There's a big difference between "using Tylenol may increase the risk of autism" and "Tylenol causes autism".
If this study is accurate, it merely links the two together, and does not provide the reason. The problem with RFK is he's using it as a way to appease his own base to justify an anti-vaccination and anti-science agenda.
Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
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Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
#242Earlier quoted context omitted.
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Sure it can. Type 2 diabetes is both hereditary and lifestyle/behavioral influenced . Same with cancer, if you have cancer in your family your risk of getting cancer is higher. I would say most medical issues are both. Heart disease, gout, obesity, hypertension,strokes,asthma etc.
Let me put this a bit differently: Type 2 diabetes is both genetic and can be acquired during one's life (e.g. through bad dietary choices). But a man who develops diabetes does not acquire genetic T2D by doing so - he cannot pass it on directly to his children.
Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
#243It’s insane that the RFK crowd continues to not consider that the increase is just due to better diagnoses. I wouldn’t entirely rule out there being environmental factors, but from the data I could gather it seems that acetaminophen usage has decreased in pregnancy over the last several decades in the US, while autism has increased. This all seems to go back to the boomer generation believing the world was simpler wh…
Better diagnosis and that autism covers a wider range of symptoms.
Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
#244Here's the relevant study from earlier this year: https://hsph.harvard.edu/news/using-acetaminophen-during-pre... It's a meta-analysis that considered a bunch of individual studies, their effect size, and their quality. It claims that Tylenol use has increased alongside a 20-fold increase in autism rates, suggesting causation, and recommends immediate efforts to reduce Tylenol use during pregnancy. One objection that…
I'm extremely suspicious of anything that looks at 'an increase in autism rates' without considering the same factors that have gone into there being 'more' left-handed people over the past 50 years or so. There are a lot of people in the past who 'weren't left handed' because they were punished as children if they showed left-handed behavior, and that's still a whole lot less stigmatized than autism.
Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
#245Here's the relevant study from earlier this year: https://hsph.harvard.edu/news/using-acetaminophen-during-pre... It's a meta-analysis that considered a bunch of individual studies, their effect size, and their quality. It claims that Tylenol use has increased alongside a 20-fold increase in autism rates, suggesting causation, and recommends immediate efforts to reduce Tylenol use during pregnancy. One objection that…
> If you think about it though, someone knowledgeable enough to write this paper is exactly the kind of person you'd want to serve as an expert witness.
Maybe, but the same was also true of the now disgraced Andrew Wakefield, although his conflict of interest was even greater since he didn't reveal his funding before publishing his original paper.
Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
#246Here's the relevant study from earlier this year: https://hsph.harvard.edu/news/using-acetaminophen-during-pre... It's a meta-analysis that considered a bunch of individual studies, their effect size, and their quality. It claims that Tylenol use has increased alongside a 20-fold increase in autism rates, suggesting causation, and recommends immediate efforts to reduce Tylenol use during pregnancy. One objection that…
Has the study stratified for improved diagnosis? When I was a child in the 80's teachers weren't looking for the telltale signs, but you better believe there were autistic poeople, they just weren't diagnosed.
Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
#247I'm always surprised at the hostility to Acetaminophen on HN (or Paracetamol as we call it here in the UK). It's one of the most commonly used medicines in the UK - and certainly the most popular painkiller. YouGov even did a survey confirming that - https://ygo-assets-websites-editorial-emea.yougov.net/docume... The safety aspects of it are not something that gets raised in the UK much - other than suicide attempts,…
It's weird that you're surprised, it's one of the most dangerous otc drugs, and is the leading cause of liver failure on the planet. I'm always surprised that British people treat it like aspirin, because an overdose can easily kill you.
I'm serious. Over 50% of all liver failure is due to acetaminophen, and 20% of liver transplants.
Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
#248Buy the dip?
Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
#249Earlier quoted context omitted.
If Paracetamol was invented today it would likely never receive an OTC (over the counter sale, meaning you can just buy it from a retail outlet the way you'd buy cough medicine or toothpaste) license in the UK. Yes, it's safe (and for a bunch of people including me, effective) at the licensed dose, but it's useless at about half that dose, and it's toxic, leading to very nasty deaths in some cases, at just about 3-4…
Always surprises me as an American in the UK how hostile the UK is to paracetamol. You buy it in like 300-pill packages in the US, and I've literally never heard of anyone having a single accidental over-dose. I'm not sure I've ever heard of anyone intentionally overdosing on it, but I guess I can't rule that out since I'm aware of who 1-2 people personally have taken "a handful of pills". The efficacy window of driv…
The problem becomes, 8 tablets a day, minimum of 4 hours between doses is fine for a week or so, but do that for months and the liver toxicity creeps up on you.
Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
#250Earlier quoted context omitted.
We are not talking about medicines, we are talking about some that is frequently ingested/exposed to people. Things like plastics, additives, pesticides, EM signal. These are novel chemicals/radiation and are potentially slow toxins and showing a causal link from population studies is near impossible.
....nnno? We are primarily talking about Tylenol. Paracetamol. Acetaminophen. Perhaps you need to be reminded of the whole sentence you quoted from my post, rather than just the first subclause? > Until there are reputable studies that can actually show something resembling a causal link, getting angry at the medical community, pharmaceutical manufacturers, or vaccine makes for saying they are not responsible is poin…
We don't even know that autism is something that's caused. When sampling an integer, there's some probability you'll get a prime; perhaps when making a human, there's just some inherent probability you'll get an autistic person. (Afaik, we don't even know enough to put a likelihood on this class of theories.)