Longevity Linked to Proteins That Calm Overexcited Neurons
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Longevity Linked to Proteins That Calm Overexcited Neurons
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Re: Longevity Linked to Proteins That Calm Overexcited Neurons
#2Could this be related to the generally shorter lifespans of males?
Re: Longevity Linked to Proteins That Calm Overexcited Neurons
#3Could this be related to the generally shorter lifespans of males?
This ain’t it, chief
Re: Longevity Linked to Proteins That Calm Overexcited Neurons
#4Could this be related to the generally shorter lifespans of males?
Life expectancy was the same for both genders in 1900 (in Europe at least).
We’ve just made continually more progress for women than for men. Nowadays for example: lots of research on female cancer (twice more funding than male cancers, for the same incidence and mortality) and domestic violence, little budgets on suicide. Lots of money for equality at work where women are fewer, little money for boys massively dropping at school. Practically no help if you are a man facing a male-specific issue, which is why a lot of them engage in the army or in Daesh (depending which side they tilt towards), and practically all killers you know are boys victims of harassment, absent father syndrome and on the spectrum of autism, with no help from the social fabric.
Men live shorter not because it is nature, but because we’ve made less progress for them.
Re: Longevity Linked to Proteins That Calm Overexcited Neurons
#5Could this be related to the generally shorter lifespans of males?
Life expectancy was the same for both genders in 1900 (in Europe at least). We’ve just made continually more progress for women than for men. Nowadays for example: lots of research on female cancer (twice more funding than male cancers, for the same incidence and mortality) and domestic violence, little budgets on suicide. Lots of money for equality at work where women are fewer, little money for boys massively dropp…
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Re: Longevity Linked to Proteins That Calm Overexcited Neurons
#6> In their new study, Yankner and his colleagues report that the brains of long-lived humans have unusually low levels of proteins involved in excitation, at least in comparison with the brains of people who died much younger. This finding suggests that the exceptionally old people probably had less neural firing. To investigate this association in more detail, Yankner’s team turned to C. elegans. They compared neural activity in the splendidly long-lived daf-2 mutants with that of normal worms and saw that firing levels in the daf-2 animals were indeed very different.
> “They were almost silent. They had very low neural activity compared to normal worms,” Yankner said, noting that neural activity usually increases with age in worms. “This was very interesting, and sort of parallels the gene expression pattern we saw in the extremely old humans.”
Does the low neural activity correlate with a less active experience of the world? Are you experiencing your state with the mute button on? I'm no neurosurgeon, but if this is the trade-off, perhaps living longer by using this REST gene might result in a less rich, dynamic, and textured experience? Might it mean living a life like this is less 'fun'?
Re: Longevity Linked to Proteins That Calm Overexcited Neurons
#7> In their new study, Yankner and his colleagues report that the brains of long-lived humans have unusually low levels of proteins involved in excitation, at least in comparison with the brains of people who died much younger. This finding suggests that the exceptionally old people probably had less neural firing. To investigate this association in more detail, Yankner’s team turned to C. elegans. They compared neura…
Depends on the nature of activity. Pure stress will activate your brain but experience is mostly degraded.
Re: Longevity Linked to Proteins That Calm Overexcited Neurons
#8Could this be related to the generally shorter lifespans of males?
Life expectancy was the same for both genders in 1900 (in Europe at least). We’ve just made continually more progress for women than for men. Nowadays for example: lots of research on female cancer (twice more funding than male cancers, for the same incidence and mortality) and domestic violence, little budgets on suicide. Lots of money for equality at work where women are fewer, little money for boys massively dropp…
Do you have a citation for the formerly same life expectancy in men and women. I cannot find any.
Re: Longevity Linked to Proteins That Calm Overexcited Neurons
#9Earlier quoted context omitted.
Life expectancy was the same for both genders in 1900 (in Europe at least). We’ve just made continually more progress for women than for men. Nowadays for example: lots of research on female cancer (twice more funding than male cancers, for the same incidence and mortality) and domestic violence, little budgets on suicide. Lots of money for equality at work where women are fewer, little money for boys massively dropp…
Do you have a citation for the formerly same life expectancy in men and women. I cannot find any.
Historically women likely had to deal with high death in child birth rates.
Re: Longevity Linked to Proteins That Calm Overexcited Neurons
#10> The results may help explain the observation that some drugs used for epilepsy extend life span in lab animals.
It would be interesting to find out if CBD (seizure control, calming effect) might be beneficial in increasing levels of REST and calming neural activity.