11–20 of 114 posts
From the abstract: [...] Quality pre and post treatment fMRI data were collected from 16 of 19 patients. Decreased depressive symptoms were observed in all 19 patients at 1-week post-treatment and 47% met criteria for response at 5 weeks. [...]
Before self-medicating based on this combined with a self-diagnosis, consider that LSD and psilocybin have a nasty tendency of triggering latent psychological conditions if not taken in the appropriate dosage and in a controlled environment. [ref: http://www.nationaldrugstrategy.gov.au/internet/drugstrategy... ]
Could it also be the case that people with potential mental illnesses is more likely to try drugs? Therefore being a correlational relationship instead of a causal one?
From the abstract: [...] Quality pre and post treatment fMRI data were collected from 16 of 19 patients. Decreased depressive symptoms were observed in all 19 patients at 1-week post-treatment and 47% met criteria for response at 5 weeks. [...]
N=19 is a very small sample size. I would be careful forming opinions based on this study.
Assuming that psilocybin is effective at treating depression, I find myself wondering whether actual conscious experience (that is, being high) is an essential part of its effectiveness or not. To put this another way, imagine someone takes whatever dose of psilocybin and then is rendered unconsciousness until the perceptual effects wear off. Will there be any difference in its effectiveness as a treatment for depres…
Also, you’d definitely need to be rendered unconscious, haha—I can’t imagine trying to sleep naturally on mushrooms, although when I take them I always have the most beautifully restful sleep after coming down.
Assuming that psilocybin is effective at treating depression, I find myself wondering whether actual conscious experience (that is, being high) is an essential part of its effectiveness or not. To put this another way, imagine someone takes whatever dose of psilocybin and then is rendered unconsciousness until the perceptual effects wear off. Will there be any difference in its effectiveness as a treatment for depres…
In either case, it may explain some habitual drugs users who are actually self-medicating. It could be that in a few years, they're doing the exact same thing but with a prescription to make it all morally upstanding.
[0]Correct me if I'm misunderstanding.
Assuming that psilocybin is effective at treating depression, I find myself wondering whether actual conscious experience (that is, being high) is an essential part of its effectiveness or not. To put this another way, imagine someone takes whatever dose of psilocybin and then is rendered unconsciousness until the perceptual effects wear off. Will there be any difference in its effectiveness as a treatment for depres…
Neurogenesis in general seems to be inversely proportional to experiences of depression.
Before self-medicating based on this combined with a self-diagnosis, consider that LSD and psilocybin have a nasty tendency of triggering latent psychological conditions if not taken in the appropriate dosage and in a controlled environment. [ref: http://www.nationaldrugstrategy.gov.au/internet/drugstrategy... ]
Is there proof that they have a tendency of triggering "latent" conditions, instead of generating the conditions? How can it be demonstated that conditions were latent before the use? Could it also be the case that people with potential mental illnesses is more likely to try drugs? Therefore being a correlational relationship instead of a causal one?
Assuming that psilocybin is effective at treating depression, I find myself wondering whether actual conscious experience (that is, being high) is an essential part of its effectiveness or not. To put this another way, imagine someone takes whatever dose of psilocybin and then is rendered unconsciousness until the perceptual effects wear off. Will there be any difference in its effectiveness as a treatment for depres…
I would assume so, that it’d be akin to a strong one-shot antidepressant. Psilocybin is quickly metabolised to psilocin, which binds to serotonin receptors. It might be more of a risk for a bad trip, though, unless you have good dream control. Also, you’d definitely need to be rendered unconscious, haha—I can’t imagine trying to sleep naturally on mushrooms, although when I take them I always have the most beautifull…
Assuming that psilocybin is effective at treating depression, I find myself wondering whether actual conscious experience (that is, being high) is an essential part of its effectiveness or not. To put this another way, imagine someone takes whatever dose of psilocybin and then is rendered unconsciousness until the perceptual effects wear off. Will there be any difference in its effectiveness as a treatment for depres…
Yes, it would still work because the current hypothesis is that it's the resulting increase in neurogenesis which is responsible for the amelioration of depression. Neurogenesis in general seems to be inversely proportional to experiences of depression.
Assuming that psilocybin is effective at treating depression, I find myself wondering whether actual conscious experience (that is, being high) is an essential part of its effectiveness or not. To put this another way, imagine someone takes whatever dose of psilocybin and then is rendered unconsciousness until the perceptual effects wear off. Will there be any difference in its effectiveness as a treatment for depres…
To refine your question further[0]: is this an effect of the psychological experience of tripping on mushrooms, or is this a physiological effect of the drug itself? In either case, it may explain some habitual drugs users who are actually self-medicating. It could be that in a few years, they're doing the exact same thing but with a prescription to make it all morally upstanding. [0]Correct me if I'm misunderstandin…