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#231

Earlier quoted context omitted.

Post a link because I right now I have no reason to believe you.

I posted links to one of the in vitro studies here, and in the comments I posted the press release for the FDA approval: https://www.reddit.com/r/covid19stack

Your information is wrong and misleading. It’s irresponsible for you to post stuff like this.

Re: undefined

#232
post #44

Earlier quoted context omitted.

It's been tested for years (decades? it's generic) as an anti-malaria drug. Any drug can be overdosed.

It hasn’t been tested against Covid-19. Recommending (or even vaguely hinting) that people just try random drugs that the FDA has approved for other uses is not a strategy with no downside.

There's two reasons to test drugs. (1) To know it's effective. (2) To know it's (reasonably) safe. Chloroquine has passed (2), which is relevant for this article.

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#233

Earlier quoted context omitted.

You're surely aware that Trump regularly declares himself more knowledgeable than the experts and derides his critics as 'fake news' or 'never trumpers' etc. etc. It's not a stretch to think that more credulous folk might take his tweets literally in defiance of common sense, given the media ecosystem dedicated to promoting his 24-7.

Trump didn’t come up with or popularize the idea for this treatment. All he’s done is instruct the FDA to trial it, and stated exactly when a doctor can prescribe it. This is nothing more than any of the other doctors or health officials who think the treatment has potential have done. There is no possible way that any of his comments could be construed as advice to illegally acquire and self-medicate with a drug you…

Now now, there are multiple quotations on this thread showing that not to be true.

Re: undefined

#234
post #208

Earlier quoted context omitted.

There are plenty of drugs with a narrow therapeutic index (NTIs or NTIDs), some of which are available over the counter. Some extremely popular ones: lithium, valproic acid, acetaminophen, almost all anticoagulants (warfarin/heparin), almost all of the -mycin antibiotics (and a lot of other antibiotics), all of the tricylic antidepressants. See this paper for a very interesting discussion of the topic: https://www.nc…

People taking warfarin literally have serum levels measured frequently. Typically lithium and valproate too. TCAs barely used any longer. Acetaminophen doesn’t belong in this conversation with the other drugs.

Acetaminophen doesn’t belong in this conversation with the other drugs.

I don't see why not? It's a good example where the max therapeutic dose (4000mg/day) is within 2X of the toxic dose range (7500mg-10000mg/day). And even the max therapeutic dose can be toxic to the liver.

And it's exceptionally easy to accidentally overdose if you don't read product labels, since you could be taking multiple products that contain it.

Re: undefined

#235

Earlier quoted context omitted.

And do you think that is what every other person is reading?

Clearly not, judging by how my votes are doing. But I think their emotions are getting in the way, leading them to see things that aren't there.

Wait, sorry I think I misread you. Do I think every other person is reading that the president is asking people to take things without doctor's orders? Sort of, perhaps I'm being unfair. However, it seems rather directly to be the interpretation of the person who posted it, because they are replying to a request for an example of the president recommending "that the public obtain and self medicate with chloroquine".

Re: undefined

#236
post #2

The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.

They didn't take the drug, they took an aquarium cleaner... http://bannerhealth.mediaroom.com/chloroquinephosphate >A man has died and his wife is under critical care after the couple, both in their 60s, ingested chloroquine phosphate, an additive commonly used at aquariums to clean fish tanks. Within thirty minutes of ingestion, the couple experienced immediate effects requiring admittance to a nearby Banner Health…

[deleted]

Re: undefined

#237

Earlier quoted context omitted.

And do you think that is what every other person is reading?

Clearly not, judging by how my votes are doing. But I think their emotions are getting in the way, leading them to see things that aren't there.

I'm not sure how it is across all of the US, but when I was in NY, I was certainly surprised to see advertisements for prescription drugs on TV. These always embed "ask your doctor about X".

That's just completely unheard of in Australia. You cannot advertise prescription drugs to consumers, period.

Maybe Americans are just more likely to self-diagnose and self-medicate in general? Or visit the doctor with an agenda for a drug, and see the doctor's prescription as mere paperwork?

Re: undefined

#238
post #44

Earlier quoted context omitted.

It's been tested for years (decades? it's generic) as an anti-malaria drug. Any drug can be overdosed.

That's an oversimplification. The amount for an overdose is only around 3X a regular dose (2g vs 600mg) In contrast, most drugs for which you overdose need to be at much higher dosage multiples compared to the prescribed dose.

I'm fairly libertarian so I'm going to say, that's fine. As long as the correct / max dosage is noted on the label/instruction sheet (don't know about US, but in Slovenia, pretty much every drug, even common ones like Aspirin, come with detailed instructions), I don't really see the need to excuse people from being responsible adults (with possible exception for opioids and other addiction-prone drugs).

Re: undefined

#239

Earlier quoted context omitted.

President talks about the preliminary reports that HCQ is working for treating COVID-19 around the world. It might be a good treatment here. People freak out. "Preliminary doesn't mean proven!" Man self-medicates with HCQ and dies. President's fault??

President shouldn't talk about things he clearly doesn't understand. Compare this to how Obama used to measure every single word he said.

All presidents talk about stuff they don't understand.

Re: undefined

#240
post #2

The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.

I am an extremely pro-self-medication (implying every literate person should have basic medical education knowing how does their body function and how to maintain it optimally) and anti-scheduling person yet hell yeah I agree - people whom many people believe in, especially the officials like the freakin president should quadruple-check before saying anything what can be risky. Billions of people listen to him, a huge portion of them is not particularly bright, he should take that in account. Ideally it should be illegal for an official to say anything that is not scientifically correct.
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