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Trials on veterans suggest ibogaine could provide a new treatment for PTSD

bbc.com

31–40 of 136 posts

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#31
post #13

I always wonder why ECT doesn't get more press. It very very often works on depression (and bipolar disorder, catatonia; anything affective-related really), although the effects may wane over time when the treatment is discontinued. Memory loss is one of the side effects, and it could actually be beneficial here.

It's strange how much attention novel psychedelic treatments get compared with older, less glamorous interventions that already help a lot of people

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#32

This is, I am assuming from the context, not opporating under the assumption PTSD often is rooted in brain damage from exposure to shockwaves.

PTSD doesn't have anything to do with brain damage.

PTSD is a trauma response.

Are you thinking of TBI? TBI is a cumulative impact of small and large head trauma.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#34
post #14

Does it really help or are they just too dissociated after taking it

As someone who takes antidepressants this is nonsensical to me. I don’t feel 100% normal on an SSRI, I experience the normal side-effects of flat affect and weird tastes, etc. But the alternative is regular panic, exhaustion, indigestion, and general volatility that makes my life difficult and hard for others to interact with me. If dissociation is better than regular PTSD, then go for it. We don’t expect people with…

Exactly this - I don't believe that it's meant to be a "you're now completely fixed" type of solution, but it does seem like it would increase quality of life as it is meant to. Similar to SSRIs.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#36
The article acts like ibogaine is a newly discovered drug. This is an old hallucinagenix drug that has helped thousands of people get over ptsd. The only thing holding this back is government bureaucracy and red tape. I’m happy that people will get there chance to benefit from this after decades of stupid government policy.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#37

This is, I am assuming from the context, not opporating under the assumption PTSD often is rooted in brain damage from exposure to shockwaves.

Would the treatment be any different? It's my understanding that were have no way of accelerating repair from neurological damage and instead focus on therapies to regain ability.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#38
post #8

Only veterans? I wonder about the editorial choice to use veterans rather than, say, women who have PTSD from assaults, which is a much larger group of people. (Approximately 4% of US men and 8% of US women experience PTSD every year across all reasons like accidents, sexual assaults, combat, etc.) Presumably this treatment would help everyone? Or is it somehow supporting only vets?

The research on ptsd began with US veterans afaik. It’s probably the group that is most studied for it and also receives trials.

The US also spends a large amount of money on each veteran. If they can find a cure for trauma they would benefit hugely from it. The side effect of this is that others would benefit as well.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#39
post #8

Only veterans? I wonder about the editorial choice to use veterans rather than, say, women who have PTSD from assaults, which is a much larger group of people. (Approximately 4% of US men and 8% of US women experience PTSD every year across all reasons like accidents, sexual assaults, combat, etc.) Presumably this treatment would help everyone? Or is it somehow supporting only vets?

Way back in something like 2002, I was in college. One day at my then-girlfriend’s apartment east of campus, she got a phone call. An old friend of hers was in town, so she told him to come over. I don’t know his name, but let’s call him J., which is a randomly selected letter.

J. was a traveling Ibogaine ... healer? He went from city to city, summoned by the loved ones of advanced heroin addicts, to attempt one last Hail Mary shot at recovery.

These were situations of absolute desperation, and I can’t overstate the seriousness with which he took his adopted occupation. He described to us in detail his process.

First, he interviewed the person requesting help, seeing what else they had tried and trying to suss out if Ibogaine would be worth the risk. He turned away most callers.

Those who he accepted would be dropped off at his van, inside which was a mobile, DIY ICU of sorts: a bed, food, water and emergency medical supplies. He would administer the ibogaine (I don’t know what form this took), and then, in his words, the patient would undergo a 2 to 3-day continuous hallucination.

During this time, in J.’s observations, the patient was almost always ‘visited’ by dead relatives, who typically admonished the patient for what had become of them, laying into them with real talk about the state of their life.

J. said half of the patients came out of this experience fundamentally changed, and effectively cured of their addiction to heroin. I don’t know if he had any data (anecdotal or otherwise) on recidivism, but the implication was that this was likely to be permanent.

But, he said, the other half went insane, which is why he spent a great deal of effort screening families and informing them of the risks.

I don’t know how much, if any, of this is true. I don’t know what ‘insane’ means, or meant. But I remember vividly how seriously this guy took it, without ever coming off as some kind of self-satisfied guru or medicine man, believing himself to be a god, or anything like that. He never accepted money. He lived somewhat roughly. I wonder whatever happened to that guy.

Re: Trials on veterans suggest ibogaine could provide a new treatment for PTSD

#40
post #6
post #3

It seems strange to me to choose ibogaine when Salvia divinorum seems like it has a similar psychological experience without the physical heart risk.

Saliva divinorum is inherently dysphoric due to its agonism of the kappa opiod receptor. For a different cheap legal drug that affects serotonin and the NMDA receptors like ibogaine does, there's always off label use of dextromethorphan (cough medicine)!

Again I'm a bit baffled as to what the unstated thought process is. Ibogain and Saliva divinorum share a short term dysphoric experience from kappa opioid receptor interference that might be an effective way to eliminate Trauma from earlier memories. Why use the more dangerous of the two and why avoid the experience if the experience is the intervention?
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