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Diet that mimics fasting appears to slow aging

news.usc.edu

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Re: Diet that mimics fasting appears to slow aging

#41

Post by kristopolous »

Rainymood wrote: post #38

I currently intermittent fast by skipping breakfast + lunch, partially because I'm lazy, partially because it allows me to easily eat 'all my calories' in the end of the day. I really like this as it provides a 'buffer' for unexpected food, such as random cake, or random lunches with colleagues etc. Has anyone here actually ever TRIED fasting a full 24h day? I have. I HATED it. Well, the fasting itself wasn't that ba…

I believe there's some consensus that eating closer to the time you wake is more advisable then closer to the time you sleep - all other things being equal.

Re: Diet that mimics fasting appears to slow aging

#42

Post by IndianAstronaut »

stevebmark wrote: post #29

Ketosis also "mimics fastings", the main metabolic difference being nutritional ketosis is 0.5 - 3 mmol/L, while fasting is 3 - 5 mmol/L (betahydroxybuterate in the serum). The benefits of ketosis may also add longevity, possibly with similar mechanisms to fasting. It's likely intermittent fasting put the subjects of the study into mild ketosis. Bottom line: Ketosis may have benefits similar to fasting in terms of ag…

>Ketosis also "mimics fastings",

Can you please provide a source on this?

Re: Diet that mimics fasting appears to slow aging

#43

Post by spiritplumber »

heimatau wrote: post #40
Rainymood wrote: post #38

I currently intermittent fast by skipping breakfast + lunch, partially because I'm lazy, partially because it allows me to easily eat 'all my calories' in the end of the day. I really like this as it provides a 'buffer' for unexpected food, such as random cake, or random lunches with colleagues etc. Has anyone here actually ever TRIED fasting a full 24h day? I have. I HATED it. Well, the fasting itself wasn't that ba…

The first three days of 24 hour day fasts are (:edited:) mostly painful. Headaches, migraines, agitation, etc. They are not fun nor for the faint of heart. I'd suggest a five day, if you body can allow it. Days four through ten can be the most rewarding. This is all based on personal experience/opinion.

The longest I've gone without eating was three days... it's liveable, but I can't get anything done!

Can't code, can't solder, can't do circuit design....

Re: Diet that mimics fasting appears to slow aging

#44

Post by rlucas »

Rainymood wrote: post #38

I currently intermittent fast by skipping breakfast + lunch, partially because I'm lazy, partially because it allows me to easily eat 'all my calories' in the end of the day. I really like this as it provides a 'buffer' for unexpected food, such as random cake, or random lunches with colleagues etc. Has anyone here actually ever TRIED fasting a full 24h day? I have. I HATED it. Well, the fasting itself wasn't that ba…

You've got to get past about 36 hours before your body / brain stop acting so "berserk." After that, you stop being hungry and you can look at food with relative equanimity.

Re: Diet that mimics fasting appears to slow aging

#46

Post by reasonattlm »

tosseraccount wrote: post #32
reasonattlm wrote: post #27

There is much more background info on Longo and his work on intermittent fasting if you go digging. More interesting than this particular piece, which is very short on context and science relating to the study of intermittent fasting, calorie restriction as adjuvant cancer therapy, immune regeneration via fasting, etc. http://gero.usc.edu/faculty/longo/ http://www.eurekalert.org/pub_releases/2014-06/uosc-fts06021...…

Can you tl;dr , please. Does adjuvant therapy in the form of fasting affect survival in clinical trials in cancer patients? Is this proven and accepted?

Sure. It's a thing. See this:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815756/

"Proven" is of course a continuum rather than a binary state. There's plenty of evidence to suggest that calorie restriction and fasting are beneficial across the board, and in cancer, and specifically as adjuvants. Getting that past the FDA as an official approved treatment is still ongoing, I believe. Most likely because "eating less" is not attached to "we can make a huge amount of money charging for this" so who is going to pay for all the studies and data that the FDA wants? One of Longo's innovations is to have found a way to make that happen within the system, I think.

More:

https://www.google.com/webhp?#q=cancer%20%22dietary%20restri...

Re: Diet that mimics fasting appears to slow aging

#47

Post by [deleted] »

Rainymood wrote: post #38

I currently intermittent fast by skipping breakfast + lunch, partially because I'm lazy, partially because it allows me to easily eat 'all my calories' in the end of the day. I really like this as it provides a 'buffer' for unexpected food, such as random cake, or random lunches with colleagues etc. Has anyone here actually ever TRIED fasting a full 24h day? I have. I HATED it. Well, the fasting itself wasn't that ba…

[deleted]

Re: Diet that mimics fasting appears to slow aging

#48

Post by vlasev »

heimatau wrote: post #40
Rainymood wrote: post #38

I currently intermittent fast by skipping breakfast + lunch, partially because I'm lazy, partially because it allows me to easily eat 'all my calories' in the end of the day. I really like this as it provides a 'buffer' for unexpected food, such as random cake, or random lunches with colleagues etc. Has anyone here actually ever TRIED fasting a full 24h day? I have. I HATED it. Well, the fasting itself wasn't that ba…

The first three days of 24 hour day fasts are (:edited:) mostly painful. Headaches, migraines, agitation, etc. They are not fun nor for the faint of heart. I'd suggest a five day, if you body can allow it. Days four through ten can be the most rewarding. This is all based on personal experience/opinion.

One thing to keep in mind is that you need to drink lots of water during that time because you'll be using your fat deposits and you need water to process the fat.

Re: Diet that mimics fasting appears to slow aging

#49

Post by MCRed »

biomcgary wrote: post #37
reasonattlm wrote: post #27

There is much more background info on Longo and his work on intermittent fasting if you go digging. More interesting than this particular piece, which is very short on context and science relating to the study of intermittent fasting, calorie restriction as adjuvant cancer therapy, immune regeneration via fasting, etc. http://gero.usc.edu/faculty/longo/ http://www.eurekalert.org/pub_releases/2014-06/uosc-fts06021...…

I also recommend looking elsewhere since the OP is an example of terrible science. Due to the proprietary nature of the diet this study is impossible for an unbiased researcher to replicate.

Why is the diet proprietary? Is he publishing without revealing sufficient detail for it to be replicated? Or is this some secret business oriented research that's going on?

I think it wouldn't really be science relevant without revealing the diet so we can look at the nutrients and compare that to the research.

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