141–150 of 214 posts
This seems to bolster the theory that autism is modulated by the gut-brain axis. Being given antibiotics at such an early age will probably severely dysregulation gut microbiota. And GABA actually does cross the BBB but in small amounts. Perhaps at such an early age, dysregulation in GABA produced in the gut has significant effects on brain health - over stimulation, learning memory issues, etc.
This seems to bolster the theory that autism is modulated by the gut-brain axis. Being given antibiotics at such an early age will probably severely dysregulation gut microbiota. And GABA actually does cross the BBB but in small amounts. Perhaps at such an early age, dysregulation in GABA produced in the gut has significant effects on brain health - over stimulation, learning memory issues, etc.
The gut microbiota shouldn't be affected by antibiotics delivered via IV.
I don't have much on the way of valuable insights or conversation starters, I just think this story is sweet and these 2 brothers obviously love the hell out of each other, made me happy to read :)
Reading your comment made me actually want to read the article in question and I am super glad I did.
Emotionally, probably a best reminder of familial love in a world filled with indifference and often hate
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Reading the article, it turns out the one twin who is "more autistic" had a hole in his heart that surgery had to correct. So I suspect the actual issue here is something simpler like a difference in brain development because of the difference in the amount of blood flow.
This is Hackernews, where all major health issues are traceable to the gut.
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Why would that correlate?
> Christian Scientists avoid almost all medical treatment, relying instead on Christian Science prayer. https://en.wikipedia.org/wiki/Christian_Science#Healing_prac...
This seems to bolster the theory that autism is modulated by the gut-brain axis. Being given antibiotics at such an early age will probably severely dysregulation gut microbiota. And GABA actually does cross the BBB but in small amounts. Perhaps at such an early age, dysregulation in GABA produced in the gut has significant effects on brain health - over stimulation, learning memory issues, etc.
"The infection was from drug-resistant staph bacteria. So John went back to the hospital and spent a month on powerful antibiotics pumped directly into a vein near his heart."
There are so many confounding factors here. Could be no connection to the episode whatever. Could be that the infection that required the antibiotics contributed to the autism. Could be the antibiotics contributed directly. Could be the overall trauma of the surgery, treatment and recovery.
Seems like the gut thing is the least likely culprit and requires quite a lot of creativity to even consider it.
Earlier quoted context omitted.
> Being given antibiotics at such an early age will probably severely dysregulation gut microbiota. It’s extremely common for young kids to receive antibiotics. In some countries, antibiotics are over the counter and many parents will give their kids antibiotics for nearly any infection. Antibiotic misuse is rampant in some countries where they aren’t gated behind prescriptions. Any such link with autism would theref…
«So John went back to the hospital and spent a month on powerful antibiotics pumped directly into a vein near his heart.» This is not «extremely common».
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The term is being used in reference to their genes, not their appearance.
I'll mirror what someone else said, have they actually sequenced them? Clearly a lot of changes happened at a very early state, mutations, so why should we expect their genetic makeup to be identical?
In animals and human chimeras, this means an individual derived from two or more zygotes, which can include possessing blood cells of different blood types, and subtle variations in form (phenotype).
https://en.wikipedia.org/wiki/Chimera_(genetics)
For example, in 2002, news outlets reported the story of a woman named Karen Keegan, who needed a kidney transplant and underwent genetic testing along with her family, to see if a family member could donate one to her. But the tests suggested that genetically, Keegan could not be the mother of her sons. The mystery was solved when doctors discovered that Keegan was a chimera—she had a different set of DNA in her blood cells compared to the other tissues in her body.
https://www.scientificamerican.com/article/3-human-chimeras-...