Earlier quoted context omitted.
It really isn't. Unless you have a card without a driver (exceedingly rare, though it's not uncommon to need a recent kernel to use recent hardware) ALSA pretty much Just Works. For complex features like streaming sound over the network you need PulseAudio, which due to its complexity takes more configuration and setup, but that's done out of the box on a fair number of distros. I don't know of any major software tha…
PulseAudio still gives me pain. There's an intel-hda driver issue https://bbs.archlinux.org/viewtopic.php?pid=920549 that has a workaround, but the workaround only f's up other programs for me.
My condolences. I also have that one and solved the problem by shoving a cheap second hand Creative SB Audigy in the PCI slot. And It still crackles and pops and messes up every time skype makes a sound.
Edit: to clarify, using a PCI soundcard solved the crackling and popping in every application except skype, which I find acceptable for now, since I don't usually talk on skype. I might experiment with using JACK and somehow routing pulse through that.