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Vitamin D and Depression (2020)

ncbi.nlm.nih.gov

141–150 of 221 posts

Re: Vitamin D and Depression (2020)

#141

Earlier quoted context omitted.

Had a consult with a sleep doctor, he stressed the importance of getting out for morning light for at least 30 minutes with no sunglasses.

Why no sunglasses?

Morning light hitting your eyes has a significant psychological impact. Sunglasses cut way down on that. It’s discussed in one of Huberman’s sleep related podcast episodes if you’re interested

Re: Vitamin D and Depression (2020)

#142

Earlier quoted context omitted.

I live in Seattle and have been depressed for a while. I had my Vitamin D3 levels checked via blood test, and they were really low. Started taking 5,000 IU per day, and I feel exactly the same as before.

To answer a bunch of questions: Yes, I had bloodwork done later showing my D3 level in the typical range. Whether that was due to the supplement, or diet, or lifestyle I can't say. I take 1 pill (USP certified) on average 2-3x per week. So not every day. I've got treatment resistant depression and have tried probably everything else you're about to suggest. The only thing that kind of helped was dihydrotestosterone,…

Did you try vorinostat yourself to treat depression, or was it coincidental? I never heard of that for depression, but looking at the mechanism it can make sense-- some HDAC inhibitors have powerful effects on mental issues

Re: Vitamin D and Depression (2020)

#143
post #70

Vitamin D supplementation didn't affect my depression. Going for walks to get more sunlight made it worse. I understand that not everything works for everyone and I wish those around me, including my doctor, did as well so they'd stop blaming me when their "cure" doesn't work on me.

Would you mind sharing in what ways going for walks made it worse for you?

I found going for walks during lockdown to be depressing. Always the same few streets (yes I'd try various directions but it doesn't take long to have walked down every street within 30 minutes of you). My mom lives in the suburbs. She goes for walks but they are hardly uplifting "same walk I've made 400 times before" type of thing. I'd even say walking makes more feel more alone then when I'm at home alone because at least at home I can watch TV/movies/play game and write comments to strangers on HN.

Re: Vitamin D and Depression (2020)

#144

Earlier quoted context omitted.

>> The medical community is full of contradictions. We added iodine to salt to prevent deficiency, then decades later told everyone to avoid salt. I've found iodine to be a huge piece of the puzzle - certainly not a panacea but one of several go to solutions.

The American Heart Association recommends no more than 1500 milligrams of sodium per day. Because sodium is being added to packaged and processed foods, the average American was getting way more sodium than the recommended amount. And given the number of obese people and those with hypertension who are salt-sensitive, lots of people were getting way more sodium than was healthy for them.

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Re: Vitamin D and Depression (2020)

#145

Earlier quoted context omitted.

And yet lots of dermatologists will tell you to avoid sunlight. The medical community is full of contradictions.

>> The medical community is full of contradictions. We added iodine to salt to prevent deficiency, then decades later told everyone to avoid salt. I've found iodine to be a huge piece of the puzzle - certainly not a panacea but one of several go to solutions.

Cranberries are how I get iodine into my diet. Not-from-concentrate Cranberry juice from TJs, primarily.

Re: Vitamin D and Depression (2020)

#146

Earlier quoted context omitted.

I live in Seattle and have been depressed for a while. I had my Vitamin D3 levels checked via blood test, and they were really low. Started taking 5,000 IU per day, and I feel exactly the same as before.

To answer a bunch of questions: Yes, I had bloodwork done later showing my D3 level in the typical range. Whether that was due to the supplement, or diet, or lifestyle I can't say. I take 1 pill (USP certified) on average 2-3x per week. So not every day. I've got treatment resistant depression and have tried probably everything else you're about to suggest. The only thing that kind of helped was dihydrotestosterone,…

"I've got treatment resistant depression and have tried probably everything else you're about to suggest."

I bet you haven't tried MDMA therapy.

Re: Vitamin D and Depression (2020)

#147

Earlier quoted context omitted.

Sunlight’s effects on body chemistry also have a damping effect on inflammation. It’s a funny thing. Sunlight has an impact on many chemical processes in and on the body. One example: Our skin is coated with a bunch of chemicals. There’s a number of different acidic chemicals. These are known as the “acid mantle”: https://en.wikipedia.org/wiki/Acid_mantle One of these substances is urocanic acid . The body manufactur…

Anecdata: I grew up in LA. I was always relatively healthy. Moved to NYC. Developed autoimmune disease by my 6th year in NYC. I often wonder if I would have developed the disease if I had stayed in LA.

people in the past would grab a small jar full of dirt from home and drink it whenever countering some ailment, I actually think that'd still work due to the recent researches on gut bacterial and it's influences on immune system and all...

Re: Vitamin D and Depression (2020)

#148

Earlier quoted context omitted.

This is what I'm talking about. The idea that "going for a walk and getting sunlight is good for depression" is so universally unchallengable that I must live somewhere terrible if it doesn't work for me.

Book a two week long float down the middle fork of the Salmon river and let me know how you feel after.

I don't have depression but I still feel like that'd make you depressed. Just because something is exciting to you does not mean it's meaningful to everyone

Re: Vitamin D and Depression (2020)

#150
post #43

Earlier quoted context omitted.

Is vitamin D fat soluble? If so, pretty sure it needs to be consumed with fat. That's partly why it's common in milk.

It's common in milk because it helps with calcium absorption.

This is correct:

https://www.bones.nih.gov/health-info/bone/bone-health/nutri....

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