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Longevity Linked to Proteins That Calm Overexcited Neurons

quantamagazine.org

31–40 of 59 posts

Re: Longevity Linked to Proteins That Calm Overexcited Neurons

#32

Earlier quoted context omitted.

There’s a theory that longevity is lower in men because they need to be stronger in order to survive in a conflict. It’s a trade off. Physical strength is the result of growth, but some of the same pathways for increased growth are also theorized to be the root cause of aging. Note that this is independent of strength training; it’s the ability to get stronger, rather than actually getting stronger (among other relat…

The big killer among modern elderly people is the massive muscle wasting that accompanies most inpatient hospital procedures. Having a solid foundation of muscle can insulate a person from the dreaded point of no return after which it would be impossible to build one's body back after a procedure.

Even without being bedridden for days after an inpatient procedure, we have an epidemic of frailty among elderly people. This commonly causes serious falls and fractures, and after an incident like that most people fall into a rapid downward spiral. As a matter of public health policy we should be prescribing weight training and higher protein diets for elderly people.

Re: Longevity Linked to Proteins That Calm Overexcited Neurons

#34

> The results may help explain the observation that some drugs used for epilepsy extend life span in lab animals. It would be interesting to find out if CBD (seizure control, calming effect) might be beneficial in increasing levels of REST and calming neural activity.

that's was the first thing that I thought.. Together with Sex.

Re: Longevity Linked to Proteins That Calm Overexcited Neurons

#35

Earlier quoted context omitted.

Life expectancy was the same for both genders in 1900 (in Europe at least). We’ve just made continually more progress for women than for men. Nowadays for example: lots of research on female cancer (twice more funding than male cancers, for the same incidence and mortality) and domestic violence, little budgets on suicide. Lots of money for equality at work where women are fewer, little money for boys massively dropp…

You are driving a thesis here but using only data which supports that thesis. There are many other reasons why, at least in the culture I'm familiar with (the USA) men have tended to live shorter. These are all stated in past tense, though many are still true today: - men smoked at higher rates than women - men were more likely to drink heavily - men were more likely to engage in dangerous work (construction vs nursi…

Exploration vs exploitation at work. Teenage men are way more biased towards exploration, whether it's good or bad. Sometimes some of them figure out something great that improves civilization. Without that risk taking we all would be dead or in zombie mode.

Re: Longevity Linked to Proteins That Calm Overexcited Neurons

#37
post #2

Could this be related to the generally shorter lifespans of males?

Life expectancy was the same for both genders in 1900 (in Europe at least). We’ve just made continually more progress for women than for men. Nowadays for example: lots of research on female cancer (twice more funding than male cancers, for the same incidence and mortality) and domestic violence, little budgets on suicide. Lots of money for equality at work where women are fewer, little money for boys massively dropp…

Please don't take HN threads into gender flamewar. Last thing we need here.

https://news.ycombinator.com/newsguidelines.html

Re: Longevity Linked to Proteins That Calm Overexcited Neurons

#38
post #14

Does this relate in any way to the anti-aging drug cocktail that we saw a few months ago? IIRC that one related to genetic aging markers, and stress can affect mitosis. It seems like immortality has a lot of building blocks, and the research isn't far enough to combine them yet.

Anyone have a link to that? Sounds interesting.

Re: Longevity Linked to Proteins That Calm Overexcited Neurons

#39

Earlier quoted context omitted.

Life expectancy was the same for both genders in 1900 (in Europe at least). We’ve just made continually more progress for women than for men. Nowadays for example: lots of research on female cancer (twice more funding than male cancers, for the same incidence and mortality) and domestic violence, little budgets on suicide. Lots of money for equality at work where women are fewer, little money for boys massively dropp…

I know that your points are standard masculinist talking points and I most probably won’t change your perspective. As I understand it, you seem to point the blame for men relatively shorter lifespan (which in fact have consistently grow over the last decades in OCDE countries, except in the US) toward “more attention to women’s issues”. Of course every single bit of attention to women’s issues have been a very long h…

Raise men as girls? What good parent doesnt try and raise there sons do have care and empathy and to be reasonable? Are there any positive traits that you think men possess? You are only taking the negative side of mens tendency for risk taking. Willingness to take risks has many positive benefits like getting to the top management spots you mentioned.

Re: Longevity Linked to Proteins That Calm Overexcited Neurons

#40
post #14

Does this relate in any way to the anti-aging drug cocktail that we saw a few months ago? IIRC that one related to genetic aging markers, and stress can affect mitosis. It seems like immortality has a lot of building blocks, and the research isn't far enough to combine them yet.

Anyone have a link to that? Sounds interesting.

I’d like to read as well.
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