Sorry to be off-topic, but I was drawn to the story because of the McMaster reference and I bet some other Hamiltonians probably will be to. Would love to connect with any HN folks in Hamilton!
McMaster researchers may have found a way to restore metabolism to youth levels
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Re: McMaster researchers may have found a way to restore metabolism to youth levels
#42Type 2 diabetics improve insulin resistance: http://www.ncbi.nlm.nih.gov/pubmed/22673594
Or, you know, just put diabetes into remission and stop medication: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325029/
Pro tip: You may not need drugs to treat diabetic cases. Diabetics, barring genetic mutations, may just be carbohydrate intolerant.
Or just take some brand new drug that fucks with your body's chemical status and disregard how your body responds to food.
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#43That's patently not true. It's been known that brown fat exists in small amounts in adults for quite a long time.
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#44Type 1 (!) diabetic goes off insulin, "indicating restored insulin production"(!): http://www.ijcasereportsandimages.com/archive/provisional_ar... Type 2 diabetics improve insulin resistance: http://www.ncbi.nlm.nih.gov/pubmed/22673594 Or, you know, just put diabetes into remission and stop medication: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325029/ Pro tip: You may not need drugs to treat diabetic cases. Diabet…
The researcher appears to have a rather huge monetary investment into the paleo-style diet/care, seeing as you can order clinical care for a large sum of money from his personal site (http://paleomedicina.com/ and http://paleomedicina.com/hu/rendelesek-es-klinikai-ellatas). You'll see he has services that range up to 10,000 euros/month in Hungary, which I imagine is quite a princely sum....
Forgive me if I am making a mistake as I was using google translate, but I would definitely take that article with a grain of salt....
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#45Earlier quoted context omitted.
Fixing metabolic slowdown isn't going to end obesity or reduce the need for exercise, but it will level the playing field. It's still going to require effort, for many people, to maintain a healthy weight and exercise enough. But it's hard enough to do that as it is; if you can turn off a defect that causes the body to pile on unneeded pounds of fat (that interfere with health, mood, and the ability to exercise) with…
How is metabolic slowdown a defect? I don't see middle-aged people dropping dead around me, so clearly all that has happened is that their bodies are now more efficient. Great news! And piling on fat making it harder to exercise? Sure, on the face of it that's true, but usually the one happens because theres a dire lack of the other.
It's not low BMR alone that's the problem and, of course, if you have a high BMR but cravings/appetite issues or lethargy, you're still likely to gain weight.
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#46Type 1 (!) diabetic goes off insulin, "indicating restored insulin production"(!): http://www.ijcasereportsandimages.com/archive/provisional_ar... Type 2 diabetics improve insulin resistance: http://www.ncbi.nlm.nih.gov/pubmed/22673594 Or, you know, just put diabetes into remission and stop medication: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325029/ Pro tip: You may not need drugs to treat diabetic cases. Diabet…
The type 1 diabetic in your first linked article was very recently diagnosed before the start of the experiment and a sample size of one on a brand new diagnosis doesn't seem highly significant to me. The article had some fishy elements to it that made me want to research the authors more... The researcher appears to have a rather huge monetary investment into the paleo-style diet/care, seeing as you can order clinic…
You can also just look into the decades of research done on carbohydrates and diabetes http://www.sciencedirect.com/science/article/pii/S0899900714...
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#47This article and the researchers grossly overstate potential benefits of this research. While adults have "brown fat" there isn't a lot, certainly not enough to make up for the level of overconsumption by obese people.
It isn't appropriate to jump to conclusions about how this would work in humans based on rat experiments since rats have a much larger amount of brown fat than humans.
TL;DR: Interesting research with irresponsible and most likely incorrect assumptions about how it applies to humans.
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#48Earlier quoted context omitted.
The type 1 diabetic in your first linked article was very recently diagnosed before the start of the experiment and a sample size of one on a brand new diagnosis doesn't seem highly significant to me. The article had some fishy elements to it that made me want to research the authors more... The researcher appears to have a rather huge monetary investment into the paleo-style diet/care, seeing as you can order clinic…
Are you saying you don't believe he went off insulin, and that his data was fabricated? You can also just look into the decades of research done on carbohydrates and diabetes http://www.sciencedirect.com/science/article/pii/S0899900714...
(This comment is just about "The type 1 diabetic in your first linked article was very recently diagnosed before the start of the experiment and a sample size of one on a brand new diagnosis doesn't seem highly significant to me." I either didnt't read the rest of the comment or it got edited, with the further background research.)
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#49I don't really understand the comments here, and especially on the article itself, deriding this research because "people should just get off their butts and exercise" or similar. I'm sure the researchers wouldn't dispute the benefits of exercise. But if there really is a safe, effective way to improve the metabolism and make it easier to keep off fat, why exactly is that a bad thing? (Naturally the research is far t…
There are few topics that create as much controversial conversation. The well known ones are religion and politics, the third is 'diet/exercise.' Always a lot of energy.
1. Our ways > your ways.
2. Nuh uh.
3. (Optional) Wanna fight about it?
Iterate!
(HN version of #2: "Hyperlinks to statistically rigorous peer reviewed studies or GTFO")
Re: McMaster researchers may have found a way to restore metabolism to youth levels
#50Earlier quoted context omitted.
Taking that hypothesis, do you suppose that the lengthening of the life expectancy of developed countries has had a negative impact on said countries? Or do you think about life prolongation is a good thing up to a point?
It's a good thing up to a point, but we're seeing the negative sides of it too. Namely, we as a society expend a lot of resources on prolonging our lives (in the form of health care costs). We're probably about as far as we can go on life expectancy using cheap/preventative methods like antibiotics and diet/lifestyle changes. So any additional growth in life expectancy will probably be exponentially more expensive (a…
I don't think one caused the other.