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Vitamin D Insufficiency is Prevalent in Severe Covid-19

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Re: Vitamin D Insufficiency is Prevalent in Severe Covid-19

#251
post #186

Earlier quoted context omitted.

If you do get enough sun exposure without the protective clothing you'll probably damage the shit out of your skin.

Fortunatly, its fine. https://news.ycombinator.com/item?id=23024436

How much of the body must be exposed?

Re: Vitamin D Insufficiency is Prevalent in Severe Covid-19

#252

Earlier quoted context omitted.

the benefits of sunlight outweigh the risks. Avoid burning, but know that tanning is not correlated with melanoma (assuming you have skin that tans; otherwise, ignore this).

> tanning is not correlated with melanoma This conflicts with what I've always been taught, and with every high google result for 'tanning skin cancer'. (I'm in Australia, where the sun is especially damaging; but I'd be surprised if tanning were very dangerous here but fine elsewhere, and in any case the search results were not all local.) What are you basing it on?

It gets complicated. Sunburn (occasional high dose of sun) is unequivocally bad, and highly correlated with skin cancer. Regular, moderate exposure (could be described as tanning) is correlated to lower risk of cancer than getting little sun.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313493/

An examination of the current state of the scientific research shows that (i) severe sunburns are linked to increased risk of melanoma but non-burning sun exposure is linked to reduced risk of melanoma

Re: Vitamin D Insufficiency is Prevalent in Severe Covid-19

#253
post #185

Earlier quoted context omitted.

Interesting. The Zinc supplement that I started taking a couple times of week due to COVID-19 exceeds all upper limits listed on Wikipedia when taken at the recommended daily dose (50 mg). https://en.wikipedia.org/wiki/Zinc#Dietary_recommendations > In the case of zinc the adult UL is 40 mg/day (lower for children). > The EFSA reviewed the same safety question and set its UL at 25 mg/day, which is much lower than the…

Please be carefull with trace element as supplements, only take it if your doctor agree and don't self-medicate. When i was younger a kid in my school almost killed himself with iron poisoning (well, rather his parents almost killed him).

"Be careful" as "know which number is bigger than the other"

You're right, people should know that 50mg is bigger than 40mg/25mg (at least for a safe prolonged daily limit - single dosage limit might be higher https://en.wikipedia.org/wiki/Zinc_toxicity ). It's kindergarden level math and still it seems people have trouble with it.

I'm not being ironic, it seems that's a common problem. Maybe explains why the situation got to the point it got.

Re: Vitamin D Insufficiency is Prevalent in Severe Covid-19

#254
post #42

Earlier quoted context omitted.

Well yes, Vitamin D is pretty hard to come around in the northern hemisphere so no surprise there. Mind you, it's far not the only thing - magnesium, zinc, selenium are just a few which most people are missing. I mean unless your diet consists entirely of tuna and salmon probably. Over the last few years, I've stressed significantly on my physical health(after being very overweight for the most of my adult life and n…

what’s your stack look like? I’ve got D3, Zinc, and Magnesium. Occasionally a multivitamin, melatonin, or calcium (for arthritis)

I go for a bundle of these[1] every 2 or 3 days, depending on how often I train and in the days between D-3 (1000 IU), vitamin C+zinc (1000mg for C), magnesium citrate 200mg.

IMPORTANT NOTE: I do train a lot and I'm in the 6-8% body fat range so generally I have higher needs. The ones in the link are bundled up in small bags of 11 pills and the values are for 2 packs of 11 which is a complete overkill if you are not a top tier athlete. 1 pack of 11 every 2 or 3 days is sufficient for regular people.

[1] https://cdn.shopify.com/s/files/1/0944/0726/files/Universal-...

Re: Vitamin D Insufficiency is Prevalent in Severe Covid-19

#255
post #191

Earlier quoted context omitted.

Damaging high doses can be as little as a few minutes in the Australian summer so I think it's fair to keep that in mind. On your evolution comment, most Australians don't have dark skin, but the ones who were here before Europeans do. I think that is a good indicator that the body is adjusting to something harmful. On the other hand, many dark skinned people in Britain aren't in a climate they evolved for either. We…

Adding some information for those interested in more precise numbers. This paper [1] has the recommended exposure time for a few cities in Australia. If you live in the same latitude, as long you live in the same latitude, this can be used as a guideline. https://staging.mja.com.au/system/files/issues/194_07_040411...

I haven't kept up with the Ozone Hole lately, but I believe it's not uniformly distributed so keep that in mind too if it's still a problem. I'm pretty sure it was usually more of a problem in Australia than South America for example.

I couldn't believe it the first time I went to Singapore, in 35C heat all day in the sun at a theme park, and didn't even get a minor blush on my pale skin due to the humidity and latitude. Definitely eye opening coming from NSW, Australia.

Re: Vitamin D Insufficiency is Prevalent in Severe Covid-19

#256
post #42

Earlier quoted context omitted.

Well yes, Vitamin D is pretty hard to come around in the northern hemisphere so no surprise there. Mind you, it's far not the only thing - magnesium, zinc, selenium are just a few which most people are missing. I mean unless your diet consists entirely of tuna and salmon probably. Over the last few years, I've stressed significantly on my physical health(after being very overweight for the most of my adult life and n…

What is the one in particular?

See my other reply.

Re: Vitamin D Insufficiency is Prevalent in Severe Covid-19

#257

Earlier quoted context omitted.

Nobody makes any money if it turns out to be a good treatment, so nobody will fund the research

This is actually very true. There are lots of potential treatments that use generic and non-patentable agents, and very few people are willing to look into it. Zinc is the classic example; some people think it maybe reduces the duration of the common cold. The common cold is one of the main causes of missed workdays. If there's a drug that could make you miss 4 days of work a year instead of 5 days of work a year, it…

Isn't the US government funding a lot of the medicine/health studies?

Re: Vitamin D Insufficiency is Prevalent in Severe Covid-19

#258
Most of us are Vitamin D deficient. We do not spend enough time in direct sunlight for an hour with all our limbs exposed.

I've been taking 5000 IU for last 10 years to maintain ~55 ng/mL after finding out I was dangerously low at 12 ng/mL. And I used to live in Australia, the land of constant sunshine.

I avoid listening to the FDA recommended dose which has historically been increasing every few years. Just get your blood work done and supplement to maintain around ~ 55 ng/mL. That's better than listening to generic advice.

Btw. This pissed me off when BlueShield few years ago stopped covering Vitamin D blood tests because of this nonsense:

Most People Don't Need Vitamin D Testing https://www.bcbs.com/news/press-releases/most-people-dont-ne...

"The U.S. Preventive Services Task Force recently found the current medical evidence insufficient to assess the balance of benefits and harms of screening for vitamin D deficiency in asymptomatic adults."

"The American Society of Clinical Pathology contributed the following recommendation to Choosing Wisely®, “Many people have low levels of vitamin D, but few have seriously low levels. Most of us don’t need a vitamin D test. We just need to make simple changes so we get enough vitamin D.”"

Re: Vitamin D Insufficiency is Prevalent in Severe Covid-19

#259
Question for those more knowledgeable: From the abstract it doesn't seem like they compared this group with other people in the ICU - could the lack of sun exposure for that population play a role? ICU patients with COVID-19 have likely gone from sheltering in place at home to experiencing symptoms that make them unlikely to venture outside to the hospital where they can't leave, all of which means less exposure to the sun. Is a few weeks of staying indoors enough to cause this?

Re: Vitamin D Insufficiency is Prevalent in Severe Covid-19

#260
post #43

Earlier quoted context omitted.

You’ve got the causality the wrong way round

Yeah, and Italy, Spain, and France are some of the sunnier countries in Europe (compared to Germany, UK, Belgium, Scandinavia, etc). If anything I would expect vitamin D deficiency to be less common there.

Don't forget Ecuador which is literally on the equator and experiencing a major outbreak.
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