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Can the Bacteria in Your Gut Explain Your Mood?

nytimes.com

31–40 of 50 posts

Re: Can the Bacteria in Your Gut Explain Your Mood?

#31

It's a little concerning that Mazmanian believes that diet can help autism, when all the placebo-controlled trials show that none of the weird and wacky diets actually work.

While not conclusive, there is actually some evidence a ketogenic diet may help.

Re: Can the Bacteria in Your Gut Explain Your Mood?

#32
post #23

There is a simpler question - could one tell anxiety from hunger? (I can't) or the feeling of being hungry "reuses anxiety" in context? This explains why stressed people are overeating - they misinterpret their anxiety as feeling hungry and develop a habit of "eating it over". Bacteria stuff is just BS.

"Bacteria stuff is just BS." Why? References? "There is a simpler question - could one tell anxiety from hunger? (I can't) or the feeling of being hungry "reuses anxiety" in context? This explains why stressed people are overeating - they misinterpret their anxiety as feeling hungry and develop a habit of "eating it over". Actually it doesn't. Why are they feeling anxious? How do they misinterpret anxiety for the fee…

Because which set of bacteria one has in ones gut depends of location, season, humidity, air quality, traditional foods, water sources, other bacteria an another hundred factors.

Anxiety disorders are human universal.

Re: Can the Bacteria in Your Gut Explain Your Mood?

#33

It's a little concerning that Mazmanian believes that diet can help autism, when all the placebo-controlled trials show that none of the weird and wacky diets actually work.

While not conclusive, there is actually some evidence a ketogenic diet may help.

As far as I can tell it was uncontrolled, which doesn't really tell us anything (as there will be a large placebo effect).

Re: Can the Bacteria in Your Gut Explain Your Mood?

#34
post #6

Earlier quoted context omitted.

> Yet I haven't seen any life-changing results. Not trying to be a smartass, but "not seeing something" is not really a convincing argument if you have never looked for it before. Especially here, given that there is no obvious feedback loop to give us hints at the relation between the gut flora and our mood. (are you aware of changes in your digestive chemistry and gut flora? How would you connect that to emotional…

It's presented as a dismissive question with no answer. But with the number and amount of antibiotics prescribed, wouldn't you expect a lot of curious, seemingly miraculous changes by accident? You know when you take antibiotics. You have a clear time frame, and the event is unusual enough that it should stand out.

Well, the people in question are already in the hospital or long term care for some reason, so there's an unfamiliar environment, stresses related to why they're there, etc. Not hard to find reasons for behavior or mood changes there even without addressing the microbiome.

Re: Can the Bacteria in Your Gut Explain Your Mood?

#35

I'm curious why these articles are posted so often on HN. Do a lot of people here have mood disorders? If so, would it not be better to look at the more obvious causes -- lifestyle and stress -- rather than trying to pin the blame on some outside entity? There really isn't much if any evidence supporting this hypothesis at the moment, and even if there is an effect it appears to be relatively minor.

There seem to be a lot of bio / pharma readers here, and I appreciate their input into things like this where I might not have otherwise run into them.

In the end medicine comes down to data mining and statistics, with a lot of computer science lineage.

And for that matter, the whole startup scene exists on the wet side of the fence too.

(And also, I suspect that a lot of us here self diagnose our mental state, thus making any information like this of interest.)

Re: Can the Bacteria in Your Gut Explain Your Mood?

#36
post #30
post #19

Another thing I've been pondering occasionally is what this and other discoveries might mean if cryonic neuropreservation (head/brain only) storage & reversal is ever practical, or if full head transplants become a viable surgery. Just how much of actual personness is stored in places other than just the brain? Surely the hormonal (endocrine?) systems of the body, as well as things like the microbiome are going to pl…

In Principles of Psychology , William James speculated that any kind of non-corporeal afterlife would necessarily be non-emotional, since our emotions are felt in our bodies rather than our brains.

If we ever managed to emulate our consciousness on other hardware, wouldn't we be also able to emulate bodily sensations and emotions?

Re: Can the Bacteria in Your Gut Explain Your Mood?

#38

There is a simpler question - could one tell anxiety from hunger? (I can't) or the feeling of being hungry "reuses anxiety" in context? This explains why stressed people are overeating - they misinterpret their anxiety as feeling hungry and develop a habit of "eating it over". Bacteria stuff is just BS.

Um... When I was suffering very bad anxiety I was unable to keep food down due to the anxiety and it certainly didn't feel anything like hunger.

Re: Can the Bacteria in Your Gut Explain Your Mood?

#39
post #19

Another thing I've been pondering occasionally is what this and other discoveries might mean if cryonic neuropreservation (head/brain only) storage & reversal is ever practical, or if full head transplants become a viable surgery. Just how much of actual personness is stored in places other than just the brain? Surely the hormonal (endocrine?) systems of the body, as well as things like the microbiome are going to pl…

Antonio Damasio's Somatic Marker hypothesis goes into this and completely changed the way I observed my own mood and emotional state. His book Descartes' Error is a good read if you want to look into it.

Re: Can the Bacteria in Your Gut Explain Your Mood?

#40
post #36
post #30

Earlier quoted context omitted.

In Principles of Psychology , William James speculated that any kind of non-corporeal afterlife would necessarily be non-emotional, since our emotions are felt in our bodies rather than our brains.

If we ever managed to emulate our consciousness on other hardware, wouldn't we be also able to emulate bodily sensations and emotions?

I guess it depends if your emotional configuration is still stored somewhere, or if it was lost when cryo-preserving your head only.
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