head for a curb or a ditch, cross some rough ground, head in a different direction, and avoid the jam. At times extra ground clearance is darned nice to have.
(5) To exaggerate, PUTs are for people in work clothes with mud on their shoes, and passenger cars are for suits and evening gowns with spotless shoes. More generally the interiors of PUTs are more rugged, aimed at utility instead of luxury.
(6) PUT brakes have to be strong enough to stop the truck when it also has a big load, say, 1000+ pounds. This means that with light loads, the brakes will last longer.
(7) PUTs have more head room in the door openings and the interiors. Tall people have an easier time getting in and out.
(8) PUTs are commonly well designed for towing; for most passenger cars, towing is less advisable. Towing requires, yes, a trailer hitch but also connections for lights and maybe brakes on the trailer, a stronger transmission, a larger engine radiator, etc.
(9) A lot of small passenger cars have front wheel drive, and PUTs have rear wheel drive as the main drive with a solid axle which mechanically simpler, more rugged, and lasts longer.
In short, PUTs emphasize utility and passenger cars, luxury.
Similarly much of the US is big on blue jeans -- utility over luxury. Blue jeans are made of essentially the same canvas that was used for sails on sailing ships and, thus, is one of the toughest cotton fabric weaves there is; the seam sewing is very strong, and some stress points have brass rivets.