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Scientists may have found mechanism behind cognitive decline in aging

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Re: Scientists may have found mechanism behind cognitive decline in aging

#211

Post by throw__away7391 »

acters wrote: post #205
throw__away7391 wrote: post #174

Earlier quoted context omitted.

No it doesn't. I'm a good bit younger than 200 and barely remember large portions of my earlier life already. What's so special about 200 that makes it any different?

In another comment I spoke about how many more people are able to reach 60+ years of age, and that the amount of people living longer have exponentially grown. Our world population reaching another billions milestone at faster timeframes. Scarily, life expectancy was always at around 20-30 years for a large portion of history for humans.(most who reached 15 years of age were capable of living to 50 years albeit they…

So by your logic we should be trying to reduce human life expectancy?!

But honestly I really don't think these arguments are motivated by/a consequence of real belief in them, it's more a kind of cope with the current situation that we've become acclimated to, something in the vein of "if god intended men to fly they'd have wings".

Re: Scientists may have found mechanism behind cognitive decline in aging

#212

Post by thisguyfox »

koheripbal wrote: post #180
herval wrote: post #136

Earlier quoted context omitted.

I had the same after COVID. Took me many months to start feeling functional again. Any time I tried to think about something, it'd just... noise out? First 2-3 months were just awful I went to a neurologist who said there's tons of people coming in with the same complaint after COVID, and since there's no literature on that yet, he couldn't really do anything. It gets better.

I wonder how many people just fell into alcohol, isolation induced depression, sedentary lifestyle, weight gain, etc... and that their health decline had nothing to do with COVID. That's the issue with these anecdotes

When the pandemic hit I went the opposite. Focused on a healthy mind and body, was able to study a bunch and finally broken through a few mental plateaus.

But then I _got_ COVID and I can tell you COVID brain is real. Even after I had recovered physically there were a few weeks of obvious cognitive degradation. One of my first days testing negative I was trying to implement some pretty basic pagination logic but when it came time to writing the algos for it, it was like my body flipped a switch and I would get impossibly drowsy and have to go lie down.

I've had covid twice since then without the same problem but it is very real and wild.

Re: Scientists may have found mechanism behind cognitive decline in aging

#213

Post by dazc »

bluepod4 wrote: post #169
dazc wrote: post #150

Earlier quoted context omitted.

As it was explained to me, flouride will work in repairing microscopic areas of decay so long as the surfaces of your teeth are ultra clean. My dentist insists that I see the hygienist every 3 months for descaling, cleaning and basic checks. For the cynics, the cost of this is negligible and I have not needed a filling or any other costly procedure for over a decade.

Ohhh, I misinterpreted your comment. I think other people did too. It seemed as if you were saying that your dentist told you not to step foot in the dentist office at all for 18 months. But you just meant, the literal dentist doesn’t need to see you. Got it. I feel like this isn’t out of the ordinary now. I always hear every 6 months for a cleaning. This new “3-month” information takes a bit away from your original…

'Leading back to my original joke, maybe your dentist insisting that you need to get your teeth cleaned every 3 months is how they make their money lol!'

They make their money from implants and advanced treatments costing multiple thousands, not the £100 hygienist fees.

A hygenist, plus a nurse, seeing a maximum of 8 patients a day at £100 a time isn't a business I would want to be investing in.

Re: Scientists may have found mechanism behind cognitive decline in aging

#214

Post by mdp2021 »

scrollaway wrote: post #170
malauxyeux wrote: post #137

Earlier quoted context omitted.

> We can all prompt ChatGPT. I'm largely blind to this. If they're not wordy and overly polite, pasted ChatGPT answers just don't appear on my radar. Can someone help me out? What points to this answer in particular being from ChatGPT?

Some tell-tale signs (I work with GPT a lot as I mentioned in a sibling comment): - It's a list, it's numbered, it's got pretty consistent markdown formatting. This is especially present with ChatGPT - Title Casing In Each List Item - Strong usage of the passive voice - Strong CYA tone. "might promote", "studies suggest", "has been associated", "can convert", "possibly lowering", "thought to increase" The general str…

Sure, but hints are not proof. In fact,

> Would people actually[] write like this?

: some people do. What you call «CYA tone» can overlap with what for others is "precision".

It is the quality of the text, then, that hints further to actual intelligence or "artificial struggle".

Re: Scientists may have found mechanism behind cognitive decline in aging

#215

Post by datavirtue »

swalsh wrote: post #16

I've noticed a cognitive decline in myself the past couple years. I'm in my mid 30's though so I assume it's more related to long covid. One of the biggest side effects of long covid for me was horrible insomnia, which was killer. The insomnia is mostly gone, but I'm still not my previous cognitive self. It's terrifying to be honest.

I think a lot of problems are related to people thinking their sleep is good when it is not.

Re: Scientists may have found mechanism behind cognitive decline in aging

#216

Post by CodeSgt »

morelisp wrote: post #203
CodeSgt wrote: post #201

Earlier quoted context omitted.

“Exercise is healthy” is very, very far from “Bro science”.

"Exercise helps post-COVID cognitive decline and insomnia" is absolutely bro science, and especially since it can make the whole situation much, much worse.

That was never the claim. The claim was that it helps with brain fog and mental clarity in general, not specifically that caused by long-COVID, which had been proven to be true.

And a cursory look at the literature for PEM[1] will show you that the recommended path to recovery isn’t “avoid physical exertion at all costs”, but to do what you’re capable of and slowly ramp up the intensity, in which case small amounts of exercise could play a vital role.

[1] http://www.phsa.ca/health-info-site/Documents/post_covid-19_...

Re: Scientists may have found mechanism behind cognitive decline in aging

#217

Post by naasking »

koheripbal wrote: post #175
smallerdemon wrote: post #155

Fingers crossed that it can actually be replicated in future studies and research. We definitely don't want another nearly 20 years of false path ass busting research based on falsified documentation like we ended up with on Alzheimer studies.

I thought the fraud did not invalidate the results and that plaque was still considered the primary cause. In fact, wasn't there a drug recently released that demonstrated that?

> that plaque was still considered the primary cause.

Plaque has never been proven to be the primary cause of decline, it's just associated with it.

Re: Scientists may have found mechanism behind cognitive decline in aging

#218

Post by Teever »

smallerdemon wrote: post #155

Fingers crossed that it can actually be replicated in future studies and research. We definitely don't want another nearly 20 years of false path ass busting research based on falsified documentation like we ended up with on Alzheimer studies.

Is that actually what happened with Alzheimer research?

Re: Scientists may have found mechanism behind cognitive decline in aging

#219

Post by Teever »

koheripbal wrote: post #180
herval wrote: post #136

Earlier quoted context omitted.

I had the same after COVID. Took me many months to start feeling functional again. Any time I tried to think about something, it'd just... noise out? First 2-3 months were just awful I went to a neurologist who said there's tons of people coming in with the same complaint after COVID, and since there's no literature on that yet, he couldn't really do anything. It gets better.

I wonder how many people just fell into alcohol, isolation induced depression, sedentary lifestyle, weight gain, etc... and that their health decline had nothing to do with COVID. That's the issue with these anecdotes

Long COVID is real.

Re: Scientists may have found mechanism behind cognitive decline in aging

#220

Post by LoganDark »

DANmode wrote: post #194
LoganDark wrote: post #51

Earlier quoted context omitted.

I wonder if one could even guarantee a quick and early death without suicide. I assume if you join the military or something, if you get shot on the battlefield you could end up surviving with extreme pain, or bleeding out over a long period of time, neither of which are particularly desirable. There are various ways to go to sleep and never wake up, but I'd assume anything you did intentionally would be suicide. Som…

Exotic extreme sports, to answer your question. But, most people I've come across that are outward with this attitude say they smoke tobacco to help, and have a suicide method all planned out and ready to go as a guarantee.

> Exotic extreme sports, to answer your question.

Ah, so that's where the saying "do you have a death wish?!" came from :)

> But, most people I've come across that are outward with this attitude say they smoke tobacco to help, and have a suicide method all planned out and ready to go as a guarantee.

Having a plan and having the guts to carry it out are two different things. I've attempted suicide twice but chickened out both times. Honestly glad I didn't go through with it.

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