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New‐onset autoimmune phenomena post‐Covid‐19 vaccination

onlinelibrary.wiley.com

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Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#151
post #61

They should have some kind of "can't remove from headline" disclaimers for papers like this to keep them from fueling idiocy. This paper lays out in it's intro that it will make no attempt to find causation, yet in media this headline will be used almost exclusively to prove that point.

If you read the paper it discusses causal mechanisms extensively. Reality is you can't get a paper about vaccine side effects out, or keep it out, unless you grovel in the intro and state that vaccines are wonderful, safe and everyone should take them. Skip the obligatory morality disclaimer at the start and you'll see lots of case studies where causality is obvious, along with discussions of how it works, e.g.

"A 67-year-old patient from Hispanic had petechial rashes on her legs and chest 2 weeks after receiving the first dose of COVID-19 vaccine (Pfizer-BioNTech). Then, she received the second dose of the vaccine two days prior to developed bleeding in her gums, a rapid rash covering her body and a subconjunctival haemorrhage in the right eye"

...

"There are several putative mechanisms by which COVID-19 vaccine triggers immune thrombotic thrombocytopenia (ITT). First, Greinacher and colleagues considered that COVID-19 vaccination causes a rare ITT mediated by activation of antibodies against PF4 that stimulate platelets through their Fcγ receptors"

...

"First, an interval of 1–3 weeks between vaccination and the onset of symptoms supports a temporary causal relationship"

...

"For instance, a 30-year-old man, without family history of kidney disease, developed fevers, headache and brown-coloured urine, coupled with new-onset haematuria and proteinuria 1 day after vaccination, eventually diagnosed with IgA nephropathy"

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#152

Earlier quoted context omitted.

Quoted post unavailable.

Incredibly disappointing to see foxhop's comments flagged and dead, while pickledhotdog's snark lives on. https://news.ycombinator.com/newsguidelines.html is worth a read. "Don't be snarky." "Please don't sneer, including at the rest of the community." "Comments should get more thoughtful and substantive, not less, as a topic gets more divisive." "When disagreeing, please reply to the argument instead of calling name…

Thanks for the reading suggestion

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#153

Earlier quoted context omitted.

Congrats to you and your friends. Unfortunately that's not the case for hundreds of thousands of your compatriots and millions of your fellow humans. Conflating fear mongering around vaccines with very few cases of serious side effects (none of which are contagious) with "fear mongering" around the virus itself which has caused literally millions of deaths and untold post-infection issues for millions more is what's…

You don't actually know how common vaccine side effects are, because standard practice is to assume anything that happens >7 days after a vaccine isn't caused by it. This was the standard used in the trials for example. But from the paper: "the mean time to onset of symptoms [for VITT] after vaccination is 8 days ... The mean time to onset of symptoms after vaccination [for auto immune hepatitis] is 13 days, ranging…

Surely we can deduce whether there are meaningful numbers of serious side effects by looking at past years in population data - especially in populations that have high vaccination rates. If rates have increased markedly, then there's obviously something to investigate. But as noted elsewhere, the rates seem to be 'in line' with pre-vaccine rates for a fair few side effects in a given population. They just get more press now because of the focus on health issues in the media and the hysteria around "vaccine injuries"

You'll get no argument from me that reporting standards leave a bit to be desired. The trials are the trials - they could be improved, sure - but side effect reporting didn't end with trials. Plenty of governments kept tabs on side effects post vaccine once they were being widely administered

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#154

Earlier quoted context omitted.

I'm just an anecdote, but I've had COVID. It was less than a bad case of the flu. To pretend that it affects everyone equally and that they're all the worst thing ever is malpractice. Risk communication should always have been striated by age/comorbidity and let people make decisions from there.

I’ve had it to, after I was vaccinated. The thing is, you don’t know ahead of time how it will affect you. There are lots of examples of 30 something, fit, athletic even, people with no preexisting conditions, getting very sick and hospitalized, dying, or ending up with long COVID. Beyond that, many people who are sick with it won’t quarantine themselves for 10 days or wear masks and end up infecting others —- assumi…

While true, there are also examples with vaccine reactions.

There's a hell a lot of selfishness going on by people demanding perfect security and therefore whole industries to be shut down.

I am vaccinated and get tested at least 3 times a week because I still have contact to others, but the selfishness doesn't just affect on position in this debate.

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#155
post #37
post #32

Earlier quoted context omitted.

But they aren’t in the same magnitude - for example, incidences of peri/myocarditis is 30x (at a minimum) greater in someone who has COVID vs someone vaccinated; and vaccination leads to shorter milder breakthrough infections which (should - I can’t claim to have seen a study) lead to a lower incidence compared to someone who was unvaccinated and infected

Yes, that’s my doubt as well. Until we have more unbiased studies coming out, we can’t determine the impact of these side effects. The problem with pro-vaccine propaganda is that it tells you to blindly listen to the science. The problem with that is “the science” is controlled by commercial interests and profit margins. It’s like telling everyone democracy is the One True Way and we end up in last-stage capitalism.

If you would of made this comment in the 70's or 80's you would have been called a commie bastard. You manage in just two sentences to conflate 3 different notions into one single "bad thing ™": science, capitalism and democracy.

Democracy does not equal/result in/require/corelate with/mean the same as/etc. capitalism. Before Marx, the very vast majority of non-democratic regimes have been capitalist.

There is no such thing as "the science" to people engaged in doing science. "The science" is only a concept for people who stay away from scientific pursuit. There is a thing called scientific consensus that means the collection of knowledge scientists widely agree best describes reality at a given moment in time.

The scientific consensus is not controlled by commercial interests for many reasons. Among those reasons here are just two: plenty of science is publicly funded and the scientific consensus is global therefore being beyond the capabilities of any single entity to direct. Individual scientists may be biased, but that bias is not coherent in the population of scientists.

In the case of Covid vaccines, even if "the science" was controlled by commercial interests, that would still not result in a conspiracy. There are 20+ vaccines and each manufacturers commercial interest would be to discredit competitors and sell more of their own.

The scientific consensus is pro-vaccine because vaccines have been prooven repeatedly in the past 100+ years to result in higher quality and longer duration of life. There is no consensus on which vaccine is better (for various definitions of better). But there is consensus that covid vaccines are the best tools humanity has for the foreseeable future to fight against the pandemic. And there is consensus that they are orders of magnitude safer than the disease.

Also, there is no blind single mindedness. The very reason you know about all of the side effects that have surfaced so far is because science was done. If "the science" was controlled, the featured article would not exist. We have known about the existence of side effects of vaccines since the start. Side effects were predicted and expected since before the vaccines existed, because all medication has side effects. They have been measured, and continue to be measured. This study is just one step on our quest to ever more precisely measure those side effects. So, yes, the impact of the side effects has been sufficiently determined to conclude that at the very least vaccination against covid is orders of magnitude safer than the risk of covid itself.

The the confusion you display by corelating such different notions in your comment, shows you have bought a narrative peddled by some grifters, hook, line and sinker. The same as all the people deceived to believe that the MMR vaccine causes autism.

Be sincere with yourself and admit that, at this point in time, the only studies you will consider unbiased are those that will confirm your own bias, namely that you consider the side effects of covid vaccines to be too risky.

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#156
post #75

Earlier quoted context omitted.

I'm responding with anger, thus I ask for mercy and understanding. I used to be one of the authors of that science. I spent 7 years of my life working on it. For this my take-home pay was close to the poverty line. I was qualified for a ~500K/year job at FANG. That's a heavy sacrifice, not commercial interest and profit margins.

Your anger is misplaced. You assume I’m talking about individuals; I’m blaming capitalist corporations. Science is not a person, it is a process that involves innumerable functions of people - only one of which are the actual scientists. A great example is the Boeing MAX scandal, where management ignored the engineers and pushed ahead. To be clear, I’m accusing Pfizer et all of corruption. And given their history, I…

Yunohn, you are the one who used the term "the science" which you consider controlled by corporate interests. Mellavora's anger at your comment is justified since at the very least you were directly accusing them of being complicit. You are weaseling out.

Pfizer, can be corrupt, and price gouge, and be the perpetrator of various other evils. That does not change the fact that the vaccine they are mass producing based on research done by BioNTech, is ammong the most effective and safest of the 20+ vaccines. And that all of the available vaccines are vastly safer than the disease.

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#157
post #75

Earlier quoted context omitted.

Your anger is misplaced. You assume I’m talking about individuals; I’m blaming capitalist corporations. Science is not a person, it is a process that involves innumerable functions of people - only one of which are the actual scientists. A great example is the Boeing MAX scandal, where management ignored the engineers and pushed ahead. To be clear, I’m accusing Pfizer et all of corruption. And given their history, I…

Yunohn, you are the one who used the term "the science" which you consider controlled by corporate interests. Mellavora's anger at your comment is justified since at the very least you were directly accusing them of being complicit. You are weaseling out. Pfizer, can be corrupt, and price gouge, and be the perpetrator of various other evils. That does not change the fact that the vaccine they are mass producing based…

> You are weaseling out.

Thanks for telling me what I meant. But I did not mean that, and the square quotes were intentional. It’s a way of speaking that’s quite widely accepted, and referring to a phenomenon rather than individuals. Surely this is not new to you? Like when someone criticises an authority’s decision, the blame is on the decision makers, not the line workers.

Not much to respond to the rest of your comment - I wasn’t telling people to not get the vaccine, and I’m fully vaccinated myself. I’m emphasising the value of skepticism and questioning authority. Cheers!

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#158

Earlier quoted context omitted.

You don't actually know how common vaccine side effects are, because standard practice is to assume anything that happens >7 days after a vaccine isn't caused by it. This was the standard used in the trials for example. But from the paper: "the mean time to onset of symptoms [for VITT] after vaccination is 8 days ... The mean time to onset of symptoms after vaccination [for auto immune hepatitis] is 13 days, ranging…

Surely we can deduce whether there are meaningful numbers of serious side effects by looking at past years in population data - especially in populations that have high vaccination rates. If rates have increased markedly, then there's obviously something to investigate. But as noted elsewhere, the rates seem to be 'in line' with pre-vaccine rates for a fair few side effects in a given population. They just get more p…

But again, you don't know what the true current side effect rate is because it's not being measured honestly. There's a dropbox for people to write in and say they were injured:

https://openvaers.com/covid-data/mortality

which isn't nothing but all such reports are dismissed as coincidences or trolling. That's very unlikely to be the case, but even if you accept that argument, it means governments are forcing the entire population to take brand new drugs on the back of "drug firms assure us there are no long term side effects where long term means more than a week", which beyond being incredibly dishonest, would also be incredibly risky. Asteroids crashing into Earth or nuclear wars have nothing on governments forcing everyone to take a dangerous substance because they blindly trusted the makers.

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#159
post #157

Earlier quoted context omitted.

Yunohn, you are the one who used the term "the science" which you consider controlled by corporate interests. Mellavora's anger at your comment is justified since at the very least you were directly accusing them of being complicit. You are weaseling out. Pfizer, can be corrupt, and price gouge, and be the perpetrator of various other evils. That does not change the fact that the vaccine they are mass producing based…

> You are weaseling out. Thanks for telling me what I meant. But I did not mean that, and the square quotes were intentional. It’s a way of speaking that’s quite widely accepted, and referring to a phenomenon rather than individuals. Surely this is not new to you? Like when someone criticises an authority’s decision, the blame is on the decision makers, not the line workers. Not much to respond to the rest of your co…

What are you talking about? You consider "the science" to be e phenomenon? What does that even mean?

Also, plenty of people who are (voluntarily or involuntarily) spreading FUD are not directly telling others to do or not do something. They are just asking questions. And keep asking the same questions even after they have received answers repeatedly. It is still spreading FUD.

Skepticism and questioning authority is good, spreading FUD is not.

Re: New‐onset autoimmune phenomena post‐Covid‐19 vaccination

#160
post #157

Earlier quoted context omitted.

> You are weaseling out. Thanks for telling me what I meant. But I did not mean that, and the square quotes were intentional. It’s a way of speaking that’s quite widely accepted, and referring to a phenomenon rather than individuals. Surely this is not new to you? Like when someone criticises an authority’s decision, the blame is on the decision makers, not the line workers. Not much to respond to the rest of your co…

What are you talking about? You consider "the science" to be e phenomenon? What does that even mean? Also, plenty of people who are (voluntarily or involuntarily) spreading FUD are not directly telling others to do or not do something. They are just asking questions. And keep asking the same questions even after they have received answers repeatedly. It is still spreading FUD. Skepticism and questioning authority is…

If you think I’m absurd for questioning authority and skepticism in situation where profits are astronomical and will be enforced by governments, I have a bridge to sell you.

Regardless, I can tell in your reply that you think of me as a kook, conspiracy theorist. Gday!

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