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Had Covid? You’ll probably make antibodies for a lifetime

nature.com

301–310 of 426 posts

Re: Had Covid? You’ll probably make antibodies for a lifetime

#301
post #207

I know two people who had covid and who right now have a second covid infection by the british mutation. One of them also had their first vaccination.

>I know two people who had covid and who right now have a second covid infection by the british mutation. One of them also had their first vaccination. As of today, there are only 84 confirmed cases of reinfection worldwide, with three deaths. https://bnonews.com/index.php/2020/08/covid-19-reinfection-t...

Published 9 months ago.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#302
post #278
post #261

Earlier quoted context omitted.

> It almost seems like a lot of people don't want the data to indicate that natural immunity is strong and long lasting, even though the data shows that reinfection is extemely rare. I too remember when the concept of "natural immunity to Covid" was a wild, dangerous conspiracy theory, along with the "came out of the Wuhan lab" theory. Funny watching the narrative change in real time.

They probably just don't want a repeat of the mis-steps that characterized early covid response. Early information changed a lot and resulted in distrust, and poor adherence to recommended measures. Rolling back precautionary measures is a one time thing. They don't get to say "hey we messed up, put those masks back on" because nobody will comply. It just makes sense to come up with a sure consensus before natural im…

China wants to hide their own faults. Everything they do supports this narrative. To lose face might mean an end to power. Reforms are only possible by pointing likely theories because the proof is gone and it happened months before the outbreak was even registered.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#303

And every new study like this confirms we didn’t know enough about it to propose solutions like “herd immunity”

Herd immunity seems like a default assumption?

At worst, we will always end up with the herd immunity solution. Others need to prove themselves to be more effective

Re: Had Covid? You’ll probably make antibodies for a lifetime

#304
post #263

It almost seems like a lot of people don't want the data to indicate that natural immunity is strong and long lasting, even though the data shows that reinfection is extemely rare. Similar to how so many people have been unwilling to even consider a lab leak was a possibility, until just now it seems, because that idea was heresy to the orthodox dogma that ordained Scientists are Saviors. Humans have equated sickness…

Sort of. The infectious disease experts I know and worked with this past year are less worried about a political point and more worried that the immunity fades.

They must not think or read very deeply into their own field then, because there exists the phenomenom of immunological memory, ie the effect where memory B/T cells lay dormant in the body for decades, and upon exposure to the characteristic antigen of SARS-2 (in this case) they ramp up antibody production exponentially. This results in - theoretically, but this is definitely what happens - lower peak viral load, lower symptomacity, and thus lower transmission and a shorter disease course.

Thus even when full immunity to reinfection is gone - which btw the estimates I’ve seen are that IgG lasts a few years before the individual is seronegative again - there will still be immunological memory which persists indefinitely and vastly reduces mortality and morbidity.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#305
post #207

Earlier quoted context omitted.

>I know two people who had covid and who right now have a second covid infection by the british mutation. One of them also had their first vaccination. As of today, there are only 84 confirmed cases of reinfection worldwide, with three deaths. https://bnonews.com/index.php/2020/08/covid-19-reinfection-t...

Published 9 months ago.

That's when the article was first published. As it states, it is updated twice a week. Look at the most recent entries.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#306

It almost seems like a lot of people don't want the data to indicate that natural immunity is strong and long lasting, even though the data shows that reinfection is extemely rare. Similar to how so many people have been unwilling to even consider a lab leak was a possibility, until just now it seems, because that idea was heresy to the orthodox dogma that ordained Scientists are Saviors. Humans have equated sickness…

Almost like it's okay to dismiss statements made without ample research and evidence and accept them later when due diligence has been done.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#307
post #263

It almost seems like a lot of people don't want the data to indicate that natural immunity is strong and long lasting, even though the data shows that reinfection is extemely rare. Similar to how so many people have been unwilling to even consider a lab leak was a possibility, until just now it seems, because that idea was heresy to the orthodox dogma that ordained Scientists are Saviors. Humans have equated sickness…

Sort of. The infectious disease experts I know and worked with this past year are less worried about a political point and more worried that the immunity fades.

What always tickles me is if the immunity fades, you get a bout of no taste and smell for a few days, and recover again.

But we aren’t testing as much, so it’ll be worse for those at risk

Re: Had Covid? You’ll probably make antibodies for a lifetime

#308

Earlier quoted context omitted.

The vaccines (so far) all use sequences of the spike protein from an early sample of COVID-19. They just make spike proteins and your body sees it and becomes immune to it. They've made some modifications, but for better stability/structure outside of the virus, but not (yet) to address variants. If anything, infection from current circulating virus is more relevantly effective (but obviously more dangerous than the…

Yes exactly this. Naturalistic immunity learns a more diverse set of epitopes. Whereas the artificial-spike-protein immunity is learning just the S protein. The spike is super important but it’s not the only source of epitopes. And I’ve seen some papers on immunology of SARS-2 that do show a lot of activity that’s not based around the spike protein. This notion that natural immunity is “worse” or won’t be able to han…

[deleted]

Re: Had Covid? You’ll probably make antibodies for a lifetime

#309
post #261

Earlier quoted context omitted.

> It almost seems like a lot of people don't want the data to indicate that natural immunity is strong and long lasting, even though the data shows that reinfection is extemely rare. I too remember when the concept of "natural immunity to Covid" was a wild, dangerous conspiracy theory, along with the "came out of the Wuhan lab" theory. Funny watching the narrative change in real time.

Natural immunity is great. If you survive. And if you don't give it to others. Almost impossible not to give it to others. Relying on it was pretty reckless, especially given how little we understand it.

I don’t think we’re appreciating the nuance surrounding “survived”...anecdotally my partner who worked in a hospital during peak infection has horror stories of “survivors” with debilitating long term effects and unexpected complications with other diseases. Something to consider when we talk numbers.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#310

It almost seems like a lot of people don't want the data to indicate that natural immunity is strong and long lasting, even though the data shows that reinfection is extemely rare. Similar to how so many people have been unwilling to even consider a lab leak was a possibility, until just now it seems, because that idea was heresy to the orthodox dogma that ordained Scientists are Saviors. Humans have equated sickness…

How do you know that reinfection is rare esp for variants? We've been in lock down and meant of those infected self isolate voluntarily or as a consequence of being sick.

And what's the consequence of your pov? That everyone just gets sick and those who make it are all good? What good is public policy if it doesn't protect the public?

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