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Telomere extension turns back aging clock in cultured human cells, study finds

med.stanford.edu

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Re: Telomere extension turns back aging clock in cultured human cells, study finds

#51
post #14

Earlier quoted context omitted.

Keep in mind that evolution works primarily at a subspecies level, so any mutations which benefited that lineage at the expense of the species as a whole would tend to be favored.

Actually, evolution is almost entirely dominated by selection at the individual level, with a modicum of kin selection thrown in. The notion that selection acts at other levels is highly speculative (I wrote a novel based on the idea, but it's the purest kind of speculative fiction: http://www.amazon.com/Darwins-Theorem-TJ-Radcliffe-ebook/dp/... )

Sounds like you're agreeing with me? By "lineage" I'm talking primarily about the lineage of a gene, or in many cases the so-called inclusive fitness of an individual.

Re: Telomere extension turns back aging clock in cultured human cells, study finds

#52

Earlier quoted context omitted.

I don't want a backup; I want RAID. The existence of a copy of a person does not preserve the continuity of the original.

> The existence of a copy of a person does not preserve the continuity of the original. Amazing how many people forget this simple fact.

Yes. In a skewed way, in a lot of sci-fi show, the characters commited suicide on a regular basis.

Re: Telomere extension turns back aging clock in cultured human cells, study finds

#53

Earlier quoted context omitted.

You're misreading the statistics a bit. The biggest gains in life expectancy have been at birth. There have been old people for a lot longer than the last 150 years. Even Aristotle knew about menopause. And Plato lived to be 80.

You have to remember a significant time in human evolutionary scale is probably something like 10k-100k years. Looking at wiki page for life expectacy at the Paleolithic [1] (even at 15 years) shows it lines right up with woman menopause. [1] http://en.wikipedia.org/wiki/Life_expectancy

Life expectancy is a mean value, and it's skewed by people dying young. So the life expectancy at the Paleolithic doesn't mean that people didn't survive past menopause: it means that a lot of people died young.
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