Earlier quoted context omitted.
It can , but that seems to be more related to poor implementations by the game devs, and not inherent to it. There are plenty of examples of games with Denuvo that still run fine (give or take your opinion on whether the presence of DRM is inherently "impacted performance").
If many of your users misuse your tool, that's a design problem not user error
I haven't seen their documentation, maybe the problem lies there. But there's no tool or documentation so perfect that nobody can use it wrong.