201–210 of 406 posts
Small study, probably not preregistered (didn't find anything about it in the description). Likely Publication Bias or p-hacking. I'm starting to get interested when it's been independently replicated.
Earlier quoted context omitted.
I am a neurologist. this is actually the exact opposite of what you should care about, which is "does it work to treat ___" In this trial, and 99% of other trials, there is no mechanism provided by the study, only a measurement of causality (which is the same thing as effectiveness). The authors may think they know based on other, prior, basic science research (as they are postulating here), but it does not affect th…
Obviously you don't understand HN.. everyone here is a "very smart software engineer" and knows far better than a simpleton like you with your decades of medical training and experience.
>Because curcumin's anti-inflammatory properties may protect the brain from neurodegeneration My very first question was: Please provide a possible physiological pathway for this. I'm so glad it was answered in the very first sentence. So many of these "Superfood does X" studies are just trials with 10 people over a month, with no explanation as to __how__ it could possibly happen. It significantly increases the skep…
I have done several experiments where I stopped taking it. Every time my joints got worse and then better after resuming cooking with Turmeric.
No idea how it works but it seems to work.
Earlier quoted context omitted.
I am a neurologist. this is actually the exact opposite of what you should care about, which is "does it work to treat ___" In this trial, and 99% of other trials, there is no mechanism provided by the study, only a measurement of causality (which is the same thing as effectiveness). The authors may think they know based on other, prior, basic science research (as they are postulating here), but it does not affect th…
Obviously you don't understand HN.. everyone here is a "very smart software engineer" and knows far better than a simpleton like you with your decades of medical training and experience.
http://slatestarcodex.com/2013/12/17/statistical-literacy-am...
Ask your local doctor next time you visit to tell you what a P value means.
The medical literature is a tragicomedy of statistical incompetence and malpractice.
Specifically on this study it has a lot of red flags: not pre-registered so p hacking can be assumed, industry sponsored which studies show greatly skews results, small numbers, unrealistically high effect sizes.
Earlier quoted context omitted.
I am a neurologist. this is actually the exact opposite of what you should care about, which is "does it work to treat ___" In this trial, and 99% of other trials, there is no mechanism provided by the study, only a measurement of causality (which is the same thing as effectiveness). The authors may think they know based on other, prior, basic science research (as they are postulating here), but it does not affect th…
The problem with “is this true?” Investigations is that there are tons of potential pitfalls and a combination of experimental limitations, poor academic incentives, and insufficient statistical and scientific training make this very hard to do well. I think it’s bad science, that will one day retrospectively be viewed as invalid scientific method. I think the way to combat this is to avoid studies that solely attemp…
A mechanism is really just a narrower example without irrelevant distractions or confounding variables.
Kind of like the difference between the bug reports: "run this complex workload on this specific machine and it will orobably crash after a few hours" versus "run these three commands when the cache is cold and it crashes".
>Because curcumin's anti-inflammatory properties may protect the brain from neurodegeneration My very first question was: Please provide a possible physiological pathway for this. I'm so glad it was answered in the very first sentence. So many of these "Superfood does X" studies are just trials with 10 people over a month, with no explanation as to __how__ it could possibly happen. It significantly increases the skep…
HN and QuantifiedSelfers find this as a niche site to record correlations and habits for self improvement.
https://betterself.io/ (Open sourced)
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Instead of taking tablets, try adding as an ingredient into your daily food. I think that will make it much easier to eat. Try cooking any Indian curries and turmeric is 90% of time default spice.
Curry is delicious, but it'd get pretty boring to eat it EVERY day.
We now have something called Traditional Knowledge Digital Library (TKDL) - http://www.tkdl.res.in/tkdl/langdefault/common/Home.asp?GL=E...
http://www.mondaq.com/india/x/586384/Patent/Traditional+Know...
Earlier quoted context omitted.
I am a neurologist. this is actually the exact opposite of what you should care about, which is "does it work to treat ___" In this trial, and 99% of other trials, there is no mechanism provided by the study, only a measurement of causality (which is the same thing as effectiveness). The authors may think they know based on other, prior, basic science research (as they are postulating here), but it does not affect th…
Obviously you don't understand HN.. everyone here is a "very smart software engineer" and knows far better than a simpleton like you with your decades of medical training and experience.
Others may value the mechanism more for very legitimate reasons. For instance, if you underatand the mechanism it leads to further research that could utilize a related mechanism or perhaps see potential side effects that would otherwise be hard to identify.
You really need both. "Is it true?" is a great starting place and oofers some treatments, but discovering the mechanism gives potentially a whole new class of treatments.