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Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

scientificamerican.com

21–30 of 159 posts

Re: Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

#21
Very early in the research, if I am to just go off the article. First, the article really only addresses saccharin. Second, the healthy volunteer study appears to use max daily acceptable intake, which sounds reasonable at first. The amount, however, is the equivalent of 250 packets of sweet and low:

http://www.fda.gov/Food/IngredientsPackagingLabeling/FoodAdd...

Re: Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

#22
It's entirely possible that this is just sloppy science journalism, but the distinction the SA article mentions sounds a bit ridiculous.

"In the Israeli experiment, 10-week-old mice were fed a daily dose of aspartame, sucralose or saccharin. Another cluster of mice were given water laced with one of two natural sugars, glucose or sucrose.

After 11 weeks, the mice receiving sugar were doing fine, whereas the mice fed artificial sweeteners had abnormally high blood sugar (glucose) levels, an indication that their tissues were having difficulty absorbing glucose from the blood. "

So you feed group B sugar, and group A things that are not sugar, and then you put both groups through a glucose challenge, administering a calibrated amount of sugar, and group A's blood sugar spikes higher than group B's, which is not acclimated to metabolizing sugar. This is not surprising.

I suppose I'd need to read the journal article later when I have time, to be sure. There are a lot of things that look like interesting correlations in tests like this that actually aren't, when you control for all of the variables, and consider the short-term and long-term adaptations the body makes.

Re: Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

#23
I think one of the most important things to keep in mind when reading articles like this is the old mantra that "correlation does not equal causation". I'm always a bit skeptical when studies show partially successful statistics.

I've done a lot of research on the subject at hand, and I still believe that consuming real sugar is orders of magnitudes worse than using sweeteners.

Re: Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

#24
post #23

I think one of the most important things to keep in mind when reading articles like this is the old mantra that "correlation does not equal causation". I'm always a bit skeptical when studies show partially successful statistics. I've done a lot of research on the subject at hand, and I still believe that consuming real sugar is orders of magnitudes worse than using sweeteners.

> I've done a lot of research on the subject at hand, and I still believe that consuming real sugar is orders of magnitudes worse than using sweeteners.

For the gut, or in general? If for the gut, please expand.

Re: Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

#25
post #23

I think one of the most important things to keep in mind when reading articles like this is the old mantra that "correlation does not equal causation". I'm always a bit skeptical when studies show partially successful statistics. I've done a lot of research on the subject at hand, and I still believe that consuming real sugar is orders of magnitudes worse than using sweeteners.

[deleted]

Re: Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

#26
post #22

It's entirely possible that this is just sloppy science journalism, but the distinction the SA article mentions sounds a bit ridiculous. "In the Israeli experiment, 10-week-old mice were fed a daily dose of aspartame, sucralose or saccharin. Another cluster of mice were given water laced with one of two natural sugars, glucose or sucrose. After 11 weeks, the mice receiving sugar were doing fine, whereas the mice fed…

It looks like a good start to doing some more serious research, especially the human study. But as I mentioned in a comment, the healthy volunteer study appears to use max daily acceptable intake, which sounds reasonable at first. The amount, however, is the equivalent of 250 packets of sweet and low. That is the sloppy part of the article to me.

Re: Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

#27
post #9

Does anyone have any thoughts how Xylitol or Erythritol might fare under a study like this? They're currently my go to sweeteners. I'm not sure why they're not more popular.

Both of those are sugar alcohols, and as such have laxative effects, among other things.

But no idea how they'd fare under this sort of study.

Re: Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

#28

Earlier quoted context omitted.

I'm not sure that stevia is an "artificial" sweetener.

It's natural, but there are doubts about its safety. In many countries it is still banned. And in countries like the USA it has only been available for a short period of time (after lots of lobbying).

There aren't doubts about its safety, and reading about it a lot, I am not convinced there ever were that were based on data - seems they all had to do with scare tactics.

In the USA it was available until 1991 with not a single medical case against it - and again since 1994 (simultaneously considered "safe" on its own but "not enough data to classify as safe" as an additive).

Not to mention, it has more than a thousand year of use. See wikipedia[0] about history and also the part of "controversy".

Unlike the egg/cholesterol and salt intake recommendations, which appear to be grounded in scientific incompetence, any concerns about stevia seem to be strategically managed by a competitor.

[0] http://en.wikipedia.org/wiki/Stevia#History

Re: Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

#29
post #23

I think one of the most important things to keep in mind when reading articles like this is the old mantra that "correlation does not equal causation". I'm always a bit skeptical when studies show partially successful statistics. I've done a lot of research on the subject at hand, and I still believe that consuming real sugar is orders of magnitudes worse than using sweeteners.

Sample size of one here, but no amount of additional exercise or any other dietary change has ever helped my weight or overall energy level as switching from Coke to Diet Coke many years ago. The effect was nearly instant, dramatic, and permanent. Probably like many things, there are just too many variables to say A is good and B is bad.

Re: Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

#30
post #9

Does anyone have any thoughts how Xylitol or Erythritol might fare under a study like this? They're currently my go to sweeteners. I'm not sure why they're not more popular.

Xylitol is not more popular because a tiny dose will kill a dog. I use it as well, but am very careful with it. I treat it essentially like poison.
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