Infinitely big little numbers
Academia has rediscovered itself
Signal attenuation, a byproduct of entropy, due to generational churn means there's little guarantee.
Occam's Razor; Karpathy knows the future or he is self selecting biology trying to avoid manual labor?
His statements have more in common with Nostradamus. It's the toxic positivity form of "the end is nigh". It's "Heaven exists you just have to do this work to get there."
Physics always wins and statistics is not physics. Gamblers fallacy; improvement of statistical odds does not improve probability. Probability remains the same this is all promises of some people who have no idea or interest in doing anything else with their lives; so stay the course.