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Dementia 'linked' to common over-the-counter drugs

bbc.co.uk

21–30 of 62 posts

Re: Dementia 'linked' to common over-the-counter drugs

#21
post #17

Earlier quoted context omitted.

I'm mostly referring to symptoms and lesser illnesses such as colds, headaches, sores and such

An open wound was almost certainly a recipe for gangrene prior to antiseptics and antibiotics.

I think this straying from my main point. All I was trying to say is when possible stick to natural stuff in all other circumstances I'm all for modern medicines.

Re: Dementia 'linked' to common over-the-counter drugs

#22

Earlier quoted context omitted.

That Placebo Effect is so strong I don't even bother to debunk natural remedies. Plus, I might be throwing the baby out with the bath water, but right now I'm very skeptical of a lot of pharmacuticals studies. They just lied to us so many times when it comes to the efficacy of their newest drug.

I get your skepticism, but does it not help that pharmaceutical studies are closely reviewed by the FDA before a drug can be marketed? Getting a new drug approved is far from easy.

It's also not that hard---perform your own research, under conditions you specify, using analysis methods you dictate, with the ability to retry over and over and over until a favorable result arises by chance, THEN the FDA scrutinizes it.

Re: Dementia 'linked' to common over-the-counter drugs

#23
post #17

Earlier quoted context omitted.

I'm mostly referring to symptoms and lesser illnesses such as colds, headaches, sores and such

An open wound was almost certainly a recipe for gangrene prior to antiseptics and antibiotics.

In this study[0], honey compares favorably to silver sulfadiazine dressing for healing burn wounds.

[0] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845359/

Re: Dementia 'linked' to common over-the-counter drugs

#24
post #14

Somewhat unsurprising to me. I once accidentally overdosed on an anticholinergic drug, and it was the most unpleasant experience of my life. It was a combination of psychosis and hallucinations coupled with what I imagine dementia to be like. Hideous. Of course, expect the two to be linked in the long term is ridiculous on my behalf, but if it can have that effect in the short term...

For what it's worth, diphenhydramine (mentioned in the article) is Benadryl, and it's widely known that it causes hallucinations in high doses:

https://www.erowid.org/pharms/diphenhydramine/diphenhydramin...

Re: Dementia 'linked' to common over-the-counter drugs

#25
post #2

I stopped taking over-the-counter drugs years ago unless its vitally necessary. Common colds, allergies etc are not too difficult to bear in most circumstances and with the all the side-effects of pharma drugs I prefer to go with alternative medicines ex. local honey, lemons, etc.

Honest question: what convinces you that over-the-counter drugs have a negative effect rather than a neutral or even positive effect?

Re: Dementia 'linked' to common over-the-counter drugs

#27
post #16

I wonder if choline supplementation would counteract this effect. In fact, I wonder if choline supplementation might help stave off dementia in general. As much as 90% of the population may be deficient in choline.[0] [0] http://en.wikipedia.org/wiki/Choline#Groups_at_risk_for_chol...

(Wild speculation ahead)

I think it has to -- almost all of the nootropics that people use (-iracetams) are recommended to be taken with choline supplements, as people tend to get headaches without them. These nootropics were looked at as Alzheimer-preventing or -delaying drugs, and they cause an uptick in choline use that necessitates the supplements. I feel that indicates choline is used in keeping the mind strong against Alzheimers.

Re: Dementia 'linked' to common over-the-counter drugs

#28
Is it that surprising that inhibiting choline would be a bad idea? Choline's positive effects on memory and the brain are very well known and increases in acetylcholine are one of the main methods of actions of nootropics in the racetam class.

Profound effects of combining choline and piracetam on memory enhancement and cholinergic function in aged rats. http://www.ncbi.nlm.nih.gov/pubmed/7301036

Effects of citicholine and of the combination citicholine + piracetam on the memory (experiments on mice). http://www.ncbi.nlm.nih.gov/pubmed/2392950

Comparative studies on the effects of the nootropic drugs adafenoxate, meclofenoxate and piracetam, and of citicholine on scopolamine-impaired memory, exploratory behavior and physical capabilities (experiments on rats and mice). http://www.ncbi.nlm.nih.gov/pubmed/3136617

Re: Dementia 'linked' to common over-the-counter drugs

#29
post #18
post #2

I stopped taking over-the-counter drugs years ago unless its vitally necessary. Common colds, allergies etc are not too difficult to bear in most circumstances and with the all the side-effects of pharma drugs I prefer to go with alternative medicines ex. local honey, lemons, etc.

I feel obligated to say that "alternative medicine" means treatment attempts that are not based on science or evidence.

They are based on evidence, but that evidence has not been scientifically evaluated.

Re: Dementia 'linked' to common over-the-counter drugs

#30

Earlier quoted context omitted.

> I prefer to go with alternative medicines ex. local honey, lemons, etc. These alternatives clearly have the advantage of being side-effect free for most people, but I have always been very skeptical about their effectiveness. Are there actually any reliable studies on the efficacy of local honey in treating allergies? And I thought that the role of vitamin C in warding off colds had been pretty well debunked. (I as…

One thing I've found is that honey is an amazing sore-throat cure.

For coughs, check out olive leaf extract. I very rarely recommend things, but it's amazing how suddenly and completely it makes you stop coughing!
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