191–200 of 304 posts
I thought his discussion about it was interesting. Clearly there was other stuff going on, but he apparently felt his cannabis use was enough of a contributing factor that he decided to stop. https://www.youtube.com/watch?v=JBvc7Ny4iUk
Earlier quoted context omitted.
My understanding is that schizophernia is a predisposed condition. Cannabis can trigger it but not really cause it. (That's at least what I got from talking to a professional). One clue to find out whether you are predisposed is if you have someone in the family (related genetically) who has at-birth mental health issues. Then stay a gazillion miles clear of any drugs.
> My understanding is that schizophernia is a predisposed condition. Cannabis can trigger it but not really cause it. If something is flammable, and so predisposed to burning, and you hold a lit match to it, you did cause the fire. You didn't just trigger it.
There's a really interesting line of research that suggests Schizophrenia is a spectrum, rather than a binary. Lots of people have personality traits that are similar to schizophrenics or have genetic risk factors for the condition. Some of those people develop the full disorder, and some don't. There's evidence that the reason for the split is that psychosis is itself damaging. Once someone has a psychotic episode,…
There's a really interesting line of research that suggests Schizophrenia is a spectrum, rather than a binary. Lots of people have personality traits that are similar to schizophrenics or have genetic risk factors for the condition. Some of those people develop the full disorder, and some don't. There's evidence that the reason for the split is that psychosis is itself damaging. Once someone has a psychotic episode,…
Spectrum is not the opposite of binary. You probably mean gradient, from your context.
This is more than just a pedantic observation. Autism spectrum disorder is often misconstrued by the general public as a gradient, which is not accurate.
There's a really interesting line of research that suggests Schizophrenia is a spectrum, rather than a binary. Lots of people have personality traits that are similar to schizophrenics or have genetic risk factors for the condition. Some of those people develop the full disorder, and some don't. There's evidence that the reason for the split is that psychosis is itself damaging. Once someone has a psychotic episode,…
You have these cells in your brain called Microglia. They are responsible for cleaning up neurons and plaques and other weird proteins. These Microglia are activated by the firing neurons which release 2-AG and AEA (Anadamide). AEA binds to the CB1 receptor in these Microglia. 2-AG binds to CB2. THC binds to CB1. CBD binds to CB2. Autistic adults have significantly low blood serum levels of AEA. Autistic people’s neu…
Do you know of any literature I can read about the mechanisms behind this?
You have these cells in your brain called Microglia. They are responsible for cleaning up neurons and plaques and other weird proteins. These Microglia are activated by the firing neurons which release 2-AG and AEA (Anadamide). AEA binds to the CB1 receptor in these Microglia. 2-AG binds to CB2. THC binds to CB1. CBD binds to CB2. Autistic adults have significantly low blood serum levels of AEA. Autistic people’s neu…
Empirically (based on my own observations) I've known for decades that weed induced episodes in schizophrenic people. I didn't know it was helpful for autistic people. On the same (personal observation) basis, I'd say that schizophrenic people are drawn to cannabis. I have no idea why; perhaps because they're often very marginalized and precarious.
With enough dose anyone can become psychotic on THC.
Earlier quoted context omitted.
Empirically (based on my own observations) I've known for decades that weed induced episodes in schizophrenic people. I didn't know it was helpful for autistic people. On the same (personal observation) basis, I'd say that schizophrenic people are drawn to cannabis. I have no idea why; perhaps because they're often very marginalized and precarious.
Schizophrenia is a disease, not a "type of people". With enough dose anyone can become psychotic on THC.
You have these cells in your brain called Microglia. They are responsible for cleaning up neurons and plaques and other weird proteins. These Microglia are activated by the firing neurons which release 2-AG and AEA (Anadamide). AEA binds to the CB1 receptor in these Microglia. 2-AG binds to CB2. THC binds to CB1. CBD binds to CB2. Autistic adults have significantly low blood serum levels of AEA. Autistic people’s neu…
> Autistic adults have significantly low blood serum levels of AEA. Autistic people’s neurons prune slower. Schizophrenic people’s neurons prune faster. These are all group-level findings, meaning they aren't true for every individual. You can do a study and find that there is a statistically significant difference in mean X between two samples – autistic vs control or schizophrenic vs control. But pretty much always…
Now, clearly, mainstream psychology disassociated these terms sometime in the 60s, when the goal with autism diagnoses was moreso to find and identify "abnormal" children (Hans Asperger famously used Autism diagnoses to euthanize children, that's who "Asperger's Syndrome" is named after!), and Schizophrenia gained its own separate classification. But its interesting to note that there was a time when social disaffection in general was considered a single set of disorders.
Earlier quoted context omitted.
> Once someone has a psychotic episode, they are much likelier to have more. An anecdotal observation of this in media is when comedian Owen Benjamin took a "Stars of Death" edible on the Joey Diaz podcast. It was argued that this was the point his big break with reality occurred (delusions and conspiracy seen everywhere). Another interesting observation is that THC seems to intensify the effect of amphetamines like…
Plus that combo gives guaranteed insomnia. The user wakes up from whatever sleep they did get, takes the speed again, and it's like nothing happened. This continued loss of sleep compounds over time and can contribute to psychosis.