I'm glad people are realizing that all this social distancing is merely a pause button on the virus. Once we press play on society, exponential growth will happen again and we will have effectively rolled back the clock until we reach herd immunity through things like the OP's suggestion. At least this next time we'll hopefully have more PPE.
I'd much rather live in a world where everyone is required to wear masks all the time than live in a world where we are all told to stay home all the time. I believe it's also well established that any measures taken to slow the spread of a new virus will always result in fewer total deaths, in that sense quarantining is much more effective than just being a pause button.
A (possible) solution to Covid-19
231–240 of 585 posts
Re: A (possible) solution to Covid-19
#232Earlier quoted context omitted.
Technically they don’t provided we can get the herd immunity up to a decent level in the rest of the population. While it would be a good idea if the mutated strain was no more dangerous than a common cold coronavirus, we could drive the dangerous strains to extinction without having to infect the vulnerable.
Very difficult to get herd immunity up to a decent enough level without putting the vulnerable portion of the population in great danger though. Most countries are approaching something like 0.1% or 0.2% of the population having been infected. Herd immunity requires 70% - 80% immunity. About 350x - 800x more than what's happened already. Also the whole thing presumes that immunity is lasting. Some of the data is show…
Of course the other factor is who is a vulnerable person is a factor of the pathogenicity of the viral strain.
Re: A (possible) solution to Covid-19
#233Earlier quoted context omitted.
The whole idea of herd immunity in this context is fucking nonsense . No self-respecting epidemiologist would even bring it up this early into a pandemic. Herd immunity is the last resort for the immunocompromised or unvaccinated, not the foundation for public health policy.
Not sure who says it's last resort. There's a paper linked in a sibling comment about herd immunity's role in smallpox eradication.
Re: A (possible) solution to Covid-19
#234Earlier quoted context omitted.
(I am not a professional, so what I write below might be wrong) Having more time to develop a vaccine or effective treatments is essential, it doesn't have to be herd immunity. Plus in countries where covid19 rate is low enough, social distancing can be helpful for finding and isolating clusters to suppress the epidemic.
Of course, there are two ways out of this, herd or vaccine. The above is a variation of herd that may result in less deaths. The real problem is that waiting until a vaccine is just not even remotely realistic for so many reasons that it's not even funny. We could end up causing more indirect deaths with social isolation than we could possibly imagine, worst case being a huge collapse in the economy results in a larg…
Re: A (possible) solution to Covid-19
#235You noted on your post "live attenuated (oral) polio vaccine" but later wrote "Apart from the time it will take to develop, trial, and mass produce a vaccine (12-18 months), it is unlikely that any vaccine will be practicable."
So how do you imagine this solution being administered if not as a vaccine? Is the solution a Pox Party (https://en.wikipedia.org/wiki/Pox_party) with someone verified to have the harmless strain?
Re: A (possible) solution to Covid-19
#236I'm glad people are realizing that all this social distancing is merely a pause button on the virus. Once we press play on society, exponential growth will happen again and we will have effectively rolled back the clock until we reach herd immunity through things like the OP's suggestion. At least this next time we'll hopefully have more PPE.
I'd much rather live in a world where everyone is required to wear masks all the time than live in a world where we are all told to stay home all the time. I believe it's also well established that any measures taken to slow the spread of a new virus will always result in fewer total deaths, in that sense quarantining is much more effective than just being a pause button.
Re: A (possible) solution to Covid-19
#237Earlier quoted context omitted.
We are talking infection fatality rate not infection rate. Infection fatality rate is number of people who die after they are infected. That's one of the most important numbers and it can be estimated. It's different from case fatality rate. Number of people diagnosed with COVID-19 who die. You started your argument trying to argue based on your understanding of what the infection fatality rate is.
Nobody knows the true infection fatality rate. Probably the best estimate we can make is from South Korea where they have done a pretty good job of testing everyone infected. There the infection fatality rate is 1.8% and rising as the cases age out and people in the ICUs die.
It can be estimated with increasing accuracy.
> There the infection fatality rate is 1.8% and rising as the cases age out and people in the ICUs die.
You continue citing case fatality rate (CFR) numbers and call them infection fatality rate numbers (IFR). Can you please go back to your sources and read what they say. I bet they are case fatality rates. In South Korea one IFR estimates put the number around 0.4 and 0.7%.
Here are some IFR estimates:
1. Estimating the infection fatality rate of COVID 19 in South Korea by using time series correlations https://figshare.com/articles/Estimating_the_infection_fatal...
2. Estimating the infection and case fatality ratio for coronavirus disease (COVID-19) using age-adjusted data from the outbreak on the Diamond Princess cruise ship, February 2020 https://www.eurosurveillance.org/content/10.2807/1560-7917.E...
3. Using early data to estimate the actual infection fatality ratio from COVID-19 in France https://www.medrxiv.org/content/10.1101/2020.03.22.20040915v...
4. Robust Estimation of Infection Fatality Rates during the Early Phase of a Pandemic https://www.medrxiv.org/content/10.1101/2020.04.08.20057729v...
Re: A (possible) solution to Covid-19
#238Earlier quoted context omitted.
The OP literally opens with a misinterpreted statistic. It links to an article about CFR and claims that the values are IFR instead of CFR. This is not "getting caught up on something", I'm pointing out a fundamental error. Most serious estimates of IFR are between 0.1 and 0.6%. The OP should be edited to either correctly state that COVID-19 kills between 1 and 3.5% of identified cases , or be updated to use numbers…
These IFR numbers you quote are also incorrect as there are many people infected who have not yet had time to die. The best estimate probably comes from South Korea (they seem to be picking up nearly all cases with their massive contact tracking and testing) where the death rate is at 1.8% and trending higher.
Re: A (possible) solution to Covid-19
#239How does the Iceland data suggest the hypotheses that 1) an attenuated strain exists in the wild and 2) it provides immunity to the worse strain? It's asserted in the post, but I don't see it. It seems likely to me their experience isn't any different from any other country's, and they're just testing more. The idea in the post is obviously a good one if it can be done, it's just that it seems like a generic idea tha…
As for why people aren’t working on this idea I don’t know. Maybe someone is and they will send me an email and I can update my post. I would certainly be extremely happy with this outcome.
Re: A (possible) solution to Covid-19
#240Earlier quoted context omitted.
Or until something like 95% of population has been infected and we know for sure that those who already had the disease can not spread it anymore.
What about people born after that point? As immune people die over time from other causes, and as people are born without immunity, the percent of the population with immunity from having had it falls. Non-vaccine acquired herd immunity is temporary.