Strange nobody mentioned Nassim Taleb and his work on that matter: The Precautionary Principle - www.fooledbyrandomness.com/pp2.pdf Quoting the first paragraph of the paper: The precautionary principle (PP) states that if an action or policy has a suspected risk of causing severe harm to the public domain (affecting general health or the environment globally), the action should not be taken in the absence of scientif…
The act of publishing a book or an article (edit: or a cartoon), has occasionally led to far-reaching, sometimes violent, unforeseen and unpredictable systemic consequences, sometimes bringing down governments. Yet Taleb has published several, apparently with no concern whatsoever about his own precautionary principle.
PP is used when a system, in this case the humanity, is at risk of total failure, i.e. ruin.