One thing people talk about is the short-lived effects of DMT, and how they would like more time in the the DMT space. But as I understand it, your body doesn't build up a resistance to it. The DMTx [0] project is seeking to exploit this property and created extended-state DMT experiences using some basic medical techniques. Also, they are looking for volunteers. [0]: https://www.dmtx.org
Why can't they just use an intravenous drip?
A DMT trip 'feels like dying' – and scientists now agree
111–120 of 142 posts
Re: A DMT trip 'feels like dying' – and scientists now agree
#112> “There is nothing here to begin to enable us to propose that on DMT, you literally transcend the laws of this universe and do actually go to another world,” he says. This is faulty thinking. An afterlife doesn’t presuppose a violation of natural laws, or a separate world. It just means you continue living in a different form. The only thing that would be required for that is a causal relationship (yet to be observe…
Thank you for sharing. I think too often we assume the concept of an "afterlife" implies some kind of supernatural or religious phenomenon. Since we don't have proof of it I can't say I definitely believe such a thing exists, but I certainly believe it's possible. If there is an "afterlife" I believe it fits into our natural laws and can be explained and observed scientifically - we just haven't discovered all of the…
There is plenty of evidence out there that points to something odd going on; the challenge lies in getting more skeptics to seriously evaluate it. Some HNer years ago turned me onto the book Irreducible Mind, whose last hundred pages or so is a bibliography of evidence for this kind of thing provided by people who say “I don’t believe it, but I can’t explain it.” But a lot of that evidence comes from skeptics testing exceptional individuals, and James Randi did a good job of showing how fakers can fool scientists, so I can’t really say how reliable it is other than as a jumping-off point for further study.
I came across an interesting and more rigorous set of studies done recently on how consciousness can influence quantum effects. They had observers try to influence the amount of interference generated by the double-slit experiment, and have repeatedly under various conditions gotten a significant effect. Perhaps most interesting is that while all humans had an effect, the meditators reliably outperformed the non-meditators. The setup is simple enough that it’s just begging for replication.
Here’s the video link for any curious folks. Skip the first 5 minutes which is just a refresher on what the double slit experiment is:
Re: A DMT trip 'feels like dying' – and scientists now agree
#113> “There is nothing here to begin to enable us to propose that on DMT, you literally transcend the laws of this universe and do actually go to another world,” he says. This is faulty thinking. An afterlife doesn’t presuppose a violation of natural laws, or a separate world. It just means you continue living in a different form. The only thing that would be required for that is a causal relationship (yet to be observe…
> The only thing that would be required for that is a causal relationship (yet to be observed in science) between your dying mind and some other living structure.
Especially this part is phrased so accurately. Of course we are yet to observe anything similar to it either. Something that survives death and is capable of supporting thought. It would have to be something material, right?
Re: A DMT trip 'feels like dying' – and scientists now agree
#114One thing people talk about is the short-lived effects of DMT, and how they would like more time in the the DMT space. But as I understand it, your body doesn't build up a resistance to it. The DMTx [0] project is seeking to exploit this property and created extended-state DMT experiences using some basic medical techniques. Also, they are looking for volunteers. [0]: https://www.dmtx.org
Why can't they just use an intravenous drip?
> "Using pharmacokinetic modeling and DMT blood sampling data, we demonstrate that the unique pharmacological characteristics of DMT, which also include a rapid onset and lack of acute tolerance to its subjective effects, make it amenable to administration by target-controlled intravenous infusion. This is a technology developed to maintain a stable brain concentration of anesthetic drugs during surgery."
[0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944667/
edit: I guess that isn't a drip. I know nothing about this sort of thing :)
Re: A DMT trip 'feels like dying' – and scientists now agree
#115I just associate DMT with nausea — and have no desire to repeat that pain. I did an ayuasca ceremony and only managed to drink one dose (you are encouraged to drink a lot more) — but my body felt so awful and all the evidence suggested the pretty obvious cause that there was no part of me that wanted to drink more and I felt completely fine with my decision to stop.
Re: A DMT trip 'feels like dying' – and scientists now agree
#116Earlier quoted context omitted.
ayuasca and smoked DMT are too very different experiences.
Yes. And the article didn't make that clear enough. The biological lifetime of DMT is very short, because there are enzymes (monoamine oxidase aka MAO) in many tissues. So the effects last 15-30 minutes. But ayahuasca includes MAO inhibitors, so the effects can last for many hours. And it's mainly the MAO inhibitors that make users feel ill.
Re: A DMT trip 'feels like dying' – and scientists now agree
#117One thing people talk about is the short-lived effects of DMT, and how they would like more time in the the DMT space. But as I understand it, your body doesn't build up a resistance to it. The DMTx [0] project is seeking to exploit this property and created extended-state DMT experiences using some basic medical techniques. Also, they are looking for volunteers. [0]: https://www.dmtx.org
Re: A DMT trip 'feels like dying' – and scientists now agree
#118One thing people talk about is the short-lived effects of DMT, and how they would like more time in the the DMT space. But as I understand it, your body doesn't build up a resistance to it. The DMTx [0] project is seeking to exploit this property and created extended-state DMT experiences using some basic medical techniques. Also, they are looking for volunteers. [0]: https://www.dmtx.org
That sounds awesome. I wish I could pay to lie in a hospital bed and have a medical professional administer intravenous DMT just for a short period (at least initially). Hopefully this work will bring us closer to a world where supervised DMT voyages are available to the public.
Re: A DMT trip 'feels like dying' – and scientists now agree
#119Earlier quoted context omitted.
Yes. And the article didn't make that clear enough. The biological lifetime of DMT is very short, because there are enzymes (monoamine oxidase aka MAO) in many tissues. So the effects last 15-30 minutes. But ayahuasca includes MAO inhibitors, so the effects can last for many hours. And it's mainly the MAO inhibitors that make users feel ill.
Changa includes rima (hamalas from b.capii) and lasts around an hour if good. And No nausia or effect from food.
I used to have a book about ayahusca-like formulations, using plants from various continents. But I've forgotten the name. Basically, many plants contain DMT, and many others contain MAO inhibitors. Also, I believe that one can combine some MAO inhibiting antidepressants, such as selegiline, with DMT.
Re: A DMT trip 'feels like dying' – and scientists now agree
#120Earlier quoted context omitted.
That's so weird. I experienced the same thing the first time I took mushrooms as a teenager. I had no idea what a trip was. There were a few notable things in the trip but one thing that stood out was the eye of providence. I can't for the life of me think why that appeared since it's not something I can really associate with anything in my life up to that point. I'm not a religious person and not very spiritual but…
that's whats fucked up about it. I am not religious at all. Yet, what I experienced was on a spiritual level with real changes. it's crazy how common the themes are. did you hear extra-terrestrials? Like I literally heard a thought broadcasted from somewhere not on earth with the message "we aren't from earth but we are gonna help you out. clean your fucking room. move your computer to living room. get your shit toge…
I'm reminded of Tool's "Rosetta Stoned".[0,1]
...
10 to 2 AM, X, Yogi DMT, and a box of Krispy Kremes
...
When a flaming stealth banana split the sky
...
Then the X-Files being
...
Did a slow-mo Matrix descent
Outta the butt end of the banana vessel
And hovered above my bug-eyes, my gaping jaw
...
He said, "You are the chosen one
The one who will deliver the message
A message of hope for those who choose to hear it
And a warning for those who do not."
...
See, they took me by the hand
And invited me right in
Then they showed me something
I don't even know where to begin
...
Can't remember what they said
...
Overwhelmed as one would be, placed in my position
Such a heavy burden now to be the one
Born to bear and bring to all the details of our ending
To write it down for all the world to see
But I forgot my pen
...
0) https://www.youtube.com/watch?v=VZXJLQntCP0