Can someone explain to me what is exactly meant by starvation in the article? Does it means that you don't go without any food for a number a days? Restrict your calorie in take to only 600 throughout the day? Only eat a single meal at night while fasting throughout the day? There really any specifics that I can see.
Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
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Re: Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
#22Note that this paper is heavy on theory, not so much on the evidence. The only "proof" of this conjecture is right at the end where they mention 10 people tried starvation before chemo and reported feeling less side-effects afterwards. I'm actually trying out an intermittent fasting diet right now for weight loss. I'm just always skeptical of new fad diets when they start claiming all sorts of health benefits beyond…
I agree. This is clearly not a double blind experiment [1]. And self reporting studies are more prone to produce false results, because the people are optimistic and want to recover and want to feel better. Also people want to be kind and make the doctors happy, so they unconsciously ignore some of the bad side effects.
And also people confuse normal variations with treatment consequences, so perhaps the persons in the treatment group classify that as an improvement and the persons in the control group classify that as normal. [2]
In this case, perhaps the comparison is worse because fasting has some side effects and you can get answers like: "I fell a little dizzy, but not as dizzy as the previous week while I was fasting." Should you classify that as an improvement?
[1] Is it possible to do a double blind experiment for this?
[2] Do they have control group?
Re: Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
#23Earlier quoted context omitted.
>I'm actually trying out an intermittent fasting diet right now for weight loss. I'm just always skeptical of new fad diets when they start claiming all sorts of health benefits beyond weight loss. Weightloss. To me, still means in I fast (skip breakfast/lunch and drink coffee) and start eating when I get back home out of work. I love it because I build up a 'caloric buffer', for when something unexpected happens (ra…
The "in People get fat because they eat the wrong food, of which the effect of making them hungry and eat even more is only one of the many detrimental effects of unsuitable food for us or other animals. I don't write this to change your mind, but hope that if someone else reads this, at least this might give them some encouragement, so that they might persist through to read about the issue themselves. It really is…
Reasonable post up until the point where you claimed eating right cures cancer
Re: Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
#24Note that this paper is heavy on theory, not so much on the evidence. The only "proof" of this conjecture is right at the end where they mention 10 people tried starvation before chemo and reported feeling less side-effects afterwards. I'm actually trying out an intermittent fasting diet right now for weight loss. I'm just always skeptical of new fad diets when they start claiming all sorts of health benefits beyond…
Proof is the wrong term here, I understand you put it in quotations but the correct term would be 'evidence'.
In studies like this, there is no proof, there is only evidence for different arguments.
In terms of your intermittent fasting diet. Meal timing won't really affect weight loss, what will affect weight loss is your overall energy balance (deficit or surplus), and to a lesser extent macronutrient intake (possible slight fat burn from thermic effect of feeding with higher protein).
Re: Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
#25Earlier quoted context omitted.
>I'm actually trying out an intermittent fasting diet right now for weight loss. I'm just always skeptical of new fad diets when they start claiming all sorts of health benefits beyond weight loss. Weightloss. To me, still means in I fast (skip breakfast/lunch and drink coffee) and start eating when I get back home out of work. I love it because I build up a 'caloric buffer', for when something unexpected happens (ra…
The "in People get fat because they eat the wrong food, of which the effect of making them hungry and eat even more is only one of the many detrimental effects of unsuitable food for us or other animals. I don't write this to change your mind, but hope that if someone else reads this, at least this might give them some encouragement, so that they might persist through to read about the issue themselves. It really is…
Almost everything you say in this post is completely wrong.
The body is not immune to the law of conservation of energy. If you think you can eat a caloric surplus of any food type and lose weight then you've resigned yourself to not think rationally.
Re: Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
#26Note that this paper is heavy on theory, not so much on the evidence. The only "proof" of this conjecture is right at the end where they mention 10 people tried starvation before chemo and reported feeling less side-effects afterwards. I'm actually trying out an intermittent fasting diet right now for weight loss. I'm just always skeptical of new fad diets when they start claiming all sorts of health benefits beyond…
I'm just always skeptical of new fad diets when they start claiming all sorts of health benefits beyond weight loss
There is a guy who did a nice work summarising the scientific findings.
http://www.lift-heavy.com/intermittent-fasting/
Many studies are on animal subjects, but there are human studies too which show more than just weight loss
Calorie restriction in humans is associated with weight loss, reduced inflammation and improved markers for cardiovascular and metabolic health in obese (9,10) as well as non-obese (11,12) subjects
In another study, fasting healthy men and women were compared to a matched non-fasting group with regard to inflammation markers and blood lipid status (61). No differences were observed in body weight, total cholesterol, triglycerides or LDL levels. There was however an increase in HDL levels and decreased inflammation – proposing a beneficial effect in the fasted subjects.
In obese subjects, a modified 8-10 week alternate-day fasting regimen resulted in weight loss, reduced blood pressure and heart rate, and improved markers for cardiovascular health, such as decreased total cholesterol, decreased LDL and triglycerides, increased HDL concentrations and decreased oxidative stress and systemic inflammation, suggesting that alternate-day fasting might be a novel strategy for decreasing body weight and improving cardiovascular health in the obese population (64,68).
eight healthy men were maintained on a 20h modified alternate-day fast for two weeks. Despite unaltered body weight and habitual physical activity, insulin dependent glucose uptake increased, and increased adiponectin levels were observed (65).
In another trial, the insulin sensitizing effect of true alternate-day fasting was observed through reduced insulin response to a standardized meal in men, but not women – suggesting a potential sex difference in the effect of alternate-day fasting on glucose metabolism (66).
I'm also doing intermittent fasting - a 36 hour fast each week - and plan to do longer fasts maybe every 3-4 months - for health reasons.
Re: Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
#27Earlier quoted context omitted.
The "in People get fat because they eat the wrong food, of which the effect of making them hungry and eat even more is only one of the many detrimental effects of unsuitable food for us or other animals. I don't write this to change your mind, but hope that if someone else reads this, at least this might give them some encouragement, so that they might persist through to read about the issue themselves. It really is…
Reasonable post up until the point where you claimed eating right cures cancer
There is nothing reasonable about it, it's completely wrong on every level.
Re: Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
#28Site seems a bit slow, so here's the abstract: Abstract Cancer patients undergoing chemotherapy treatment are advised to increase food intake to overcome the therapy-induced side effects, and weight loss. Dietary restriction is known to slow down the aging process and hence reduce age-related diseases such as cancer. Fasting or short-term starvation is more effective than dietary restriction to prevent cancer growth…
> Dietary restriction is known to slow down the aging process and hence reduce age-related diseases such as cancer
Isn't this, uh, wrong? My understanding was that calorie restriction was very promising in some animals, but that the studies were never positive for humans or large primates.
Re: Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
#29Note that this paper is heavy on theory, not so much on the evidence. The only "proof" of this conjecture is right at the end where they mention 10 people tried starvation before chemo and reported feeling less side-effects afterwards. I'm actually trying out an intermittent fasting diet right now for weight loss. I'm just always skeptical of new fad diets when they start claiming all sorts of health benefits beyond…
I'm just always skeptical of new fad diets when they start claiming all sorts of health benefits beyond weight loss There is a guy who did a nice work summarising the scientific findings. http://www.lift-heavy.com/intermittent-fasting/ Many studies are on animal subjects, but there are human studies too which show more than just weight loss Calorie restriction in humans is associated with weight loss, reduced inflamm…
In many studies they compare a control group eating a maintenance caloric intake with a fasting group that is in a caloric deficit. The results of positive health benefits of fasting usually have to do with the fact that the subjects are actually in a caloric deficit more than the studies choice of meal timing.
I'd have to dig in to those specific studies to show that, but don't read an abstract and think that it in any way tells the whole story.
Re: Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
#30Earlier quoted context omitted.
Reasonable post up until the point where you claimed eating right cures cancer
There is nothing reasonable about it, it's completely wrong on every level.
What's so unreasonable about saying that different foods can satiate you differently?
All calories are not created equally.