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What can mRNA treat next?

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Re: What can mRNA treat next?

#161

Post by karmelapple »

spurgu wrote: post #155
lucb1e wrote: post #134

Because it's buried in some two thousand words: > helping cells produce tissue to heal from events such as cardiac arrest > beyond simple vaccines [...] mRNA therapeutics might be tailored to instruct a person’s immune system to fight their specific type of cancer, or target protein deficiencies in specific organs, and without the toxic side effects of traditional medications. > “My personal moonshot is snake venom,…

I think another key takeaway is that mRNA didn't really seem to interest anyone until the pandemic came along.

When you say anyone, do you mean anyone with massive funds to finance a big effort with mRNA? Because that would also be wrong. This comment is either just wrong, or at least missing some very important context.

There’s a massive amount of research about mRNA. Gene therapy, vaccines, lots more. And there was money already sunk in to have mRNA vaccines at a proof of concept stage before the pandemic. There just never was the urgency to use mRNA in a vaccine until the last 15 months.

But mRNA research is all over the place, and not just in vaccines.

Source: my life scientist partner

Edit: Google search for RNA institute turns up lots of results at universities all over the place: https://www.google.com/search?hl=en&q=institute%20for%20rna%...

Re: What can mRNA treat next?

#162

Post by jonstewart »

alcuadrado wrote: post #160

> Derrick Rossi doesn’t quite see it this way, but he kind of saved the world. > > In 2008, he began researching messenger RNA (mRNA), building on the long-ignored work of Hungarian researcher Katalin Karikó What?! Katalin Karikó is an SVP at BioNTech, the lab that created Pfizer's vaccine.

Yes, and... she was long ignored before that.

https://www.statnews.com/2020/11/10/the-story-of-mrna-how-a-... https://www.nytimes.com/2021/04/08/health/coronavirus-mrna-k...

Re: What can mRNA treat next?

#164

Post by da02 »

Isn't it too early to think about mRNA therapies?

VAERS data released today showed 118,902 reports of adverse events following COVID vaccines, including 3,544 deaths and 12,619 serious injuries between Dec. 14, 2020 and April 23, 2021: https://childrenshealthdefense.org/defender/vaers-significan...

The Orange County Coroner's office is investigating the death of a woman who died just days after she received her second dose of the Moderna vaccine: https://abc7.com/health/oc-womans-death-after-vaccination-sp...

Meanwhile: Using a protocol of zinc, hydroxychloroquine or ivermectin and one antibiotic in combination with inhaled budesonide and/or intramuscular dexamethasone... The early ambulatory treatment regimen was associated with estimated 87.6% reduction in hospitalization and 74.9% reduction in death (phttps://trialsitenews.com/texas-physician-researchers-case-s...

Re: What can mRNA treat next?

#165

Post by halfjoking »

throwaway879 wrote: post #137
throwaway879 wrote: post #129

Do the concerns raised here have any merit? https://osf.io/epr24/

Why would anyone down-vote a question asking if there is any merit to some concerns raised by a clinical researcher? The target audience is people working on mRNA vaccines who might be able to shed some light.

I'm with you.

I have no idea why people don't question anything about the capabilities/consequences of this tech.

Re: What can mRNA treat next?

#166

Post by stbtrax »

da02 wrote: post #164

Isn't it too early to think about mRNA therapies? VAERS data released today showed 118,902 reports of adverse events following COVID vaccines, including 3,544 deaths and 12,619 serious injuries between Dec. 14, 2020 and April 23, 2021: https://childrenshealthdefense.org/defender/vaers-significan... The Orange County Coroner's office is investigating the death of a woman who died just days after she received her secon…

How would an antibiotic help with a viral infection? Might as well start using some essential oils and homeopathy. If that regimen actually worked, we'd probably see it more widely used and studied.

They investigate each death reported to VAERS to see if it was actually vaccine related. Given how many millions of doses were given out, and especially to people that were already old or clinging on to life, 3,544 is not unexpected. None of those were directly attributable to the vaccine.

Re: What can mRNA treat next?

#167

Post by soared »

da02 wrote: post #164

Isn't it too early to think about mRNA therapies? VAERS data released today showed 118,902 reports of adverse events following COVID vaccines, including 3,544 deaths and 12,619 serious injuries between Dec. 14, 2020 and April 23, 2021: https://childrenshealthdefense.org/defender/vaers-significan... The Orange County Coroner's office is investigating the death of a woman who died just days after she received her secon…

Please don’t play armchair medical researcher. The question you’ve asked is much larger 3 urls, one of which is an investigation into a single event among hundreds of millions of doses.

Your third link is not remotely relevant. The article is not discussing covid treatments, but rather the category of vaccine. Zinc isn’t going to cure cancer.

Re: What can mRNA treat next?

#168

Post by r3pl4y »

zaphod12 wrote: post #130
r3pl4y wrote: post #126

#ExplainLikeImFive Could somebody explain to me what a PVC (Personalized Cancer Vaccine) is? Like what is the personalized part in there? Is there really a realistic scenario in which we'll get some regular vaccination and then we'll be cancer free in the future?

Ok, so cancer is essentially a blanket term for describing that you have a group of cells in your body doing uncontrollable runaway mitosis (replicating themselves). But the thing is that it's caused by hundreds of different mutations to your cells in thousands of combinations. So developing a single way to combat all of this is super hard. But if we can identify your particular set of mutations and train your body t…

Thank you very much

Re: What can mRNA treat next?

#169

Post by da02 »

stbtrax wrote: post #166
da02 wrote: post #164

Isn't it too early to think about mRNA therapies? VAERS data released today showed 118,902 reports of adverse events following COVID vaccines, including 3,544 deaths and 12,619 serious injuries between Dec. 14, 2020 and April 23, 2021: https://childrenshealthdefense.org/defender/vaers-significan... The Orange County Coroner's office is investigating the death of a woman who died just days after she received her secon…

How would an antibiotic help with a viral infection? Might as well start using some essential oils and homeopathy. If that regimen actually worked, we'd probably see it more widely used and studied. They investigate each death reported to VAERS to see if it was actually vaccine related. Given how many millions of doses were given out, and especially to people that were already old or clinging on to life, 3,544 is not…

Maybe the antibiotic is for Tuberculosis? https://www.cdc.gov/globalhealth/stories/2020/tb-covid.html

Re: What can mRNA treat next?

#170

Post by da02 »

soared wrote: post #167
da02 wrote: post #164

Isn't it too early to think about mRNA therapies? VAERS data released today showed 118,902 reports of adverse events following COVID vaccines, including 3,544 deaths and 12,619 serious injuries between Dec. 14, 2020 and April 23, 2021: https://childrenshealthdefense.org/defender/vaers-significan... The Orange County Coroner's office is investigating the death of a woman who died just days after she received her secon…

Please don’t play armchair medical researcher. The question you’ve asked is much larger 3 urls, one of which is an investigation into a single event among hundreds of millions of doses. Your third link is not remotely relevant. The article is not discussing covid treatments, but rather the category of vaccine. Zinc isn’t going to cure cancer.

You can call me whatever names you want, but I believe the core disagreement is your approach is cure/treatment and I'm looking at the root cause/prevention. This is not to suggest zinc deficiency is the culprit, but various deficiencies in the American high calorie diet. From the NIH.gov website:

"Evolving and compelling evidence exists that proves that zinc is implicated as an important cytotoxic/tumor suppressor agent in several cancers. For example, that cellular zinc levels are markedly decreased in prostate cancer is well established" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291177/

Zinc: A promising agent in dietary chemoprevention of cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102454/

"Many epidemiological studies have shown a relationship between the zinc content in the diet and the risk of cancer" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835436/

" In addition, zinc contributes to the truncation of the Krebs cycle and inhibition of citrate oxidation, which further prevents cancer cell growth and proliferation, as well as inhibiting the invasion and migration of cancer cells" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216164/

"The present meta-analysis suggested that serum zinc levels were significantly lower in lung cancer patients than that in controls." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503426/

"In conclusion, we found that highest category of dietary zinc intake can significantly reduce the risk of pancreatic cancer, especially among American populations." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463257/

"Increased risk of cancer mortality associated with cadmium exposures in older Americans with low zinc intake" https://pubmed.ncbi.nlm.nih.gov/23151207/

And the list continues: https://www.google.com/search?q=nih.gov+zinc+cancer

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