What are people's favorite guides for setting up Ubuntu? http://www.funnestra.org/ubuntu is really good but they don't have a 9.10 update yet.
In all seriousness, "guides" for setting up Ubuntu are most likely unnecessary or superfluous; they'll just go into some random area of "customization" that 95% of users probably don't need or care about.
If you already have an older version of Ubuntu, just run the command I mentioned, or go to System->Update Manager to handle the upgrade, and get on with your day. If you don't have Ubuntu, just boot the live disc and install it, and go from there.