121–130 of 217 posts
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Excedrin is the only thing besides morphine that cures my occasional but brutal headaches.
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The vaccine-autism smoking gun that Andrew Wakefield and RFK Jr. heroically tried to find has, so far, failed to turn up. But there was a study recently that showed that autism is correlated with the mother taking acetaminophen during pregnancy.
The general advice is to not take any medication during pregnancy without a physician’s advice. This includes all over the counter medicines.
Okay some don't, particularly North American and Northern/Western European ones.
But mostly, on average, physicians always try to prescribe you something.
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As with all things, the poison is in the dose. A tonne of incredibly useful medicine can kill you if dosed incorrectly.
Sure but it’s pretty easy overdose on paracetamol. Since it’s a mild and really common painkiller, sometimes seen as not dangerous, someone uneducated about it who is really suffering could easily take 3 or 4 times the dose. Unlike a lot of drugs, you are not going to have a lot of immediate side effects if you overdose on paracetamol. You’ll just horribly die some days after,
I never took Tylenol/Paracetamol/acetaminophen, or anything containing it or given it to my children. We never reduce fever below 39.5/103.1 either - risks of febrile seizures are overstated and if you're a responsible parent, not a lazy one, you can see if things are going South, but there are other traditional means to lower fever. People are just too spoiled nowadays! I tested positive with COVID-19 on Tuesday and…
Not always. Blaming “lazy” and irresponsible parents is disgusting.
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Millions of kids have been born to parents who smoked and drank all the way through their pregnancies, especially before the 1970s or so. It raises risks, but doesn’t guarantee bad outcomes.
Many, many more but here's a few you might want to start with: "The meta-analysis showed a significant association between maternal tobacco smoking during pregnancy and increased risk of ADHD in offspring." Mohammadian M, Khachatryan LG, Vadiyan FV, Maleki M, Fatahian F, et al. (2025) The association between maternal tobacco smoking during pregnancy and the risk of attention-deficit/hyperactivity disorder (ADHD) in o…
The implied causation annoys me. ADHD is hereditary, even if if the mother does not smoke. People with ADHD smoke ten times more often.
I never took Tylenol/Paracetamol/acetaminophen, or anything containing it or given it to my children. We never reduce fever below 39.5/103.1 either - risks of febrile seizures are overstated and if you're a responsible parent, not a lazy one, you can see if things are going South, but there are other traditional means to lower fever. People are just too spoiled nowadays! I tested positive with COVID-19 on Tuesday and…
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This send me into a whole rabbit hole. Mostly children get paracetamol overdose. Then I learned that in US/UK kids get paracetamol in liquid form with all kinds of flavours. Which is much harder to dose correctly when the kid spits or drools it out. Total culture shock for me, as in Europe the default for children is rectal ingestion (which is probably a culture shock as well for Americans). Any how, with pills it is…
Recently had a prescription error with my two month old baby. The doctor prescribed 7 times as much iron supplement as they intended (confusing labelling - so while I'm annoyed, I can see how it happened). This went on for a month until we uncovered the error. We had blood test done (on the doctor's recommendation), and luckily there is no sign of any damage, but prescription errors do happen (even if they are rare)…
Basically, paracetamol turns out to be mildly contraceptive, by meddling with cell division cycle. I wonder if it might also slow healing of wounds, or wherever else intense cell division happens.
Unsure if this is related, but I’ve heard that taking painkillers for delayed onset muscle soreness will reduce muscle gains.
Prostaglandins are an inflammatory hormone that do a variety of things, but specifically PGE2 plays a role in muscle stem cell activation to divide and produce more muscle fibers. The effect is probably realistically small, but you will leave gains on the table by taking ibuprofen after hard workouts.
It's probably worth mentioning that this drug is called Acetaminophen in the US, and is the active ingredient in Tylenol and other over the counter medicines.
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This send me into a whole rabbit hole. Mostly children get paracetamol overdose. Then I learned that in US/UK kids get paracetamol in liquid form with all kinds of flavours. Which is much harder to dose correctly when the kid spits or drools it out. Total culture shock for me, as in Europe the default for children is rectal ingestion (which is probably a culture shock as well for Americans). Any how, with pills it is…
> as in Europe the default There's no “as in Europe”, every European country is different. In France the default is also liquid form, but the pipette is graduated is kilograms of baby weight, which limit the errors you can make (you know your kid doesn't weight 15kg when his weight is around 8).
I think the mistakes also come when the child spits out part of the liquid, and parents give another dose.